MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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green	Filtered	description	red	Rank	Gene	Interaction Map	network_comparison	Value Type	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

green  : 0
Filtered  : 0
Network Comparison Type  : Subtracted

description	red	Rank	Interaction Map	network_comparison	Value Type
brca1 associated protein. [refseq;acc:nm_006768]	0	502	High confidence	0	Measured
					Ranked
					Squared
					Rooted
carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 6; macular dystrophy, corneal, 1; carbohydate sulfotransferase 6; corneal n-acetylglucosamine 6-sulfotransferase. [refseq;acc:nm_021615]	0.324024	826	Low confidence	0.324024	Squared
	6.08276	42		6.08276	Rooted
	37	648		37	Measured
carbohydrate (n-acetylglucosamine-6-o) sulfotransferase 2; carbohydrate (chondroitin 6/keratan) sulfotransferase 2. [refseq;acc:nm_004267]	0.324024	827		0.324024	Squared
	6.08276	43		6.08276	Rooted
	37	649		37	Measured
cobw-like protein. [refseq;acc:nm_018491]	0	839		0
					Ranked
					Squared
					Rooted
dok-like protein. [refseq;acc:nm_024872]	0.289941	467	High confidence	0.289941	Squared
	5.91608	74		5.91608	Rooted
	35	386		35	Measured
ero1-like. [refseq;acc:nm_014584]	1.59148	440		1.59148	Squared
	9.05539	38		9.05539	Rooted
	82	316		82	Measured
gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]	0	838	Low confidence	0
					Ranked
					Squared
					Rooted
gamma-glutamyltransferase. [sptrembl;acc:q14390]		841			Measured
					Ranked
					Squared
					Rooted
gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]		842			Measured
					Ranked
					Squared
					Rooted
gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]		837			Measured
					Ranked
					Squared
					Rooted
gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]		843			Measured
					Ranked
					Squared
					Rooted
h2a histone family, member j isoform 1. [refseq;acc:nm_018267]		501	High confidence		Measured
					Squared
					Rooted
histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]		495			Measured
					Squared
					Rooted
histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]		494			Measured
					Squared
					Rooted
histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]		497			Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.