MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 3228 in total

Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1
red  : 0.00001
green  : 0.00001
network_comparison  : 1

Rank	description
3178	transcription initiation factor iie, beta subunit (tfiie-beta). [swissprot;acc:p29084]
3177	ergic-53 protein precursor (er-golgi intermediate compartment 53 kda protein) (lectin, mannose-binding 1) (gp58) (intracellular mannose specific lectin mr60). [swissprot;acc:p49257]
3176	phosphate carrier protein, mitochondrial precursor (ptp). [swissprot;acc:q00325]
3175	tubulin alpha-3/alpha-7 chain (alpha-tubulin 3/7). [swissprot;acc:p05214]
3174	transmembrane 9 superfamily protein member 3 precursor (sm-11044 binding protein) (ep70-p-iso). [swissprot;acc:q9hd45]
3173	phosphoinositide-3-kinase, class 3; vps34; phosphatidylinositol 3-kinase, class 3. [refseq;acc:nm_002647]
3172	hormone sensitive lipase (ec 3.1.1.-) (hsl). [swissprot;acc:q05469]
3171	cyclin t2. [swissprot;acc:o60583]
3170	ecotropic virus integration 1 site protein. [swissprot;acc:q03112]
3169	transcriptional repressor nf-x1 (ec 6.3.2.-) (nuclear transcription factor, x box-binding, 1). [swissprot;acc:q12986]
3168	cop-coated vesicle membrane protein p24 precursor (p24a). [swissprot;acc:q15363]
3167	centromere/kinetochore protein zw10 homolog. [swissprot;acc:o43264]
3166	myotubularin-related protein 2 (ec 3.1.3.-). [swissprot;acc:q13614]
3165	gpi transamidase component pig-s (phosphatidylinositol-glycan biosynthesis, class s protein). [swissprot;acc:q96s52]
3164	transcription factor ap-2 gamma (ap2-gamma) (activating enhancer- binding protein 2 gamma) (transcription factor erf-1). [swissprot;acc:q92754]
3163	ccr4-not transcription complex, subunit 3; not3 (negative regulator of transcription 3, yeast) homolog. [refseq;acc:nm_014516]
3162	phosphatidylethanolamine-binding protein (pebp) (prostatic binding protein) (hcnppp) (neuropolypeptide h3) (raf kinase inhibitor protein) (rkip) [contains: hippocampal cholinergic neurostimulating peptide (hcnp)]. [swissprot;acc:p30086]
3161	brca1 associated protein. [refseq;acc:nm_006768]
3160	cyclin k. [swissprot;acc:o75909]
3159	trinucleotide repeat containing 6; edie; gw182 autoantigen. [refseq;acc:nm_014494]
3158	integrin alpha-6 precursor (vla-6) (cd49f). [swissprot;acc:p23229]
3157	vesicle transport-related protein isoform a; vesicle transport-related protein. [refseq;acc:nm_016106]
3156	tektin 2 (tektin-t) (testicular tektin b1-like protein). [swissprot;acc:q9uif3]
3155	transforming growth factor beta 2 precursor (tgf-beta 2) (glioblastoma-derived t-cell suppressor factor) (g-tsf) (bsc-1 cell growth inhibitor) (polyergin) (cetermin). [swissprot;acc:p08112]
3154	nucleoporin 50 kda (nuclear pore-associated protein 60 kda-like) (pro1146). [swissprot;acc:q9ukx7]
3153	leucine rich repeat (in flii) interacting protein 2. [refseq;acc:nm_006309]
3152	histone deacetylase 6 (hd6). [swissprot;acc:q9ubn7]
3151	dna mismatch repair protein msh2. [swissprot;acc:p43246]
3150	cysteine-rich secretory protein-3 precursor (crisp-3) (sgp28 protein). [swissprot;acc:p54108]
3149	bromodomain and phd finger-containing protein 3 (fragment). [swissprot;acc:q9uld4]
3148	muts protein homolog 5. [swissprot;acc:o43196]
3147	3 beta-hydroxy-delta 5-c27-steroid oxidoreductase. [refseq;acc:nm_025193]
3146	putative nadh oxidoreductase complex i subunit homolog. [sptrembl;acc:q96q80]
3145	beta-ureidopropionase (ec 3.5.1.6) (beta-alanine synthase) (n-carbamoyl-beta-alanine amidohydrolase) (bup-1). [swissprot;acc:q9ubr1]
3144	high mobility group protein 1-like 10 (hmg-1l10). [swissprot;acc:q9ugv6]
3143	prkca-binding protein (protein kinase c-alpha binding protein) (protein interacting with c kinase 1). [swissprot;acc:q9nrd5]
3142	protein kinase c and casein kinase substrate in neurons protein 2. [swissprot;acc:q9unf0]
3141	tubulin tyrosine ligase-like protein 1. [swissprot;acc:o95922]
3140	myosin heavy chain, nonmuscle type a (cellular myosin heavy chain, type a) (nonmuscle myosin heavy chain-a) (nmmhc-a). [swissprot;acc:p35579]
3139	bromodomain-containing protein 1 (br140-like protein). [swissprot;acc:o95696]
3138	hcdi protein. [refseq;acc:nm_020195]
3137	serine/threonine-protein kinase kkialre (ec 2.7.1.-) (cyclin-dependent kinase-like 1). [swissprot;acc:q00532]
3136	vaccinia related kinase 1; vaccinia-related kinase-1. [refseq;acc:nm_003384]
3135	protein transport protein sec23a (sec23-related protein a). [swissprot;acc:q15436]
3134	rab geranylgeranyltransferase alpha subunit (ec 2.5.1.-) (rab geranyl- geranyltransferase alpha subunit) (rab gg transferase alpha) (rab ggtase alpha). [swissprot;acc:q92696]
3133	ngd5 protein homolog (cgi-53). [swissprot;acc:q9y366]
3132	r3h domain (binds single-stranded nucleic acids) containing-like. [refseq;acc:nm_178491]
3131	protein c20orf24 (rab5-interacting protein) (rip5) (pnas-11). [swissprot;acc:q9buv8]
3130	prefoldin subunit 4 (protein c-1). [swissprot;acc:q9nqp4]
3129	cleavage stimulation factor, 50 kda subunit (cstf 50 kda subunit) (cf-1 50 kda subunit). [swissprot;acc:q05048]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.