MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2175 to 2224 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	red	green	network_comparison
gamma-aminobutyric-acid receptor epsilon subunit precursor (gaba(a) receptor). [swissprot;acc:p78334]	626	GABRE	Divided	214.256	202.14	1.05994
	660		Subtracted			12.116
gamma-aminobutyric-acid receptor gamma-1 subunit precursor (gaba(a) receptor). [swissprot;acc:q8n1c3]	620	GABRG1	Divided			1.05994
	655		Subtracted			12.116
gamma-aminobutyric-acid receptor gamma-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p18507]	623	GABRG2	Divided			1.05994
	658		Subtracted			12.116
gamma-aminobutyric-acid receptor gamma-3 subunit precursor (gaba(a) receptor). [swissprot;acc:q99928]	618	GABRG3	Divided		202.139	1.05994
	651		Subtracted			12.117
gamma-butyrobetaine,2-oxoglutarate dioxygenase (ec 1.14.11.1) (gamma-butyrobetaine hydroxylase) (gamma-bbh). [swissprot;acc:o75936]	1842	BBOX1	Divided	212.455	210.113	1.01115
	1854		Subtracted			2.342
gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284]	3101	no value	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
gamma-sarcoglycan (gamma-sg) (35 kda dystrophin-associated glycoprotein) (35dag). [swissprot;acc:q13326]	1156	SGCG		218.186	212.672	5.514
	1181		Divided			1.02593
gamma-snap-associated factor 1; rab11-interacting protein. [refseq;acc:nm_015470]	1783	RAB11FIP5	Subtracted	220.462	217.926	2.536
	1817		Divided			1.01164
gamma-soluble nsf attachment protein (snap-gamma) (n-ethylmaleimide- sensitive factor attachment protein, gamma). [swissprot;acc:q99747]	110	NAPG	Subtracted	209.299	249.187	39.888
	166		Divided			1.19058
ganglioside-induced differentiation-associated protein 1-like 1. [refseq;acc:nm_024034]	1101	GDAP1L1	Subtracted	218.484	212.675	5.809
	1139		Divided			1.02731
ganglioside-induced differentiation-associated protein 1. [refseq;acc:nm_018972]	1103	GDAP1	Subtracted			5.809
	1141		Divided			1.02731
gastricsin precursor (ec 3.4.23.3) (pepsinogen c). [swissprot;acc:p20142]	2435	PGC	Subtracted	235.812	235.088	0.724
	2470		Divided			1.00308
gbp protein isoform a. [refseq;acc:nm_017870]	21	TMEM132A	Subtracted	325.586	256.492	69.094
	47		Divided			1.26938
gc-rich sequence dna-binding factor homolog. [swissprot;acc:q9y5b6]	2532	C21orf66	Subtracted	217.144	216.699	0.445
	2539		Divided			1.00205
gcn5-like protein 1 (rt14 protein). [swissprot;acc:p78537]	979	BLOC1S1		202.027	195.386	1.03399
	1023		Subtracted			6.641
gdp-fucose protein o-fucosyltransferase 1 precursor (ec 2.4.1.221) (peptide o-fucosyltransferase) (o-fuct-1). [swissprot;acc:q9h488]	3125	POFUT1	Divided	0.00001	0.00001	1
			Subtracted	0	0	0
gdp-mannose pyrophosphorylase a; mannose-1-phosphate guanylyltransferase (gdp). [refseq;acc:nm_013335]	1858	GMPPA		222.842	225.17	2.328
	1894		Divided			1.01045
gdp-mannose pyrophosphorylase b isoform 1; mannose-1-phosphate guanylyltransferase; amphoterin induced gene 3. [refseq;acc:nm_013334]	1857	GMPPB	Subtracted			2.328
	1893		Divided			1.01045
general control of amino acid synthesis protein 5-like 2 (ec 2.3.1.-) (histone acetyltransferase gcn5) (hsgcn5). [swissprot;acc:q92830]	2732	GCN5L2		202.233	202.175	1.00029
			Subtracted			0.058
general vesicular transport factor p115 (transcytosis associated protein) (tap) (vesicle docking protein). [swissprot;acc:o60763]	1890	USO1		220.659	218.452	2.207
	1923		Divided			1.0101
geranylgeranyl pyrophosphate synthetase (ggpp synthetase) (ggppsase) (geranylgeranyl diphosphate synthase) [includes: dimethylallyltransferase (ec 2.5.1.1); geranyltranstransferase (ec 2.5.1.10); farnesyltranstransferase (ec 2.5.1.29)]. [swissprot;acc:o95749]	2520	GGPS1	Subtracted	236.51	236.008	0.502
	2536		Divided			1.00213
geranylgeranyl transferase type i beta subunit (ec 2.5.1.-) (type i protein geranyl-geranyltransferase beta subunit) (ggtase-i-beta). [swissprot;acc:p53609]	1358	PGGT1B	Subtracted	225.039	229.573	4.534
	1438		Divided			1.02015
geranylgeranyl transferase type ii beta subunit (ec 2.5.1.-) (rab geranylgeranyltransferase beta subunit) (rab geranyl- geranyltransferase beta subunit) (rab gg transferase beta) (rab ggtase beta). [swissprot;acc:p53611]	2963	RABGGTB		0.00001	0.00001	1
			Subtracted	0	0	0
germ cell specific y-box binding protein; contrin. [refseq;acc:nm_015982]	2679	YBX2		208.438	208.635	0.197
	2685		Divided			1.00095
germ cell-less. [refseq;acc:nm_022471]	1780	no value		206.335	203.877	1.01206
	1804		Subtracted			2.458

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.