MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	Rank	description	Value Type	Network Comparison Type	Filtered	Interaction Map	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1001 to 1050 of 9634 in total

Value Type  : Ranked
Network Comparison Type  : Divided

Rank	description	Filtered	Interaction Map	red	green	network_comparison
251	keratin associated protein 4-10; keratin associated protein 4.10. [refseq;acc:nm_033060]	0	High confidence	10551.6	11573.6	1.09686
	nadph oxidase, ef hand calcium-binding domain 5. [refseq;acc:nm_024505]	1	Low confidence	210.415	201.035	1.04666
	oligopeptide transporter, small intestine isoform (peptide transporter 1) (intestinal h+/peptide cotransporter) (solute carrier family 15, member 1). [swissprot;acc:p46059]		High confidence	186.172	166.661	1.11707
	zinc finger protein 93 (zinc finger protein htf34) (fragment). [swissprot;acc:p35789]	0	Low confidence	4257.49	4854.46	1.14022
252	cytochrome b-245 heavy chain (p22 phagocyte b-cytochrome) (neutrophil cytochrome b, 91 kda polypeptide) (cgd91-phox) (gp91-phox) (heme binding membrane glycoprotein gp91phox) (cytochrome b(558) beta chain) (superoxide-generating nadph oxidase heavy chain subunit). [swissprot;acc:p04839]	1		210.414	201.035	1.04665
	eukaryotic translation initiation factor 4 gamma (eif-4-gamma) (eif- 4g) (eif4g) (p220). [swissprot;acc:q04637]		High confidence	237.292	212.457	1.11689
	keratin associated protein 4-14; keratin associated protein 4.14. [refseq;acc:nm_033059]	0		10551.6	11573.5	1.09685
	zinc finger protein zfp. [refseq;acc:nm_018651]		Low confidence	4257.65	4854.63	1.14021
253	keratin associated protein 4.9 (fragment). [sptrembl;acc:q9byq8]		High confidence	10551.6	11573.5	1.09685
	krab zinc finger protein. [sptrembl;acc:q96jc4]		Low confidence	4257.65	4854.63	1.14021
	mad protein (max dimerizer). [swissprot;acc:q05195]	1	High confidence	228	204.333	1.11583
	nadph oxidase 4. [refseq;acc:nm_016931]		Low confidence	210.413	201.035	1.04665
254	keratin associated protein 4-12; keratin associated protein 4.12. [refseq;acc:nm_031854]	0	High confidence	10551.6	11573.5	1.09685
	nadph oxidase 3; nadph oxidase catalytic subunit-like 3. [refseq;acc:nm_015718]	1	Low confidence	210.414	201.035	1.04665
	source of immunodominant mhc-associated peptides; homolog of yeast stt3 gene. [refseq;acc:nm_178862]		High confidence	200.691	179.88	1.11569
	zinc finger protein loc163140 (fragment). [sptrembl;acc:q86wm6]	0	Low confidence	4257.81	4854.79	1.14021
255	nadph oxidase homolog 1 (nox-1) (noh-1) (nadh/nadph mitogenic oxidase subunit p65-mox) (mitogenic oxidase 1) (mox1). [swissprot;acc:q9y5s8]	1		210.413	201.035	1.04665
	oligosaccharyl transferase stt3 subunit homolog (b5) (integral membrane protein 1) (tmc). [swissprot;acc:p46977]		High confidence	200.691	179.88	1.11569
	star-related lipid transfer protein 6 (stard6) (start domain- containing protein 6). [swissprot;acc:p59095]	0		10551.6	11573.5	1.09685
	zinc finger protein 431. [swissprot;acc:q8tf32]		Low confidence	4258.04	4855.04	1.14021
256	espin. [refseq;acc:nm_031475]		High confidence	10551.6	11573.4	1.09684
	max interacting protein 1 (mxi1 protein). [swissprot;acc:p50539]	1		227.999	204.357	1.11569
	oligosaccharyl transferase stt3 subunit homolog (b5) (integral membrane protein 1) (tmc). [swissprot;acc:p46977]		Low confidence	199.376	190.521	1.04648
	zinc finger protein 267 (zinc finger protein hzf2). [swissprot;acc:q14586]	0		4258.04	4855.04	1.14021
257	dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit precursor (ec 2.4.1.119) (oligosaccharyl transferase 48 kda subunit) (ddost 48 kda subunit). [swissprot;acc:p39656]	1	High confidence	200.691	179.88	1.11569
	keratin associated protein 9-4; keratin associated protein 9.4. [refseq;acc:nm_033191]	0		10552.2	11566.4	1.09611
	tropomyosin alpha 3 chain (tropomyosin 3) (tropomyosin gamma). [swissprot;acc:p06753]	1	Low confidence	201.316	192.404	1.04632
	zinc finger protein 180 (hhz168). [swissprot;acc:q9ujw8]	0		4258.04	4855.04	1.14021
258	40s ribosomal protein s28. [swissprot;acc:p25112]		High confidence	12967.1	14193.6	1.09459
	max-interacting transcriptional repressor mad4 (max-associated protein 4) (max dimerization protein 4). [swissprot;acc:q14582]	1		227.999	204.366	1.11564
	tropomyosin 1 alpha chain (alpha-tropomyosin). [swissprot;acc:p09493]		Low confidence	201.304	192.427	1.04613
	zinc finger protein 28 homolog (zfp-28) (kruppel-like zinc finger factor x6). [swissprot;acc:q8nhy6]	0		4257.81	4854.79	1.14021
259	adenylyl cyclase-associated protein 2 (cap 2). [swissprot;acc:p40123]		High confidence	10438.3	9549.77	1.09304
	max dimerization protein 3; likely ortholog of mouse max dimerization protein 3. [refseq;acc:nm_031300]	1		227.999	204.37	1.11562
	trans-prenyltransferase; polyprenyl pyrophosphate synthetase. [refseq;acc:nm_014317]		Low confidence	211.794	202.482	1.04599
	zinc finger protein 79 (znfpt7) (fragment). [swissprot;acc:q15937]	0		4258.04	4855.04	1.14021
260	40s ribosomal protein s4, y isoform 2. [swissprot;acc:q8td47]		High confidence	12447.6	11392.6	1.0926
	ankyrin repeat domain protein 7 (testis-specific protein tsa806). [swissprot;acc:q92527]	1	Low confidence	216.855	207.34	1.04589
	c439a6.1 (novel protein similar to heparan sulfate (glucosamine) 3-o- sulfotransferases) (fragment). [sptrembl;acc:q96qi5]		High confidence	219.421	196.978	1.11394
	zinc finger protein 463; c2h2-like zinc finger protein. [refseq;acc:nm_018555]	0	Low confidence	4258.35	4855.37	1.1402
261	40s ribosomal protein s4, x isoform (single copy abundant mrna protein) (scr10). [swissprot;acc:p12750]		High confidence	12448.9	11393.9	1.09259
	ba526d8.2 (novel protein similar to kiaa1074). [sptrembl;acc:q9h560]	1	Low confidence	216.845	207.333	1.04588
	heparan sulfate d-glucosaminyl 3-o-sulfotransferase 3a1; heparin-glucosamine 3-o-sulfotransferase. [refseq;acc:nm_006042]		High confidence	219.421	196.978	1.11394
	zinc finger protein 126 (hzf-2) (fragment). [swissprot;acc:p35275]	0	Low confidence	4259.13	4856.2	1.14019
262	breast cancer antigen ny-br-1. [refseq;acc:nm_052997]	1		216.842	207.332	1.04587
	heparan sulfate d-glucosaminyl 3-o-sulfotransferase 3b1. [refseq;acc:nm_006041]		High confidence	219.421	196.978	1.11394
	sirtuin 7; sir2-related protein type 7; sirtuin type 7; sirtuin (silent mating type information regulation 2, s.cerevisiae, homolog) 7; silent mating type information regulation 2, s.cerevisiae, homolog 7; sirtuin silent mating type information regulation 2 homolog 7 (s. cerevisiae). [refseq;acc:nm_016538]	0		3464	3778	1.09065
	zinc finger protein 345 (zinc finger protein hzf10). [swissprot;acc:q14585]		Low confidence	4259.67	4856.77	1.14018
263	dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2]		High confidence	13573.3	14801.2	1.09046
	heparan sulfate d-glucosaminyl 3-o-sulfotransferase 2; heparin-glucosamine 3-o-sulfotransferase. [refseq;acc:nm_006043]	1		219.421	196.978	1.11394

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.