MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Value Type	Filtered	Interaction Map	green	red	Network Comparison Type	network_comparison

Results: HTML CSV LaTeX

Showing element 451 to 500 of 66312 in total

Filtered  : 1

description	Rank	Value Type	Interaction Map	green	red	Network Comparison Type	network_comparison
26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998]	2321	Ranked	Low confidence	194.732	198.366	Divided	1.01866
	2394		High confidence	219.014	218.192	Subtracted	0.822
	2395					Divided	1.00377
	2407		Low confidence	194.732	198.366	Subtracted	3.634
	4819	Squared		47560.6	47959.2		398.6
	4841					Divided	1.00838
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210]	453		High confidence	53788.1	59318.4	Subtracted	5530.3
	797		Low confidence	44326.9	46535.2		2208.3
	864					Divided	1.04982
	1637	Ranked	High confidence	199.408	202.358		1.01479
	1682					Subtracted	2.95
	1721	Squared		53788.1	59318.4	Divided	1.10282
	1772	Rooted		76.9113	74.9362	Subtracted	1.9751
	2059					Divided	1.02636
	2149	Ranked	Low confidence	197.22	200.982	Subtracted	3.762
	2163					Divided	1.01908
	2260	Rooted		74.792	72.3171	Subtracted	2.4749
	2297					Divided	1.03422
	2602	Measured	High confidence	9234.09	9150.44	Subtracted	83.65
	2651					Divided	1.00914
	2944		Low confidence	8314.51	8088.94	Subtracted	225.57
	3044					Divided	1.02789
26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524]	1280	Squared	High confidence	30113.9	27176.8	Subtracted	2937.1
	1577	Measured		6349.04	5923.66	Divided	1.07181
	1599					Subtracted	425.38
	1630	Squared		30113.9	27176.8	Divided	1.10807
	1944	Rooted		64.5421	62.7515		1.02853
	1968					Subtracted	1.7906
	2478	Ranked		216.801	216.177	Divided	1.00289
	2486					Subtracted	0.624
	2526	Measured	Low confidence	8326.51	8088.12		238.39
	2711					Divided	1.02947
	3092	Rooted		74.8438	72.5509	Subtracted	2.2929
	3167					Divided	1.0316
	3429	Squared		44345.7	45773.6	Subtracted	1427.9
	3515	Ranked		197.374	200.312	Divided	1.01489
	3521					Subtracted	2.938
	3537	Squared		44345.7	45773.6	Divided	1.0322
26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [swissprot;acc:q99460]	830	Ranked		199.229	204.36	Subtracted	5.131
	857					Divided	1.02575
	1146	Squared		42544.1	44506		1.04611
	1162	Rooted		73.5808	70.8788		1.03812
	1182	Squared	High confidence	29969	26860.7	Subtracted	3108.3
	1280	Rooted	Low confidence	73.5808	70.8788		2.702
	1379	Squared		42544.1	44506		1961.9
	1476		High confidence	29969	26860.7	Divided	1.11572
	1862	Measured		6195.48	5826	Subtracted	369.48
	1883					Divided	1.06342
	2129	Rooted		63.5033	62.0038		1.02418
	2140					Subtracted	1.4995

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.