MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	Rank	description	green	Value Type	Network Comparison Type	Interaction Map	Filtered	red	network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 1892 in total

green  : 0
Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0

Rank	description	Value Type
2768	histone h2a.x (h2a/x). [swissprot;acc:p16104]	Squared
		Rooted
2769	histone h2a.q (h2a/q) (h2a-gl101) (fragment). [swissprot;acc:q16777]	Measured
		Ranked
		Squared
		Rooted
2770	nipsnap1 protein. [swissprot;acc:q9bpw8]	Measured
		Ranked
		Squared
		Rooted
2771	t-box transcription factor tbx1 (t-box protein 1) (testis-specific t-box protein). [swissprot;acc:o43435]	Measured
		Ranked
		Squared
		Rooted
2772	uridine diphosphate glucose pyrophosphatase. [refseq;acc:nm_177533]	Measured
		Ranked
		Squared
		Rooted
2773	bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [swissprot;acc:p34820]	Measured
		Ranked
		Squared
		Rooted
2774	dc12 protein. [refseq;acc:nm_020187]	Measured
		Ranked
		Squared
		Rooted
2775	jerky protein homolog like (hhmjg). [swissprot;acc:q9y4a0]	Measured
		Ranked
		Squared
		Rooted
2776	bcl-6 interacting corepressor isoform 1. [refseq;acc:nm_017745]	Measured
		Ranked
		Squared
		Rooted
2777	guanine nucleotide exchange factor mss4 (rab interacting factor). [swissprot;acc:p47224]	Measured
		Ranked
		Squared
		Rooted
2778	transcription factor mammalian mafa (pancreatic beta-cell specific transcriptional activator). [sptrembl;acc:q8nhw3]	Measured
		Ranked
		Squared
		Rooted
2779	caveolin-3 (m-caveolin). [swissprot;acc:p56539]	Measured
		Ranked
		Squared
		Rooted
2780	importin alpha-2 subunit (karyopherin alpha-2 subunit) (srp1-alpha) (rag cohort protein 1). [swissprot;acc:p52292]	Measured
		Ranked
		Squared
		Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.