MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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green	description	red	Filtered	network_comparison	Value Type	Gene	Interaction Map	Rank	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 501 to 550 of 2121 in total

green  : 0
red  : 0
Filtered  : 1
network_comparison  : 0
Interaction Map  : High confidence
Network Comparison Type  : Subtracted

description	Value Type	Rank
eukaryotic initiation factor 4a-ii (eif-4a-ii) (eif4a-ii). [swissprot;acc:q14240]	Measured	2888
	Ranked
	Squared
	Rooted
exocyst complex component exo70. [swissprot;acc:q9upt5]	Measured	2781
	Ranked
	Squared
	Rooted
ezrin-binding partner pace-1 isoform 1. [refseq;acc:nm_020423]	Measured	3228
	Ranked
	Squared
	Rooted
fatty aldehyde dehydrogenase (ec 1.2.1.3) (aldehyde dehydrogenase, microsomal) (aldh class 3). [swissprot;acc:p51648]	Measured	3181
	Ranked
	Squared
	Rooted
ferrochelatase, mitochondrial precursor (ec 4.99.1.1) (protoheme ferro-lyase) (heme synthetase). [swissprot;acc:p22830]	Measured	3185
	Ranked
	Squared
	Rooted
fibrillin 1 precursor. [swissprot;acc:p35555]	Measured	2844
	Ranked
	Squared
	Rooted
fibrillin 2 precursor. [swissprot;acc:p35556]	Measured	2955
	Ranked
	Squared
	Rooted
fibrillin 3. [refseq;acc:nm_032447]	Measured	2939
	Ranked
	Squared
	Rooted
flap endonuclease-1 (ec 3.-.-.-) (maturation factor 1) (mf1). [swissprot;acc:p39748]	Measured	2831
	Ranked
	Squared
	Rooted
fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075]	Measured	2907
	Ranked
	Squared
	Rooted
fructose-bisphosphate aldolase b (ec 4.1.2.13) (liver-type aldolase). [swissprot;acc:p05062]	Measured	2973
	Ranked
	Squared
	Rooted
fructose-bisphosphate aldolase c (ec 4.1.2.13) (brain-type aldolase). [swissprot;acc:p09972]	Measured	3087
	Ranked
	Squared
	Rooted
fyve-finger-containing rab5 effector protein rabenosyn-5. [refseq;acc:nm_022340]	Measured	2998
	Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.