MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1908 to 1957 of 3228 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	description	Hugo	red	green	network_comparison
1908	similar to cg7020 gene product (fragment). [sptrembl;acc:q96ib4]	DIP2B	191.415	193.394	1.01034
1909	calmegin precursor. [swissprot;acc:o14967]	CLGN	217.48	215.256	1.01033
1910	calnexin precursor (major histocompatibility complex class i antigen-binding protein p88) (p90) (ip90). [swissprot;acc:p27824]	CANX
1911	soluble liver antigen/liver pancreas antigen. [refseq;acc:nm_153825]	SEPSECS
1912	rna (guanine-7-) methyltransferase. [refseq;acc:nm_003799]	RNMT
1913	phospholipid scramblase 3 (pl scramblase 3) (ca(2+)-dependent phospholipid scramblase 3). [swissprot;acc:q9nry6]	no value	215.745	213.564	1.01021
1914	phospholipid scramblase 4 (pl scramblase 4) (ca(2+)-dependent phospholipid scramblase 4). [swissprot;acc:q9nrq2]	PLSCR4
1915	phospholipid scramblase 2 (pl scramblase 2) (ca(2+)-dependent phospholipid scramblase 2). [swissprot;acc:q9nry7]	PLSCR2	215.747	213.571	1.01019
1916	rh type c glycoprotein. [refseq;acc:nm_016321]	RHCG	196.88	198.88	1.01016
1917	p28 ing5. [refseq;acc:nm_032329]	ING5	215.848	218.039	1.01015
1918	endothelial-derived gene 1. [refseq;acc:nm_025205]	MED28	202.211	200.18
1919	histidyl-trna synthetase homolog (ec 6.1.1.21) (histidine--trna ligase homolog) (hisrs). [swissprot;acc:p49590]	HARS2	187.231	185.349
1920	histidyl-trna synthetase (ec 6.1.1.21) (histidine--trna ligase) (hisrs). [swissprot;acc:p12081]	HARS	187.292	185.413	1.01013
1921	5-methyltetrahydrofolate--homocysteine methyltransferase (ec 2.1.1.13) (methionine synthase, vitamin-b12 dependent) (ms). [swissprot;acc:q99707]	MTR	221.607	219.386	1.01012
1922	centaurin gamma 2. [swissprot;acc:q9upq3]	CENTG2	220.659	218.452	1.0101
1923	general vesicular transport factor p115 (transcytosis associated protein) (tap) (vesicle docking protein). [swissprot;acc:o60763]	USO1
1924	centaurin gamma 1. [swissprot;acc:q99490]	CENTG1
1925	centaurin gamma 3. [swissprot;acc:q96p47]	CENTG3
1926	rhesus blood group, b glycoprotein; rh type b glycoprotein. [refseq;acc:nm_020407]	RHBG	196.925	198.91	1.01008
1927	rhesus blood group-associated glycoprotein (erythrocyte plasma membrane 50 kda glycoprotein) (rh50a). [swissprot;acc:q02094]	RHAG	196.932	198.914	1.01006
1928	blood group rh(d) polypeptide (rhesus d antigen) (rhxiii) (rh polypeptide 2) (rhpii). [swissprot;acc:q02161]	RHD	196.964	198.935	1.01001
1929	enigma protein; lim domain protein. [refseq;acc:nm_005451]	no value	219.753	217.574
1930	blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577]		196.964	198.935
1931	eukaryotic translation initiation factor 3 subunit 7 (eif-3 zeta) (eif3 p66) (eif3d). [swissprot;acc:o15371]	EIF3D	219.753	217.574
1932	blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577]	no value	196.965	198.936
1933	ornithine carbamoyltransferase, mitochondrial precursor (ec 2.1.3.3) (otcase) (ornithine transcarbamylase). [swissprot;acc:p00480]	OTC	215.667	217.82	1.00998
1934	gamma adducin (adducin-like protein 70). [swissprot;acc:q9uey8]	ADD3	224.264	222.055	1.00995
1935	abhydrolase domain containing protein 2 (protein phps1-2). [swissprot;acc:p08910]	ABHD2	218.43	216.279
1936	creatine kinase, sarcomeric mitochondrial precursor (ec 2.7.3.2) (s- mtck) (mib-ck) (basic-type mitochondrial creatine kinase). [swissprot;acc:p17540]	CKMT2	198.3	196.347
1937	quaking isoform 6. [sptrembl;acc:q9p0x9]	QKI	218.43	216.279
1938	creatine kinase, ubiquitous mitochondrial precursor (ec 2.7.3.2) (u- mtck) (mia-ck) (acidic-type mitochondrial creatine kinase). [swissprot;acc:p12532]	no value	198.293	196.341	1.00994
1939	peptidyl prolyl isomerase h; cyclophilin h. [refseq;acc:nm_006347]	PPIH	198.258	196.319	1.00988
1940	creatine kinase, b chain (ec 2.7.3.2) (b-ck). [swissprot;acc:p12277]	CKB	198.19	196.252
1941	prp18 pre-mrna processing factor 18 homolog. [refseq;acc:nm_003675]	PRPF18	198.258	196.319
1942	j domain protein c21orf55. [swissprot;acc:q9nx36]	C21orf55	198.257		1.00987
1943	megf11 protein. [refseq;acc:nm_032445]	MEGF11	224.34	222.147
1944	megf10 protein. [refseq;acc:nm_032446]	MEGF10	224.341	222.148
1945	beta adducin (erythrocyte adducin beta subunit). [swissprot;acc:p35612]	ADD2	224.343	222.151
1946	nuclear factor, interleukin 3 regulated. [refseq;acc:nm_005384]	NFIL3	214.234	212.142	1.00986
1947	protein phosphatase inhibitor 2 (ipp-2). [swissprot;acc:p41236]	PPP1R2	125.845	127.083	1.00984
1948	15 kda selenoprotein precursor. [swissprot;acc:o60613]	no value	214.522	212.432
1949	rna-binding protein with multiple splicing (rbp-ms). [swissprot;acc:q93062]	RBPMS	218.794	216.663
1950	vacuolar protein sorting 18 (hvps18). [swissprot;acc:q9p253]	VPS18	215.847	213.747	1.00982
1951	trna isopentenylpyrophosphate transferase. [refseq;acc:nm_017646]	TRIT1	205.876	203.873
1952	importin alpha-1 subunit (karyopherin alpha-1 subunit) (srp1-beta) (rag cohort protein 2) (nucleoprotein interactor 1) (npi-1). [swissprot;acc:p52294]	KPNA1	211.647	213.724	1.00981
1953	type 1 protein phosphatase inhibitor. [refseq;acc:nm_025210]	PPP1R2P9	125.912	127.146	1.0098
1954	voltage-gated potassium channel beta-3 subunit (k+ channel beta-3 subunit) (kv-beta-3). [swissprot;acc:o43448]	KCNAB3	211.632	213.703	1.00979
1955	yip1 interacting factor homolog; yip1p-interacting factor; putative rab5-interacting protein; putative transmembrane protein 54tmp. [refseq;acc:nm_020470]	YIF1A	211.633		1.00978
1956	voltage-gated potassium channel beta-1 subunit (k+ channel beta-1 subunit) (kv-beta-1). [swissprot;acc:q14722]	KCNAB1
1957	similar to putative transmembrane protein; homolog of yeast golgi membrane protein yif1p (yip1p-interacting factor). [refseq;acc:nm_033557]	YIF1B

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.