MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Network Comparison Type	Gene	Hugo	Value Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1963 to 2012 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Network Comparison Type	Hugo	Interaction Map	red	network_comparison	green
bet5 homolog (multiple myeloma protein 2) (mum-2). [swissprot;acc:q9y5r8]	1058	Divided	TRAPPC1	Low confidence	198.804	1.02401	194.142
	1093	Subtracted				4.662
beta adducin (erythrocyte adducin beta subunit). [swissprot;acc:p35612]	1448		ADD2		205.847	4.27	201.577
	1549	Divided				1.02118
	1897	Subtracted		High confidence	224.343	2.192	222.151
	1945	Divided				1.00987
beta enolase (ec 4.2.1.11) (2-phospho-d-glycerate hydro-lyase) (skeletal muscle enolase) (mse) (enolase 3). [swissprot;acc:p13929]	2361		ENO3		207.186	1.00415	208.046
	2364	Subtracted				0.86
	4628	Divided		Low confidence	201.961	1.00667	200.622
	4633	Subtracted				1.339
beta tubulin 1, class vi. [refseq;acc:nm_030773]	2985	Divided	TUBB1		200.1	1.01678	196.798
	3000	Subtracted				3.302
beta-1,3-galactosyltransferase 5 (ec 2.4.1.-) (beta-1,3-galtase 5) (beta3gal-t5) (b3gal-t5) (udp-galactose:beta-n-acetylglucosamine beta- 1,3-galactosyltransferase 5) (udp-gal:beta-glcnac beta-1,3- galactosyltransferase 5) (beta-3-gx-t5). [swissprot;acc:q9y2c3]	3631	Divided	B3GALT5		200.633	1.01418	197.828
	3639	Subtracted				2.805
beta-1,4 mannosyltransferase. [refseq;acc:nm_019109]	301	Divided	ALG1	High confidence	150.982	1.10193	166.372
	492	Subtracted				15.39
	4906	Divided		Low confidence	179.202	1.00195	179.551
	4915	Subtracted				0.349
beta-1-syntrophin (59 kda dystrophin-associated protein a1, basic component 1) (dapa1b) (tax interaction protein 43) (tip-43) (syntrophin 2) (bsyn2). [swissprot;acc:q13884]	2576	Divided	SNTB1	High confidence	213.422	1.00154	213.75
	2577	Subtracted				0.328
	3276	Divided		Low confidence	202.385	1.01569	199.258
	3284	Subtracted				3.127
beta-2-syntrophin (59 kda dystrophin-associated protein a1, basic component 2) (syntrophin 3) (snt3) (syntrophin-like) (sntl). [swissprot;acc:q13425]	2578	Divided	SNTB2	High confidence	213.422	1.00154	213.75
		Subtracted				0.328
	3277	Divided		Low confidence	202.385	1.01569	199.258
	3285	Subtracted				3.127
beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407]	50	Divided	ARRB1	High confidence	133	1.26667	105
	164	Subtracted				28
	439	Divided		Low confidence	194.237	1.03489	187.689
	487	Subtracted				6.548
beta-arrestin 2 (arrestin, beta 2). [swissprot;acc:p32121]	49	Divided	ARRB2	High confidence	133	1.26667	105
	163	Subtracted				28
	428	Divided		Low confidence	194.137	1.03511	187.552
	479	Subtracted				6.585
beta-carotene 15, 15'-dioxygenase; beta-carotene 15,15'-monooxygenase. [refseq;acc:nm_017429]	2178		BCMO1	High confidence	221.509	1.401	220.108
	2222	Divided				1.00637
	2986	Subtracted		Low confidence	203.19	3.308	199.882
	3074	Divided				1.01655
beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938]	2177	Subtracted	no value	High confidence	221.509	1.401	220.108
	2221	Divided				1.00637
	2985	Subtracted		Low confidence	203.19	3.308	199.882
	3073	Divided				1.01655
beta-catenin (pro2286). [swissprot;acc:p35222]	778	Subtracted	CTNNB1	High confidence	224.445	9.551	214.894
	801	Divided				1.04445
	4871	Subtracted		Low confidence	207.082	0.534	206.548
	4878	Divided				1.00259
beta-centractin (actin-related protein 1b) (arp1b). [swissprot;acc:p42025]	1482	Subtracted	ACTR1B	High confidence	225.148	3.971	221.177
	1510	Divided				1.01795
	3620			Low confidence	198.688	1.01424	195.899
	3655	Subtracted				2.789

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.