MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	Rank	Value Type	green	network_comparison	description	Network Comparison Type	Interaction Map	Filtered	red

Results: HTML CSV LaTeX

Showing element 451 to 500 of 19268 in total

Value Type  : Measured

Rank	green	network_comparison	description	Network Comparison Type	Interaction Map	Filtered	red
57	1729.7	500.43	udp-glucuronosyltransferase 2b15 precursor, microsomal (ec 2.4.1.17) (udpgt) (udpgth-3) (hlug4). [swissprot;acc:p54855]	Subtracted	High confidence	0	2230.13
	1973.79	383.35	zinc finger protein 32 (zinc finger protein kox30) (fragment). [swissprot;acc:p17041]		Low confidence		2357.14
	2664.55	1.63302	kh domain containing, rna binding, signal transduction associated 3; sam68-like phosphotyrosine protein, t-star. [refseq;acc:nm_006558]	Divided	High confidence	1	1631.67
	7600.25	1119.66	fos-related antigen 2. [swissprot;acc:p15408]	Subtracted	Low confidence		6480.59
	17572.7	1.13635	homeobox protein hox-b4 (hox-2f) (hox-2.6). [swissprot;acc:p17483]	Divided			15464.1
	24908.5	3997.5	ras-related gtp binding c; rag c protein. [refseq;acc:nm_022157]	Subtracted	High confidence		20911
58	81.2233	1.85588	40s ribosomal protein s26. [swissprot;acc:p02383]	Divided		0	150.741
	438.016	2.16672	tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702]		Low confidence		202.156
	1972.76	383.26	zinc finger protein 95 homolog (zfp-95). [swissprot;acc:q9y2l8]	Subtracted			2356.02
	2664.55	1.63302	kh domain containing, rna binding, signal transduction associated 1; gap-associated tyrosine phosphoprotein p62 (sam68). [refseq;acc:nm_006559]	Divided	High confidence	1	1631.67
	7600.61	1118.99	protein fosb (g0/g1 switch regulatory protein 3). [swissprot;acc:p53539]	Subtracted	Low confidence		6481.62
	12011.7	499.4	imp2 inner mitochondrial membrane protease-like; inner mitochondrial membrane peptidase 2 like. [refseq;acc:nm_032549]		High confidence	0	11512.3
	17572.7	1.13635	homeobox protein hox-c5 (hox-3d) (cp11). [swissprot;acc:q00444]	Divided	Low confidence	1	15464.1
	24908.5	3997.5	ras-related gtp binding b short isoform; gtp-binding protein ragb. [refseq;acc:nm_006064]	Subtracted	High confidence		20911
59	279.24	1.85328	f-actin capping protein alpha-2 subunit (capz alpha-2). [swissprot;acc:p47755]	Divided		0	150.673
	315.505	2.14473	nadph oxidase, ef hand calcium-binding domain 5. [refseq;acc:nm_024505]		Low confidence		147.107
	1972.55	383.25	zinc finger protein 80 (znfpt17). [swissprot;acc:p51504]	Subtracted			2355.8
	2664.55	1.63302	kh domain-containing, rna-binding, signal transduction-associated protein 2; sam68-like mammalian protein 1. [refseq;acc:nm_152688]	Divided	High confidence	1	1631.67
	7601.81	1116.76	fos-related antigen 1 (fra-1). [swissprot;acc:p15407]	Subtracted	Low confidence		6485.05
	12011.7	499.4	microsomal signal peptidase 18 kda subunit (ec 3.4.-.-) (spase 18 kda subunit) (spc18) (endopeptidase sp18). [swissprot;acc:p21378]		High confidence	0	11512.3
	17572.7	1.13635	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]	Divided	Low confidence	1	15464.1
	24908.5	3997.5	anillin, actin binding protein (scraps homolog, drosophila); anillin (drosophila scraps homolog), actin binding protein. [refseq;acc:nm_018685]	Subtracted	High confidence		20911
60	87.5499	1.8441	adapter-related protein complex 1 sigma 1b subunit (sigma-adaptin 1b) (adaptor protein complex ap-1 sigma-1b subunit) (golgi adaptor ha1/ap1 adaptin sigma-1b subunit) (clathrin assembly protein complex 1 sigma- 1b small chain) (sigma 1b subunit of ap-1 clathrin) (dc22). [swissprot;acc:p56377]	Divided		0	47.4756
	315.567	2.14463	nadph oxidase homolog 1 (nox-1) (noh-1) (nadh/nadph mitogenic oxidase subunit p65-mox) (mitogenic oxidase 1) (mox1). [swissprot;acc:q9y5s8]		Low confidence		147.143
	1972.44	383.23	zinc finger protein 187. [refseq;acc:nm_152736]	Subtracted			2355.67
	2765.82	1.6231	1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	Divided	High confidence	1	4489.19
	4827.7	475	tyrosine aminotransferase (ec 2.6.1.5) (l-tyrosine:2-oxoglutarate aminotransferase) (tat). [swissprot;acc:p17735]	Subtracted		0	5302.7
	12479.2	1108.2	tumor protein p53 inducible protein 3; quinone oxidoreductase homolog; p53-induced gene 3 protein. [refseq;acc:nm_004881]		Low confidence	1	11371
	12889.1	3882.4	ubiquitin activating enzyme e1-like protein. [refseq;acc:nm_006395]		High confidence		16771.5
	17572.7	1.13635	homeobox protein hox-d4 (hox-4b) (hox-5.1) (hho.c13). [swissprot;acc:p09016]	Divided	Low confidence		15464.1
61	151	2.09722	selenide,water dikinase 2 (ec 2.7.9.3) (selenophosphate synthetase 2) (selenium donor protein 2). [swissprot;acc:q99611]			0	72
	403.196	467.286	deltex homolog 1; hdx-1. [refseq;acc:nm_004416]	Subtracted	High confidence		870.482
	593.094	1.82804	glutathione s-transferase theta 2 (ec 2.5.1.18) (gst class-theta). [swissprot;acc:p30712]	Divided			324.442
	1972.44	383.23	zinc finger protein 302 (znf135-like) (znf140-like). [swissprot;acc:q9nr11]	Subtracted	Low confidence		2355.67
	2765.82	1.6231	glycogen phosphorylase, brain form (ec 2.4.1.1). [swissprot;acc:p11216]	Divided	High confidence	1	4489.19
	7680.25	1065.74	transcription factor jun-d. [swissprot;acc:p17535]	Subtracted	Low confidence		6614.51
	10307.5	3832	beta-arrestin 2 (arrestin, beta 2). [swissprot;acc:p32121]		High confidence		6475.5
	17572.7	1.13635	homeobox protein hox-b5 (hox-2a) (hho.c10) (hu-1). [swissprot;acc:p09067]	Divided	Low confidence		15464.1
62	384.407	1.82385	dipeptidyl peptidase 8 isoform 2; dipeptidyl peptidase 8. [refseq;acc:nm_017743]		High confidence	0	210.767
	977	465	putative phosphoglycerate mutase 3 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13). [swissprot;acc:q8n0y7]	Subtracted			1442
	1972.28	383.22	zinc finger protein zfp6 (fragment). [sptrembl;acc:q92967]		Low confidence		2355.5
	2765.82	1.6231	glycogen phosphorylase, liver form (ec 2.4.1.1). [swissprot;acc:p06737]	Divided	High confidence	1	4489.19
	4356	2.09222	anchor attachment protein 1; glycophosphatidylinositol anchor attachment 1; anchor attachment protein 1 (gaa1p, yeast) homolog. [refseq;acc:nm_003801]		Low confidence	0	2082
	7678.76	1065.34	transcription factor jun-b. [swissprot;acc:p17275]	Subtracted		1	6613.42
	10307.5	3832	beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407]		High confidence		6475.5
	17572.7	1.13635	homeobox protein hox-a5 (hox-1c). [swissprot;acc:p20719]	Divided	Low confidence		15464.1
63	56.278	1.80709	spir-2 protein (fragment). [sptrembl;acc:q8wwl2]		High confidence	0	31.1429
	75.6508	2.03842	laminin beta-1 chain precursor (laminin b1 chain). [swissprot;acc:p07942]		Low confidence		154.208
	977	465	phosphoglycerate mutase 1 (ec 5.4.2.1) (ec 5.4.2.4) (ec 3.1.3.13) (phosphoglycerate mutase isozyme b) (pgam-b) (bpg-dependent pgam 1). [swissprot;acc:p18669]	Subtracted	High confidence		1442
	1972.19	383.22	zinc finger protein 8 (zinc finger protein hf.18) (fragment). [swissprot;acc:p17098]		Low confidence		2355.41

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.