MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	Rank	description	Value Type	Network Comparison Type	Filtered	Interaction Map	green	red	network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 6456 in total

Value Type  : Measured
Filtered  : 1
Interaction Map  : High confidence

Rank	description	Network Comparison Type	green	red	network_comparison
26	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-12 subunit. [swissprot;acc:q9ubi6]	Divided	892.67	1833.01	2.0534
	hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]	Subtracted	18263	23693.7	5430.7
27	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	Divided	895.134	1834.33	2.04922
	melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]	Subtracted	18263	23693.7	5430.7
28	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-3 subunit. [swissprot;acc:p29798]	Divided	895.194	1834.36	2.04912
	necdin. [swissprot;acc:q99608]	Subtracted	18263	23693.7	5430.7
29	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-8 subunit (gamma-9). [swissprot;acc:q9uk08]	Divided	895.507	1834.52	2.04858
	melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]	Subtracted	18263	23693.7	5430.7
30	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 subunit. [swissprot;acc:p30670]	Divided	895.633	1834.59	2.04837
	melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]	Subtracted	18263	23693.7	5430.7
31	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-10 subunit. [swissprot;acc:p50151]	Divided	895.697	1834.63	2.04827
	melanoma antigen, family b, 6. [refseq;acc:nm_173523]	Subtracted	18263	23693.7	5430.7
32	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]	Divided	895.893	1834.73	2.04793
	melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]	Subtracted	18263	23693.7	5430.7
33	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-11 subunit. [swissprot;acc:p50152]	Divided	896.972	1835.3	2.04611
	melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]	Subtracted	18263	23693.7	5430.7
34	guanine nucleotide-binding protein g(y), alpha subunit (alpha-11). [swissprot;acc:p29992]	Divided	907.546	1836.71	2.02382
	melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]	Subtracted	18263	23693.7	5430.7
35	guanine nucleotide-binding protein g(q), alpha subunit. [swissprot;acc:p50148]	Divided	907.564	1836.71	2.02378
	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]	Subtracted	18263	23693.7	5430.7
36	guanine nucleotide-binding protein g(z), alpha subunit (g(x) alpha chain) (gz-alpha). [swissprot;acc:p19086]	Divided	907.741	1836.76	2.02344
	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]	Subtracted	18263	23693.7	5430.7
37	guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [swissprot;acc:p11488]	Divided	907.763	1836.76	2.02339
	melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]	Subtracted	18263	23693.7	5430.7
38	guanine nucleotide-binding protein g(t), alpha-2 subunit (transducin alpha-2 chain). [swissprot;acc:p19087]	Divided	907.774	1836.76	2.02337
	melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]	Subtracted	18263	23693.7	5430.7
39	guanine nucleotide-binding protein g(i), alpha-2 subunit (adenylate cyclase-inhibiting g alpha protein). [swissprot;acc:p04899]	Divided	907.903	1836.8	2.02312
	melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]	Subtracted	18263	23693.7	5430.7
40	guanine nucleotide-binding protein g(i), alpha-1 subunit (adenylate cyclase-inhibiting g alpha protein). [swissprot;acc:p04898]	Divided	907.978	1836.81	2.02297
	melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1]	Subtracted	18263	23693.7	5430.7
41	guanine nucleotide-binding protein g(k), alpha subunit (g(i) alpha-3). [swissprot;acc:p08754]	Divided	907.978	1836.81	2.02297
	trophinin. [swissprot;acc:q12816]	Subtracted	18263	23693.7	5430.7
42	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]		16426.1	21785.2	5359.1
	guanine nucleotide-binding protein beta subunit 5 (transducin beta chain 5). [swissprot;acc:o14775]	Divided	958.237	1857.32	1.93827
43	apg3p; pc3-96 protein. [refseq;acc:nm_022488]	Subtracted	16426.1	21785.2	5359.1
	guanine nucleotide-binding protein g(i)/g(s)/g(t) beta subunit 3 (transducin beta chain 3). [swissprot;acc:p16520]	Divided	1027.36	1881.02	1.83093
44	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]	Subtracted	33457.6	28136.5	5321.1
	guanine nucleotide-binding protein g(i)/g(s)/g(t) beta subunit 1 (transducin beta chain 1). [swissprot;acc:p04901]	Divided	1057.39	1931.34	1.82652
45	guanine nucleotide-binding protein beta subunit 4 (transducin beta chain 4). [swissprot;acc:q9hav0]		1056.02	1926.69	1.82448
	protein phosphatase 1, regulatory subunit 7; sds22. [refseq;acc:nm_002712]	Subtracted	22440.4	27642.5	5202.1
46	cleavage and polyadenylation specific factor 4, 30kd subunit; cleavage-polyadenylation specificity factor, 30kd; no arches-like (zebrafish) zinc finger protein; cleavage-polyadenylation specificity factor. [refseq;acc:nm_006693]		20431.7	24896.4	4464.7
	neurogenic differentiation factor 2 (neurod2). [swissprot;acc:q15784]	Divided	1390.33	779.167	1.78438
47	chromodomain helicase-dna-binding protein 3 (chd-3) (mi-2 autoantigen 240 kda protein) (mi2-alpha). [swissprot;acc:q12873]
	trs85 homolog. [swissprot;acc:q9y2l5]	Subtracted	20431.7	24896.4	4464.7
48	doc-1 related protein (doc-1r). [swissprot;acc:o75956]	Divided	1390.33	779.167	1.78438
	wd-repeat protein wdc146. [swissprot;acc:q9c0j8]	Subtracted	20369.9	24806.9	4437
49	cleavage and polyadenylation specificity factor, 160 kda subunit (cpsf 160 kda subunit). [swissprot;acc:q10570]
	neurogenic differentiation factor 6 (neurod6) (my051 protein). [swissprot;acc:q96nk8]	Divided	1390.33	779.167	1.78438
50	cleavage and polyadenylation specificity factor, 100 kda subunit (cpsf 100 kda subunit) (fragment). [swissprot;acc:q9p2i0]	Subtracted	20127.8	24473.9	4346.1
	neurogenic differentiation factor 1 (neurod1) (neurod). [swissprot;acc:q13562]	Divided	1390.33	779.167	1.78438

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.