MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	description	Value Type	Rank	Filtered	Network Comparison Type	Interaction Map	network_comparison	green	red

Results: HTML CSV LaTeX

Showing element 851 to 900 of 3730 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence

description	Rank	Filtered	network_comparison	green	red
dc11 protein. [refseq;acc:nm_020186]	2489	1	1.00284	195.08	194.527
dc12 protein. [refseq;acc:nm_020187]	2774		1	0.00001	0.00001
dead (asp-glu-ala-asp) box polypeptide 31 isoform 1; dead/dexh helicase ddx31. [refseq;acc:nm_022779]	527		1.06871	232.579	248.56
dead (asp-glu-ala-asp) box polypeptide 39 isoform 1; nuclear rna helicase, decd variant of dead box family. [refseq;acc:nm_005804]	1140		1.02731	212.675	218.484
dead (asp-glu-ala-asp) box polypeptide 47; hqp0256 protein. [refseq;acc:nm_016355]	372	0	1.04489	12402.7	11869.9
	1385	1	1.02148	213.875	218.47
dead-box protein 4 (vasa homolog). [swissprot;acc:q9nqi0]	1689		1.01383	225.163	228.277
dead-box protein abstrakt homolog. [swissprot;acc:q9ujv9]	176	0	1.13359	11528	13068
	634	1	1.05958	213.786	226.523
dead-box protein. [refseq;acc:nm_018665]	58	0	1.36296	14486	10628.3
	2012	1	1.00913	191.766	193.517
dead/h (asp-glu-ala-asp/his) box polypeptide 11; dead/h box-11 (chl1-related helicase gene-1); yeast chl1 homolog. [refseq;acc:nm_030655]	326	0	1.05779	11295.6	11948.4
	1720	1	1.01322	189.679	187.205
defender against cell death 1 (dad-1). [swissprot;acc:p46966]	1740		1.01289	209.258	206.595
deformed epidermal autoregulatory factor 1 homolog (nuclear deaf-1 related transcriptional regulator) (nudr) (suppressin) (zinc finger mynd domain containing protein 5). [swissprot;acc:o75398]	920		1.0372	245.547	236.741
dehydrodolichyl diphosphate synthase. [refseq;acc:nm_024887]	2275		1.00541	208.44	207.319
delta 1-pyrroline-5-carboxylate synthetase (p5cs) [includes: glutamate 5-kinase (ec 2.7.2.11) (gamma-glutamyl kinase) (gk); gamma-glutamyl phosphate reductase (gpr) (ec 1.2.1.41) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase)]. [swissprot;acc:p54886]	2305		1.00509	218.498	217.392
delta(14)-sterol reductase (ec 1.3.1.70) (c-14 sterol reductase) (sterol c14-reductase) (delta14-sr) (transmembrane 7 superfamily member 2) (another new gene 1) (putative sterol reductase sr-1). [swissprot;acc:o76062]	1901		1.01034	193.39	191.411
delta-aminolevulinic acid dehydratase (ec 4.2.1.24) (porphobilinogen synthase) (aladh). [swissprot;acc:p13716]	2252		1.00605	218.498	217.185
delta-interacting protein a (hepatitis delta antigen interacting protein a). [swissprot;acc:q15834]	2097		1.00745	213.39	214.979
delta-sarcoglycan (sg-delta) (35 kda dystrophin-associated glycoprotein) (35dag). [swissprot;acc:q92629]	1178		1.02593	212.672	218.186
delta3,5-delta2,4-dienoyl-coa isomerase, mitochondrial precursor (ec 5.3.3.-). [swissprot;acc:q13011]	667		1.0577	216.576	229.072
deltex 2. [refseq;acc:nm_020892]	110		1.2459	267.393	333.144
deltex homolog 1; hdx-1. [refseq;acc:nm_004416]	80	0	1.27636	11617.9	9102.34
	111	1	1.24563	267.274	332.925
dendritic cell protein. [refseq;acc:nm_006360]	713		1.05402	211.685	223.121
density-regulated protein (drp) (drp1 protein) (smooth muscle cell associated protein-3) (smap-3). [swissprot;acc:o43583]	267		1.11121	267.88	241.07
deoxycytidylate deaminase (ec 3.5.4.12) (dcmp deaminase). [swissprot;acc:p32321]	779		1.04826	241.641	230.516
deoxyhypusine synthase (ec 2.5.1.46) (dhs). [swissprot;acc:p49366]	2755		1.00001	212.401	212.403
deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]	322		1.09948	78.8995	86.7483
deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (ec 3.6.1.23) (dutpase) (dutp pyrophosphatase). [swissprot;acc:p33316]	1430		1.02037	190.925	187.114
destrin (actin-depolymerizing factor) (adf). [swissprot;acc:p18282]	2229		1.00634	219.336	217.955
developmentally regulated gtp-binding protein 1 (drg 1). [swissprot;acc:q9y295]	2762		1	0.00001	0.00001
developmentally regulated gtp-binding protein 2 (drg 2). [swissprot;acc:p55039]	3092
dgcr14 protein (digeorge syndrome critical region 14) (es2 protein). [swissprot;acc:q96df8]	174		1.17133	286	335
dgcr8 protein (digeorge syndrome critical region 8). [swissprot;acc:q8wyq5]	3006		1	0.00001	0.00001
di-ras2. [refseq;acc:nm_017594]	892		1.03907	204.055	212.028
dihydrofolate reductase (ec 1.5.1.3). [swissprot;acc:p00374]	164	0	1.14975	10412.4	11971.7
	1591	1	1.01621	228.769	225.119
dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (ec 2.3.1.12) (e2) (pdc-e2) (70 kda mitochondrial autoantigen of primary biliary cirrhosis) (pbc) (m2 antigen complex 70 kda subunit). [swissprot;acc:p10515]	1298		1.02384	211.404	206.482
dihydrolipoamide dehydrogenase, mitochondrial precursor (ec 1.8.1.4) (glycine cleavage system l protein). [swissprot;acc:p09622]	1039		1.03137	214.236	207.719
dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor (ec 2.3.1.61) (e2) (e2k). [swissprot;acc:p36957]	1462		1.0196	209.851	205.817
dihydroorotate dehydrogenase, mitochondrial precursor (ec 1.3.3.1) (dihydroorotate oxidase) (dhodehase) (fragment). [swissprot;acc:q02127]	2392		1.00388	215.799	214.966
dihydropyrimidine dehydrogenase [nadp+] precursor (ec 1.3.1.2) (dpd) (dhpdhase) (dihydrouracil dehydrogenase) (dihydrothymine dehydrogenase). [swissprot;acc:q12882]	344	0	1.05116	10027.6	10540.6
	1009	1	1.03288	221.823	229.116
dimeric dihydrodiol dehydrogenase; 3-deoxyglucosone reductase. [refseq;acc:nm_014475]	2213		1.00642	211.475	210.127
dimethylaniline monooxygenase [n-oxide forming] 1 (ec 1.14.13.8) (fetal hepatic flavin-containing monooxygenase 1) (fmo 1) (dimethylaniline oxidase 1). [swissprot;acc:q01740]	2288		1.00533	215.458	216.607
dimethylaniline monooxygenase [n-oxide forming] 2 (ec 1.14.13.8) (pulmonary flavin-containing monooxygenase 2) (fmo 2) (dimethylaniline oxidase 2) (fmo 1b1). [swissprot;acc:q99518]	2286		1.00535	215.456	216.608
dimethylaniline monooxygenase [n-oxide forming] 3 (ec 1.14.13.8) (hepatic flavin-containing monooxygenase 3) (fmo 3) (dimethylaniline oxidase 3) (fmo form 2) (fmo ii). [swissprot;acc:p31513]	103	0	1.21815	9130.38	7495.26
	2276	1	1.00541	215.448	216.613

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.