MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Network Comparison Type	Rank	Gene	Hugo	Value Type	description	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 412 to 461 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0
green  : 0

Rank	Hugo	Value Type	description
2858	RYK	Rooted	tyrosine-protein kinase ryk precursor (ec 2.7.1.112). [swissprot;acc:p34925]
2859	NKX6-1	Measured	homeobox protein nkx-6.1. [swissprot;acc:p78426]
		Ranked
		Squared
		Rooted
2860	no value	Measured	importin 9. [refseq;acc:nm_018085]
		Ranked
		Squared
		Rooted
2861	GNPDA2	Measured	glucosamine-6-phosphate isomerase. [refseq;acc:nm_138335]
		Ranked
		Squared
		Rooted
2862	SDC3	Measured	syndecan-3 (synd3). [swissprot;acc:o75056]
		Ranked
		Squared
		Rooted
2863	no value	Measured	high-glucose-regulated protein 8 (ny-ren-2 antigen). [swissprot;acc:q9y5a9]
		Ranked
		Squared
		Rooted
2864	MAGOH	Measured	mago nashi protein homolog. [swissprot;acc:p50606]
		Ranked
		Squared
		Rooted
2865	TAL1	Measured	t-cell acute lymphocytic leukemia-1 protein (tal-1 protein) (stem cell protein) (t-cell leukemia/lymphoma-5 protein). [swissprot;acc:p17542]
		Ranked
		Squared
		Rooted
2866	STX5	Measured	syntaxin 5. [swissprot;acc:q13190]
		Ranked
		Squared
		Rooted
2867	no value	Measured	sh3 adapter protein spin90 (sh3 protein interacting with nck, 90 kda) (vaca-interacting protein, 54 kda) (vip54) (af3p21) (diaphanous protein interacting protein) (dia interacting protein-1) (dip-1). [swissprot;acc:q9nzq3]
		Ranked
		Squared
		Rooted
2868	SNORA67	Measured	eukaryotic initiation factor 4a-i (eif-4a-i) (eif4a-i). [swissprot;acc:p04765]
		Ranked
		Squared
		Rooted
2869	PRPSAP1	Measured	phosphoribosyl pyrophosphate synthetase-associated protein 1 (prpp synthetase-associated protein 1) (39 kda phosphoribosypyrophosphate synthetase-associated protein) (pap39). [swissprot;acc:q14558]
		Ranked
		Squared
		Rooted
2870	SH2B2	Measured	adaptor protein with pleckstrin homology and src homology 2 domains. [refseq;acc:nm_020979]
		Ranked
		Squared
		Rooted
2871	VPS28	Measured	vps28 protein homolog. [swissprot;acc:q9uk41]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.