MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Gene Enrichment

The table below show, solely based on the number of genes affected in a specific categroy, which classes are enriched (up) or depleted (down). Thje p-value is calculated according to 'GOToolBox: functional analysis of gene datasets based on Gene Ontology - David Martin, Christine Brun, Elisabeth Remy, Pierre Mouren, Denis Thieffry and Bernard Jacq'. We used the mouse-goa annotation from 2005 to perform this analysis. Resetting the view coordinate localhost/Mk5/GEGOMouse05/

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p	Ratio	description	Accession	neuronal

Results: HTML CSV LaTeX

Showing element 1 to 50 of 239 in total

p	Ratio	description	neuronal
0	down	nucleus	no value
	up	cytoplasmic vesicle
		dephosphorylation
		homoiothermy
		ice binding
		membrane
		protein binding
		response to freezing
		response to stimulus
		small conjugating protein ligase activity
1.04188e-19	down	catalytic activity
4.41122e-18		extracellular space
5.32447e-12	up	cytoplasm
3.69233e-11	down	receptor activity
5.351e-09	up	cell junction
1.31078e-08		RNA splicing
7.50539e-08		Golgi apparatus
2.27862e-07	down	olfactory receptor activity	1
8.19712e-07		structural constituent of ribosome	no value
9.09018e-07		integral to membrane
1.17775e-06	up	regulation of progression through cell cycle
1.44966e-06	down	nucleic acid binding
6.18855e-06		translation
8.24263e-06	up	structural constituent of cell wall
1.71601e-05		protein kinase activity
1.89325e-05		phosphoric monoester hydrolase activity
2.44289e-05		cell-cell signaling
2.51477e-05	down	ribosome
3.21095e-05	up	membrane fraction
3.25409e-05	down	G-protein coupled receptor protein signaling pathway
5.20983e-05	up	integral to plasma membrane
6.03978e-05	down	protein ubiquitination
7.91323e-05	up	protein C-terminus binding
0.000237102		nucleocytoplasmic transport
0.00038871	down	external side of plasma membrane
0.000408197	up	flagellin-based flagellum
		mRNA transport
0.000541705	down	ubiquitin ligase complex
0.000654237		zinc ion binding
0.000762333	up	protein dimerization activity
0.000793622		GTPase activity
0.000857538		glycerol metabolic process
0.000975592		transcription
0.00115531		neuropeptide hormone activity	1
0.00123417	down	ATP binding	no value
0.00127674		antigen binding
0.00141209	up	extracellular region
0.00235127		anion exchanger activity
		arylamine N-acetyltransferase activity
		ciliary or flagellar motility

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- Accession is the GO accession key.
- Part of neuralk circuitery.