MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984]	1136	HSPE1	Measured	Divided	5790.65	6303.92	1.08864
	1140			Subtracted			513.27
	1902		Rooted		63.4353	65.2789	1.8436
	1907			Divided			1.02906
	1933		Ranked	Subtracted	211.633	213.703	2.07
	1963			Divided			1.00978
10-formyltetrahydrofolate dehydrogenase (ec 1.5.1.6) (10-fthfdh). [swissprot;acc:o75891]	2922	ALDH1L1	Measured		0.00001	0.00001	1
				Subtracted	0	0	0
			Ranked	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
			Squared	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
			Rooted	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
14-3-3 protein beta/alpha (protein kinase c inhibitor protein-1) (kcip-1) (protein 1054). [swissprot;acc:p31946]	792	YWHAB	Squared		28551.5	32561.8	4010.3
	1143			Divided			1.14046
	1411		Measured		5812.02	6262.07	1.07743
	1422			Subtracted			450.05
	1943		Rooted	Divided	61.3337	63.0838	1.02853
	1987			Subtracted			1.7501
	2421		Ranked		220.681	221.425	0.744
	2439			Divided			1.00337
14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655]	3088	YWHAE	Measured		0.00001	0.00001	1
				Subtracted	0	0	0
			Ranked	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
			Squared	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
			Rooted	Divided	0.00001	0.00001	1
				Subtracted	0	0	0
14-3-3 protein zeta/delta (protein kinase c inhibitor protein-1) (kcip-1) (factor activating exoenzyme s) (fas). [swissprot;acc:p29312]	778	YWHAZ	Squared		28600.9	32641.7	4040.8
	1135			Divided			1.14128
	1415		Measured		5815.33	6265.44	1.0774
	1418			Subtracted			450.11
	1961		Rooted	Divided	61.3419	63.0743	1.02824
	2002			Subtracted			1.7324
	2391		Ranked		220.683	221.51	0.827
	2396			Divided			1.00375
14.5 kda translational inhibitor protein (p14.5) (uk114 antigen homolog). [swissprot;acc:p52758]	786	HRSP12	Squared	Subtracted	25739.7	29768.2	4028.5
	921			Divided			1.15651
	1404		Measured	Subtracted	6336.22	6788.96	452.74
	1600			Divided			1.07145
	1933		Rooted	Subtracted	66.966	68.7832	1.8172
	2036			Divided			1.02714
	2366		Ranked		203.353	202.529	1.00407
	2393			Subtracted			0.824
15 kda selenoprotein precursor. [swissprot;acc:o60613]	590	no value	Squared		29772.1	34456.5	4684.4
	865		Measured		6344.41	6933.36	588.95
	914		Squared	Divided	29772.1	34456.5	1.15734
	1043		Measured		6344.41	6933.36	1.09283

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.