MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Network Comparison Type	Value Type	Interaction Map	red	Filtered	green	network_comparison

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Showing element 836 to 885 of 66312 in total

Filtered  : 1

description	Rank	Hugo	Network Comparison Type	Value Type	Interaction Map	red	green	network_comparison
3 beta-hydroxy-delta 5-c27-steroid oxidoreductase. [refseq;acc:nm_025193]	3147	HSD3B7	Subtracted	Ranked	High confidence	0	0	0
				Squared
				Rooted
	3407			Measured	Low confidence	8082.12	8292.57	210.45
	3493		Divided					1.02604
3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	1073	no value		Squared		44737.4	42724.1	1.04712
	1252		Subtracted					2013.3
	1663		Divided	Ranked		197.872	193.866	1.02066
	1733		Subtracted					4.006
	2480			Rooted		73.0199	75.4487	2.4288
	2622		Divided					1.03326
	2756			Measured	High confidence	0.00001	0.00001	1
				Ranked
				Squared
				Rooted
			Subtracted	Measured		0	0	0
				Ranked
				Squared
				Rooted
	3403			Measured	Low confidence	8082.12	8292.57	210.45
	3487		Divided					1.02604
3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type i (3beta-hsd i) (trophoblast antigen fdo161g) [includes: 3-beta-hydroxy- delta(5)-steroid dehydrogenase (ec 1.1.1.145) (3-beta-hydroxy-5-ene steroid dehydrogenase) (progesterone reductase); steroid delta- isomerase (ec 5.3.3.1) (delta-5-3-ketosteroid isomerase)]. [swissprot;acc:p14060]	1075			Squared		44737.4	42724.1	1.04712
	1254		Subtracted					2013.3
	1665		Divided	Ranked		197.872	193.866	1.02066
	1735		Subtracted					4.006
	2483			Rooted		73.0199	75.4487	2.4288
	2624		Divided					1.03326
	2802			Measured	High confidence	0.00001	0.00001	1
				Ranked
				Squared
				Rooted
			Subtracted	Measured		0	0	0
				Ranked
				Squared
				Rooted
	3405			Measured	Low confidence	8082.12	8292.57	210.45
	3489		Divided					1.02604
3'(2'), 5'-bisphosphate nucleotidase 1; bisphosphate 3'-nucleotidase; bpntase; pap-inositol-1,4-phosphatase. [refseq;acc:nm_006085]	164	BPNT1	Subtracted	Ranked		209.954	221.607	11.653
	178		Divided					1.0555
	2650			Squared		37407.8	36053.6	1.03756
	3669		Subtracted					1354.2
	4603		Divided	Rooted		66.9425	65.5857	1.02069
	4696		Subtracted					1.3568
	4994		Divided	Measured		6922.79	6911.72	1.0016
	4995		Subtracted					11.07
3'-5' rna exonuclease; polynucleotide phosphorylase-like. [refseq;acc:nm_033109]	1268	PNPT1		Ranked		206.13	201.696	4.434
	1373		Divided					1.02198
	1388			Rooted		69.8381	72.4192	1.03696
	1715		Subtracted					2.5811
	2310		Divided	Measured		7602.32	7838.4	1.03105

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.