MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 925 to 974 of 1948 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Value Type
2973	fructose-bisphosphate aldolase b (ec 4.1.2.13) (liver-type aldolase). [swissprot;acc:p05062]	Measured
		Ranked
		Squared
		Rooted
2974	cell division protein kinase 9 (ec 2.7.1.-) (serine/threonine-protein kinase pitalre) (c-2k). [swissprot;acc:p50750]	Measured
		Ranked
		Squared
		Rooted
2975	potassium channel tetramerisation domain containing 3; ny-ren-45 antigen. [refseq;acc:nm_016121]	Measured
		Ranked
		Squared
		Rooted
2976	mo25 protein (cgi-66). [swissprot;acc:q9y376]	Measured
		Ranked
		Squared
		Rooted
2977	cytochrome p450 27, mitochondrial precursor (ec 1.14.-.-) (cytochrome p-450c27/25) (sterol 26-hydroxylase) (sterol 27-hydroxylase) (vitamin d(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase). [swissprot;acc:q02318]	Measured
		Ranked
		Squared
		Rooted
2978	integrin alpha-7 precursor. [swissprot;acc:q13683]	Measured
		Ranked
		Squared
		Rooted
2979	udp-glucuronosyltransferase 2b28 precursor, microsomal (ec 2.4.1.17). [swissprot;acc:q9by64]	Measured
		Ranked
		Squared
		Rooted
2980	ste20-like kinase; ste2-like kinase. [refseq;acc:nm_016281]	Measured
		Ranked
		Squared
		Rooted
2981	zinc finger daz interacting protein 1. [refseq;acc:nm_014934]	Measured
		Ranked
		Squared
		Rooted
2982	serine/threonine protein kinase mask; ste20-like kinase mst4. [refseq;acc:nm_016542]	Measured
		Ranked
		Squared
		Rooted
2983	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]	Measured
		Ranked
		Squared
		Rooted
2984	similar to cg5057 gene product. [sptrembl;acc:q9btt4]	Measured
		Ranked
		Squared
		Rooted
2985	myosin heavy chain, smooth muscle isoform (smmhc). [swissprot;acc:p35749]	Measured
		Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.