MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Filtered	Value Type	green	network_comparison	Rank	Gene	Interaction Map	description	red	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Filtered  : 0
Value Type  : Measured

green	network_comparison	Rank	Interaction Map	description	red	Network Comparison Type
322.947	1.26947	148	Low confidence	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]	409.972	Divided
	87.025	469				Subtracted
323.433	1.26852	150		williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]	410.28	Divided
	86.847	470				Subtracted
323.685	1.26808	151		williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]	410.457	Divided
	86.772	471				Subtracted
327.517	1.92644	55	High confidence	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]	630.942	Divided
	303.425	103				Subtracted
330.189	1.93484	54		formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	638.862	Divided
	308.673	101				Subtracted
335	1.32937	133		bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]	252	Divided
	83	314				Subtracted
336.584	1.28908	143	Low confidence	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	261.105	Divided
		157	High confidence
	75.479	319				Subtracted
		497	Low confidence
339.154	1.19069	207	High confidence	cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]	403.827	Divided
	64.673	331				Subtracted
339.779	1.06422	485	Low confidence	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]	361.601	Divided
	21.822	733				Subtracted
346.751	1.32862	134	High confidence	mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362]	260.986	Divided
	85.765	309				Subtracted
351.772	1.76802	68		protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981]	198.964	Divided
	152.808	209				Subtracted
352.75	1.75762	71		ubiquitin protein ligase. [refseq;acc:nm_130466]	620	Divided
	267.25	119				Subtracted
354.349	1.16138	318	Low confidence	poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366]	305.111	Divided
	49.238	599				Subtracted
359.631	1.37479	120	High confidence	signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556]	494.417	Divided
	134.786	238				Subtracted
359.98	1.04852	382		guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	377.445	Divided
	17.465	433				Subtracted
362.023	1.04825	383		guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	379.489	Divided
	17.466	432				Subtracted
362.955	1.47569	101	Low confidence	60s ribosomal protein l37a. [swissprot;acc:p12751]	535.61	Divided
	172.655	301				Subtracted
363	1.19408	203	High confidence	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]	304	Divided
		296	Low confidence
	59	343	High confidence			Subtracted
		555	Low confidence
368.317	1.14829	229	High confidence	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]	320.752	Divided
	47.565	370				Subtracted
369.011	1.14972	227		transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]	424.258	Divided
	55.247	349				Subtracted
372.961	1.29544	145		likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033]	287.903	Divided
	85.058	312				Subtracted
375.343	1.21433	179	Low confidence	alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]	455.789	Divided
	80.446	481				Subtracted
377.574	1.29466	146	High confidence	cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2]	291.639	Divided
	85.935	308				Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.