MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Network Comparison Type	Hugo	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 101 to 150 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Network Comparison Type	Hugo	Interaction Map	red	green	network_comparison
26s protease regulatory subunit 4 (p26s4). [swissprot;acc:q03527]	2962	Divided	PSMC1	Low confidence	200.017	196.692	1.0169
	2968	Subtracted					3.325
26s protease regulatory subunit 6a (tat-binding protein 1) (tbp-1) (proteasome subunit p50). [swissprot;acc:p17980]	2466		PSMC3	High confidence	216.64	217.285	0.645
	2474	Divided					1.00298
	2595			Low confidence	200.484	196.948	1.01795
	2596	Subtracted					3.536
26s protease regulatory subunit 6b (mip224) (mb67 interacting protein) (tat-binding protein-7) (tbp-7). [swissprot;acc:p43686]	1991	Divided	PSMC4		199.582	195.763	1.01951
	2044	Subtracted					3.819
	2323			High confidence	217.413	218.426	1.013
	2327	Divided					1.00466
26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998]	2321		PSMC2	Low confidence	198.366	194.732	1.01866
	2394	Subtracted		High confidence	218.192	219.014	0.822
	2395	Divided					1.00377
	2407	Subtracted		Low confidence	198.366	194.732	3.634
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210]	1637	Divided	PSMC5	High confidence	202.358	199.408	1.01479
	1682	Subtracted					2.95
	2149			Low confidence	200.982	197.22	3.762
	2163	Divided					1.01908
26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524]	2478		PSMC6	High confidence	216.177	216.801	1.00289
	2486	Subtracted					0.624
	3515	Divided		Low confidence	200.312	197.374	1.01489
	3521	Subtracted					2.938
26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [swissprot;acc:q99460]	830		PSMD1		204.36	199.229	5.131
	857	Divided					1.02575
	2355	Subtracted		High confidence	218.555	219.434	0.879
	2368	Divided					1.00402
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	2256	Subtracted	PSMD10		217.419	218.627	1.208
	2269	Divided					1.00556
	3038			Low confidence	200.303	197.031	1.01661
	3047	Subtracted					3.272
26s proteasome non-atpase regulatory subunit 11 (26s proteasome regulatory subunit s9) (26s proteasome regulatory subunit p44.5). [swissprot;acc:o00231]	2174	Divided	PSMD11		197.69	193.995	1.01905
	2274	Subtracted					3.695
	2353			High confidence	217.589	218.475	0.886
	2367	Divided					1.00407
26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232]	2300	Subtracted	no value		217.241	218.311	1.07
	2316	Divided					1.00493
	3393			Low confidence	198.522	195.526	1.01532
	3428	Subtracted					2.996
26s proteasome non-atpase regulatory subunit 13 (26s proteasome regulatory subunit s11) (26s proteasome regulatory subunit p40.5). [swissprot;acc:q9unm6]	2324		PSMD13	High confidence	217.112	218.116	1.004
	2329	Divided					1.00462
	2798			Low confidence	200.64	197.228	1.0173
	2828	Subtracted					3.412
26s proteasome non-atpase regulatory subunit 2 (26s proteasome regulatory subunit s2) (26s proteasome subunit p97) (tumor necrosis factor type 1 receptor associated protein 2) (55.11 protein). [swissprot;acc:q13200]	1918	Divided	PSMD2		199.382	195.527	1.01972
	1975	Subtracted					3.855
	2169			High confidence	210.209	208.808	1.401
	2175	Divided					1.00671
26s proteasome non-atpase regulatory subunit 3 (26s proteasome regulatory subunit s3) (proteasome subunit p58). [swissprot;acc:o43242]	2423	Subtracted	PSMD3		217.645	218.376	0.731
	2440	Divided					1.00336
	2613			Low confidence	200.463	196.947	1.01785
	2615	Subtracted					3.516

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.