MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Filtered	Value Type	green	Gene	Network Comparison Type	red	network_comparison	Interaction Map	Rank	description

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Filtered  : 0
Value Type  : Measured

green	Network Comparison Type	red	network_comparison	Interaction Map	Rank	description
322.947	Divided	409.972	1.26947	Low confidence	148	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]
	Subtracted		87.025		469
323.433	Divided	410.28	1.26852		150	williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]
	Subtracted		86.847		470
323.685	Divided	410.457	1.26808		151	williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]
	Subtracted		86.772		471
327.517	Divided	630.942	1.92644	High confidence	55	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]
	Subtracted		303.425		103
330.189	Divided	638.862	1.93484		54	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]
	Subtracted		308.673		101
335	Divided	252	1.32937		133	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]
	Subtracted		83		314
336.584	Divided	261.105	1.28908		157	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]
				Low confidence	143
	Subtracted		75.479	High confidence	319
				Low confidence	497
339.154	Divided	403.827	1.19069	High confidence	207	cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747]
	Subtracted		64.673		331
339.779	Divided	361.601	1.06422	Low confidence	485	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]
	Subtracted		21.822		733
346.751	Divided	260.986	1.32862	High confidence	134	mms19-like (met18 homolog, s. cerevisiae); homolog of yeast mms19; mms19 (met18 s. cerevisiae)-like. [refseq;acc:nm_022362]
	Subtracted		85.765		309
351.772	Divided	198.964	1.76802		68	protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [refseq;acc:nm_003981]
	Subtracted		152.808		209
352.75	Divided	620	1.75762		71	ubiquitin protein ligase. [refseq;acc:nm_130466]
	Subtracted		267.25		119
354.349	Divided	305.111	1.16138	Low confidence	318	poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366]
	Subtracted		49.238		599
359.631	Divided	494.417	1.37479	High confidence	120	signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556]
	Subtracted		134.786		238
359.98	Divided	377.445	1.04852		382	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]
	Subtracted		17.465		433
362.023	Divided	379.489	1.04825		383	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]
	Subtracted		17.466		432
362.955	Divided	535.61	1.47569	Low confidence	101	60s ribosomal protein l37a. [swissprot;acc:p12751]
	Subtracted		172.655		301
363	Divided	304	1.19408	High confidence	203	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]
				Low confidence	296
	Subtracted		59	High confidence	343
				Low confidence	555
368.317	Divided	320.752	1.14829	High confidence	229	dj718p11.1.2 (novel class ii aminotransferase similar to serine palmotyltransferase (isoform 2)) (fragment). [sptrembl;acc:q9ugb5]
	Subtracted		47.565		370
369.011	Divided	424.258	1.14972		227	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]
	Subtracted		55.247		349
372.961	Divided	287.903	1.29544		145	likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033]
	Subtracted		85.058		312
375.343	Divided	455.789	1.21433	Low confidence	179	alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]
	Subtracted		80.446		481
377.574	Divided	291.639	1.29466	High confidence	146	cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2]
	Subtracted		85.935		308

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.