MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 151 to 200 of 8289 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1

Rank	description	Interaction Map	red	green	network_comparison
76	db83 protein. [swissprot;acc:p57088]	High confidence	288	362	1.25694
	nipsnap1 protein. [swissprot;acc:q9bpw8]	Low confidence	249.584	226.86	1.10017
77	putative adenosylhomocysteinase 3 (ec 3.3.1.1) (s-adenosyl-l- homocysteine hydrolase) (adohcyase). [swissprot;acc:q96hn2]		195.851	215.424	1.09994
	voltage-dependent calcium channel gamma-2 subunit (neuronal voltage- gated calcium channel gamma-2 subunit). [swissprot;acc:q9y698]	High confidence	254.692	202.668	1.2567
78	malignant cell expression-enhanced gene/tumor progression-enhanc. [refseq;acc:nm_024298]	Low confidence	211	231.635	1.0978
	voltage-dependent calcium channel gamma-8 subunit (neuronal voltage- gated calcium channel gamma-8 subunit). [swissprot;acc:q8wxs5]	High confidence	254.693	202.668	1.2567
79	amyloid beta a4 precursor protein-binding family a member 1 (neuron- specific x11 protein) (neuronal munc18-1-interacting protein 1) (mint-1) (adapter protein x11alpha). [swissprot;acc:q02410]	Low confidence	229.144	208.803	1.09742
	voltage-dependent calcium channel gamma-3 subunit (neuronal voltage- gated calcium channel gamma-3 subunit). [swissprot;acc:o60359]	High confidence	254.693	202.668	1.2567
80	rad50-interacting protein 1. [refseq;acc:nm_021930]	Low confidence	221.194	202.005	1.09499
	voltage-dependent calcium channel gamma-4 subunit (neuronal voltage- gated calcium channel gamma-4 subunit). [swissprot;acc:q9ubn1]	High confidence	254.691	202.668	1.25669
81	transcription factor dp-2 (e2f dimerization partner 2). [swissprot;acc:q14188]	Low confidence	227.623	208.281	1.09286
	voltage-dependent calcium channel gamma-5 subunit (neuronal voltage- gated calcium channel gamma-5 subunit). [swissprot;acc:q9uf02]	High confidence	254.614	202.646	1.25645
82	diacylglycerol kinase, eta isoform 1. [refseq;acc:nm_152910]	Low confidence	226.981	208.077	1.09085
	guanine nucleotide-binding protein beta subunit 5 (transducin beta chain 5). [swissprot;acc:o14775]	High confidence	267.636	335.359	1.25304
83	diacylglycerol kinase, delta (ec 2.7.1.107) (diglyceride kinase) (dgk-delta) (dag kinase delta) (130 kda diacylglycerol kinase) (fragment). [swissprot;acc:q16760]	Low confidence	226.981	208.077	1.09085
	melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801]	High confidence	88.2482	110.265	1.24949
84	hepatocellular carcinoma-associated protein hca3. [refseq;acc:nm_138703]
	transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186]	Low confidence	226.338	207.874	1.08882
85	melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]	High confidence	88.2482	110.265	1.24949
	potassium voltage-gated channel, shal-related subfamily, member 2; voltage-sensitive potassium channel; voltage-gated potassium channel kv4.2. [refseq;acc:nm_012281]	Low confidence	225.735	245.308	1.08671
86	dna fragmentation factor 40 kda subunit (ec 3.-.-.-) (dff-40) (caspase-activated deoxyribonuclease) (caspase-activated dnase) (cad) (caspase-activated nuclease) (cpan). [swissprot;acc:o76075]		233.922	215.309	1.08645
	melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]	High confidence	88.2482	110.265	1.24949
87	melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]
	potassium voltage-gated channel, shal-related subfamily, member 3 isoform 1; sha1-related potassium channel kv4.3; voltage-gated k+ channel; potassium ionic channel kv4.3; voltage-gated potassium channel kv4.3. [refseq;acc:nm_004980]	Low confidence	225.545	244.933	1.08596
88	hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]	High confidence	88.2482	110.265	1.24949
	potassium voltage-gated channel, shal-related subfamily, member 1; shal-type potassium channel; voltage-gated potassium channel kv4.1. [refseq;acc:nm_004979]	Low confidence	225.428	244.701	1.0855
89	melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]	High confidence	88.2482	110.265	1.24949
	star-related lipid transfer protein 7 (stard7) (start domain- containing protein 7) (gtt1 protein). [swissprot;acc:q9nqz5]	Low confidence	228.743	210.764	1.0853
90	necdin. [swissprot;acc:q99608]	High confidence	88.2482	110.265	1.24949
	tbp-associated factor 2; taf2 rna polymerase ii, tata box binding protein (tbp)-associated factor, 150 kd; tata box binding protein (tbp)-associated factor, rna polymerase ii, b, 150kd; cofactor of initiator function, 150kd subunit. [refseq;acc:nm_003184]	Low confidence	237.567	219.229	1.08365
91	melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]	High confidence	88.2482	110.265	1.24949
	oligophrenin 1. [swissprot;acc:o60890]	Low confidence	233.837	215.973	1.08271
92	melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]	High confidence	88.2482	110.265	1.24949
	oligophrenin-1 like protein (gtpase regulator associated with focal adhesion kinase). [swissprot;acc:q9una1]	Low confidence	233.592	215.846	1.08222
93	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552]		247.334	228.84	1.08082
	melanoma antigen, family b, 6. [refseq;acc:nm_173523]	High confidence	88.2482	110.265	1.24949
94	melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]
	ras gtpase-activating protein ngap (ras protein activator like 1). [swissprot;acc:q9ujf2]	Low confidence	247.087	228.693	1.08043
95	amino acid transporter xat2; likely ortholog of mouse aspartate/glutamate transporter 1 (agt1). [refseq;acc:nm_138817]		200.497	185.679	1.0798
	melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]	High confidence	88.2482	110.265	1.24949
96	melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]
	y+l amino acid transporter 1 (y(+)l-type amino acid transporter 1) (y+lat-1) (y+lat1) (monocyte amino acid permease 2) (mop-2). [swissprot;acc:q9um01]	Low confidence	200.497	185.679	1.0798
97	cystine/glutamate transporter (amino acid transport system xc-) (xct) (calcium channel blocker resistance protein ccbr1). [swissprot;acc:q9upy5]
	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]	High confidence	88.2482	110.265	1.24949
98	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]
	solute carrier family 7 (cationic amino acid transporter, y+ system), member 6. [refseq;acc:nm_003983]	Low confidence	200.497	185.679	1.0798
99	eukaryotic translation initiation factor 4b (eif-4b). [swissprot;acc:p23588]
	melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]	High confidence	88.2482	110.265	1.24949
100	b(0,+)-type amino acid transporter 1 (b(0,+)at) (glycoprotein- associated amino acid transporter b0,+at1). [swissprot;acc:p82251]	Low confidence	200.497	185.679	1.0798
	melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]	High confidence	88.2482	110.265	1.24949

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.