MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 600 to 649 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	description	Network Comparison Type	red	green	network_comparison
300	probable atp-dependent 61 kda nucleolar rna helicase (dead-box protein 21). [swissprot;acc:q9ny93]	Subtracted	257.017	234.945	22.072
301	beta-1,4 mannosyltransferase. [refseq;acc:nm_019109]	Divided	150.982	166.372	1.10193
	melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801]	Subtracted	88.2482	110.265	22.0168
302	60s ribosomal protein l26. [swissprot;acc:q02877]	Divided	242.326	267.008	1.10185
	hepatocellular carcinoma-associated protein hca3. [refseq;acc:nm_138703]	Subtracted	88.2482	110.265	22.0168
303	60s ribosomal protein l35. [swissprot;acc:p42766]	Divided	242.333	266.999	1.10179
	melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]	Subtracted	88.2482	110.265	22.0168
304	40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]	Divided	242.339	266.986	1.1017
	melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]	Subtracted	88.2482	110.265	22.0168
305	melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]
	mitochondrial ribosomal protein l2. [refseq;acc:nm_015950]	Divided	242.339	266.986	1.1017
306	60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]		242.153	266.673	1.10126
	hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]	Subtracted	88.2482	110.265	22.0168
307	melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]
	serine racemase (ec 5.1.1.-). [swissprot;acc:q9gzt4]	Divided	242.153	266.673	1.10126
308	60s ribosomal protein l34. [swissprot;acc:p49207]
	necdin. [swissprot;acc:q99608]	Subtracted	88.2482	110.265	22.0168
309	melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]
	protein transport protein sec61 alpha subunit isoform 2 (sec61 alpha- 2). [swissprot;acc:q9y2r3]	Divided	242.153	266.673	1.10126
310	melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]	Subtracted	88.2482	110.265	22.0168
	protein transport protein sec61 alpha subunit isoform 1 (sec61 alpha- 1). [swissprot;acc:p38378]	Divided	242.153	266.673	1.10126
311	melanoma antigen, family b, 6. [refseq;acc:nm_173523]	Subtracted	88.2482	110.265	22.0168
	protein translation factor sui1 homolog gc20. [swissprot;acc:o60739]	Divided	242.627	267.151	1.10108
312	60s ribosomal protein l3-like. [swissprot;acc:q92901]		242.195	266.663	1.10103
	melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]	Subtracted	88.2482	110.265	22.0168
313	melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]
	ribonucleotide reductase m2 b (tp53 inducible); p53-inducible ribonucleotide reductase small subunit 2 homolog. [refseq;acc:nm_015713]	Divided	232.473	211.207	1.10069
314	melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]	Subtracted	88.2482	110.265	22.0168
	methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582]	Divided	244.126	268.604	1.10027
315	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]	Subtracted	88.2482	110.265	22.0168
	methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579]	Divided	244.126	268.604	1.10027
316	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]	Subtracted	88.2482	110.265	22.0168
	protein translation factor sui1 homolog (sui1iso1). [swissprot;acc:p41567]	Divided	242.694	267.017	1.10022
317	melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]	Subtracted	88.2482	110.265	22.0168
	splicing factor 3b subunit 3 (spliceosome associated protein 130) (sap 130) (sf3b130) (pre-mrna splicing factor sf3b 130 kda subunit). [swissprot;acc:q15393]	Divided	224.445	204.044	1.09998
318	melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]	Subtracted	88.2482	110.265	22.0168
	mitochondrial 60s ribosomal protein l3 (l3mt). [swissprot;acc:p09001]	Divided	242.011	266.18	1.09987
319	60s ribosomal protein l19. [swissprot;acc:p14118]		240.73	264.729	1.09969
	melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]	Subtracted	88.2482	110.265	22.0168
320	epithelial-cadherin precursor (e-cadherin) (uvomorulin) (cadherin-1) (cam 120/80). [swissprot;acc:p12830]	Divided	241.892	265.96	1.0995
	melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1]	Subtracted	88.2482	110.265	22.0168
321	c367g8.3 (novel protein similar to rpl23a (60s ribosomal protein l23a)) (60s ribosomal protein l23a like). [sptrembl;acc:q9br02]	Divided	241.892	265.959	1.09949
	trophinin. [swissprot;acc:q12816]	Subtracted	88.2482	110.265	22.0168
322	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]	Divided	86.7483	78.8995	1.09948
	ribonucleoside-diphosphate reductase m2 chain (ec 1.17.4.1) (ribonucleotide reductase small chain). [swissprot;acc:p31350]	Subtracted	231.969	210.064	21.905
323	40s ribosomal protein s14 (pro2640). [swissprot;acc:p06366]		242.238	264.11	21.872
	60s ribosomal protein l23a. [swissprot;acc:p29316]	Divided	241.884	265.945	1.09947
324	40s ribosomal protein s18 (ke-3) (ke3). [swissprot;acc:p25232]	Subtracted	242.238	264.11	21.872
	40s ribosomal protein s23. [swissprot;acc:p39028]	Divided	243.944	268.195	1.09941
325	28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.