MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Filtered	Value Type	green	Rank	Gene	Interaction Map	network_comparison	description	red	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Filtered  : 0
Value Type  : Measured

green	Rank	Interaction Map	network_comparison	description	red	Network Comparison Type
322.947	148	Low confidence	1.26947	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]	409.972	Divided
	469		87.025			Subtracted
323.433	150		1.26852	williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]	410.28	Divided
	470		86.847			Subtracted
323.685	151		1.26808	williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]	410.457	Divided
	471		86.772			Subtracted
327.517	55	High confidence	1.92644	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]	630.942	Divided
	103		303.425			Subtracted
330.189	54		1.93484	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	638.862	Divided
	101		308.673			Subtracted
335	133		1.32937	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]	252	Divided
	314		83			Subtracted
336.584	143	Low confidence	1.28908	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	261.105	Divided
	157	High confidence
	319		75.479			Subtracted
	497	Low confidence
339.154	207	High confidence	1.19069	cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]	403.827	Divided
	331		64.673			Subtracted
339.779	485	Low confidence	1.06422	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	361.601	Divided
	733		21.822			Subtracted
346.751	134	High confidence	1.32862	mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362]	260.986	Divided
	309		85.765			Subtracted
351.772	68		1.76802	protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981]	198.964	Divided
	209		152.808			Subtracted
352.75	71		1.75762	ubiquitin protein ligase. [refseq;acc:nm_130466]	620	Divided
	119		267.25			Subtracted
354.349	318	Low confidence	1.16138	poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366]	305.111	Divided
	599		49.238			Subtracted
359.631	120	High confidence	1.37479	signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556]	494.417	Divided
	238		134.786			Subtracted
359.98	382		1.04852	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	377.445	Divided
	433		17.465			Subtracted
362.023	383		1.04825	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	379.489	Divided
	432		17.466			Subtracted
362.955	101	Low confidence	1.47569	60s ribosomal protein l37a. [swissprot;acc:p12751]	535.61	Divided
	301		172.655			Subtracted
363	203	High confidence	1.19408	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]	304	Divided
	296	Low confidence
	343	High confidence	59			Subtracted
	555	Low confidence
368.317	229	High confidence	1.14829	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]	320.752	Divided
	370		47.565			Subtracted
369.011	227		1.14972	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]	424.258	Divided
	349		55.247			Subtracted
372.961	145		1.29544	likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033]	287.903	Divided
	312		85.058			Subtracted
375.343	179	Low confidence	1.21433	alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]	455.789	Divided
	481		80.446			Subtracted
377.574	146	High confidence	1.29466	cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2]	291.639	Divided
	308		85.935			Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.