MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1900 to 1949 of 3730 in total

Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence

description	Rank	Filtered	red	green	network_comparison
melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]	163	1	23693.7	18263	1.29736
	358	0	48	51	1.0625
melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]	158	1	23693.7	18263	1.29736
	355	0	48	51	1.0625
melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]	165	1	23693.7	18263	1.29736
	360	0	48	51	1.0625
melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]	164	1	23693.7	18263	1.29736
	359	0	48	51	1.0625
melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]	170	1	23693.7	18263	1.29736
	365	0	48	51	1.0625
melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]	166	1	23693.7	18263	1.29736
	361	0	48	51	1.0625
melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]	160	1	23693.7	18263	1.29736
	356	0	48	51	1.0625
melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1]	171	1	23693.7	18263	1.29736
	366	0	48	51	1.0625
melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]	161	1	23693.7	18263	1.29736
	357	0	48	51	1.0625
membrane protein expressed in epithelial-like lung adenocarcinoma. [refseq;acc:nm_024792]	1031	1	6136.99	6714.98	1.09418
membrane-associated nucleic acid binding protein. [refseq;acc:nm_018835]	2292		5783.76	6048.94	1.04585
membrane-associated transporter protein (aim-1 protein) (melanoma antigen aim1). [swissprot;acc:q9umx9]	453		3760.8	4315.06	1.14738
membrane-bound transcription factor site 2 protease (ec 3.4.24.-) (site-2 protease) (sterol-regulatory element-binding proteins intramembrane protease). [swissprot;acc:o43462]	3215		0.00001	0.00001	1
mesoderm induction early response 1. [refseq;acc:nm_020948]	294	0	1914.5	1723.5	1.11082
	1404	1	6291.89	6781.6	1.07783
metabotropic glutamate receptor 2 precursor (mglur2). [swissprot;acc:q14416]	1070		5494.73	6001.08	1.09215
metabotropic glutamate receptor 3 precursor (mglur3). [swissprot;acc:q14832]	90	0	34.6667	54.6667	1.57692
	1071	1	5494.73	6001.08	1.09215
metalloprotease 1; metalloprotease 1 (pitrilysin family). [refseq;acc:nm_014889]	142		9276.47	7090.37	1.30832
metastasis-associated protein mta1. [swissprot;acc:q13330]	467		4864.25	5573.62	1.14583
metaxin 1. [swissprot;acc:q13505]	150	0	933.395	723.368	1.29035
	685	1	9327.58	10442.2	1.1195
metaxin 2. [swissprot;acc:o75431]	1708		7033.72	7516.77	1.06868
methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582]	2099		3544.03	3359.43	1.05495
methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579]	2100
methionyl-trna formyltransferase, mitochondrial precursor (ec 2.1.2.9) (mtfmt). [swissprot;acc:q96dp5]	996		5110.6	5596.73	1.09512
methionyl-trna synthetase (ec 6.1.1.10) (methionine--trna ligase) (metrs). [swissprot;acc:p56192]	653		5560.06	6248.27	1.12378
methylenetetrahydrofolate reductase (ec 1.5.1.20). [swissprot;acc:p42898]	1680		6436.73	6882.16	1.0692
methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor (ec 1.2.1.27) (mmsdh). [swissprot;acc:q02252]	1135		5790.67	6303.95	1.08864
methyltransferase like 2. [refseq;acc:nm_018396]	118	0	31	43	1.3871
	731	1	13241.4	11864	1.1161
mevalonate kinase (ec 2.7.1.36) (mk). [swissprot;acc:q03426]	446	0	1549.26	1522.06	1.01787
	2507	1	4243.44	4352.56	1.02571
microfibril-associated glycoprotein 4 precursor. [swissprot;acc:p55083]	19		677.5	1865.5	2.75351
microfibrillar-associated protein 1. [swissprot;acc:p55081]	2949		0.00001	0.00001	1
microsomal signal peptidase 18 kda subunit (ec 3.4.-.-) (spase 18 kda subunit) (spc18) (endopeptidase sp18). [swissprot;acc:p21378]	358		5061.11	5950.22	1.17567
	390	0	11512.3	12011.7	1.04338
microsomal signal peptidase 25 kda subunit (ec 3.4.-.-) (spase 25 kda subunit) (spc25). [swissprot;acc:q15005]	2335	1	5123.89	5350.78	1.04428
microtubule-actin crosslinking factor 1, isoform 4. [swissprot;acc:q96pk2]	2663		4608.54	4576.35	1.00703
microtubule-associated protein 4 (map 4). [swissprot;acc:p27816]	2643		5935.71	5876.22	1.01012
microtubule-associated protein rp/eb family member 1 (apc-binding protein eb1). [swissprot;acc:q15691]	1744		6298.81	6722.65	1.06729

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.