MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1958 to 2007 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	Interaction Map	red	green	network_comparison
bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]	273	BEST1	Subtracted	Low confidence	37.318	28.4944	8.8236
bet3 homolog. [swissprot;acc:o43617]	327	TRAPPC3	Divided		197.221	189.574	1.04034
	348		Subtracted				7.647
	567		Divided	High confidence	129.219	121.261	1.06563
	910		Subtracted				7.958
bet5 homolog (multiple myeloma protein 2) (mum-2). [swissprot;acc:q9y5r8]	1058	TRAPPC1	Divided	Low confidence	198.804	194.142	1.02401
	1093		Subtracted				4.662
beta adducin (erythrocyte adducin beta subunit). [swissprot;acc:p35612]	1448	ADD2			205.847	201.577	4.27
	1549		Divided				1.02118
	1897		Subtracted	High confidence	224.343	222.151	2.192
	1945		Divided				1.00987
beta enolase (ec 4.2.1.11) (2-phospho-d-glycerate hydro-lyase) (skeletal muscle enolase) (mse) (enolase 3). [swissprot;acc:p13929]	2361	ENO3			207.186	208.046	1.00415
	2364		Subtracted				0.86
	4628		Divided	Low confidence	201.961	200.622	1.00667
	4633		Subtracted				1.339
beta tubulin 1, class vi. [refseq;acc:nm_030773]	2985	TUBB1	Divided		200.1	196.798	1.01678
	3000		Subtracted				3.302
beta-1,3-galactosyltransferase 5 (ec 2.4.1.-) (beta-1,3-galtase 5) (beta3gal-t5) (b3gal-t5) (udp-galactose:beta-n-acetylglucosamine beta- 1,3-galactosyltransferase 5) (udp-gal:beta-glcnac beta-1,3- galactosyltransferase 5) (beta-3-gx-t5). [swissprot;acc:q9y2c3]	3631	B3GALT5	Divided		200.633	197.828	1.01418
	3639		Subtracted				2.805
beta-1,4 mannosyltransferase. [refseq;acc:nm_019109]	301	ALG1	Divided	High confidence	150.982	166.372	1.10193
	492		Subtracted				15.39
	4906		Divided	Low confidence	179.202	179.551	1.00195
	4915		Subtracted				0.349
beta-1-syntrophin (59 kda dystrophin-associated protein a1, basic component 1) (dapa1b) (tax interaction protein 43) (tip-43) (syntrophin 2) (bsyn2). [swissprot;acc:q13884]	2576	SNTB1	Divided	High confidence	213.422	213.75	1.00154
	2577		Subtracted				0.328
	3276		Divided	Low confidence	202.385	199.258	1.01569
	3284		Subtracted				3.127
beta-2-syntrophin (59 kda dystrophin-associated protein a1, basic component 2) (syntrophin 3) (snt3) (syntrophin-like) (sntl). [swissprot;acc:q13425]	2578	SNTB2	Divided	High confidence	213.422	213.75	1.00154
			Subtracted				0.328
	3277		Divided	Low confidence	202.385	199.258	1.01569
	3285		Subtracted				3.127
beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407]	50	ARRB1	Divided	High confidence	133	105	1.26667
	164		Subtracted				28
	439		Divided	Low confidence	194.237	187.689	1.03489
	487		Subtracted				6.548
beta-arrestin 2 (arrestin, beta 2). [swissprot;acc:p32121]	49	ARRB2	Divided	High confidence	133	105	1.26667
	163		Subtracted				28
	428		Divided	Low confidence	194.137	187.552	1.03511
	479		Subtracted				6.585
beta-carotene 15, 15'-dioxygenase; beta-carotene 15,15'-monooxygenase. [refseq;acc:nm_017429]	2178	BCMO1		High confidence	221.509	220.108	1.401
	2222		Divided				1.00637
	2986		Subtracted	Low confidence	203.19	199.882	3.308
	3074		Divided				1.01655
beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938]	2177	no value	Subtracted	High confidence	221.509	220.108	1.401
	2221		Divided				1.00637
	2985		Subtracted	Low confidence	203.19	199.882	3.308
	3073		Divided				1.01655
beta-catenin (pro2286). [swissprot;acc:p35222]	778	CTNNB1	Subtracted	High confidence	224.445	214.894	9.551
	801		Divided				1.04445
	4871		Subtracted	Low confidence	207.082	206.548	0.534

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.