MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Gene	Rank	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 101 to 150 of 3730 in total

Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence

description	Rank	Filtered	red	green	network_comparison
40s ribosomal protein s5. [swissprot;acc:p46782]	2343	1	3672.17	3516.98	1.04413
40s ribosomal protein s7 (s8). [swissprot;acc:p23821]	1642		5782.92	6186.39	1.06977
40s ribosomal protein s8. [swissprot;acc:p09058]	1471		5659.45	6087.55	1.07564
40s ribosomal protein s9. [swissprot;acc:p46781]	2628		3933.74	3877.14	1.0146
40s ribosomal protein sa (p40) (34/67 kda laminin receptor) (colon carcinoma laminin-binding protein) (nem/1chd4) (multidrug resistance- associated protein mgr1-ag). [swissprot;acc:p08865]	315	0	1212.82	1104.61	1.09796
	2402	1	5078.5	5275.76	1.03884
43 kda receptor-associated protein of the synapse (rapsyn) (acetylcholine receptor-associated 43 kda protein) (43 kda postsynaptic protein). [swissprot;acc:q13702]	1402		6160.06	6640.78	1.07804
44050 protein. [refseq;acc:nm_178832]	376		17385.9	14889.2	1.16769
45 kda calcium-binding protein precursor (cab45) (stromal cell-derived factor 4) (sdf-4). [swissprot;acc:q9brk5]	972		7813.48	8570.11	1.09684
5'-amp-activated protein kinase, beta-1 subunit (ampk beta-1 chain) (ampkb). [swissprot;acc:q9y478]	691		6920.69	7747.63	1.11949
5'-amp-activated protein kinase, beta-2 subunit (ampk beta-2 chain). [swissprot;acc:o43741]	689
5'-amp-activated protein kinase, catalytic alpha-1 chain (ec 2.7.1.-) (ampk alpha-1 chain). [swissprot;acc:q13131]	688		6920.67	7747.6
5'-amp-activated protein kinase, catalytic alpha-2 chain (ec 2.7.1.-) (ampk alpha-2 chain). [swissprot;acc:p54646]	687		6920.71	7747.65
5'-amp-activated protein kinase, gamma-1 subunit (ampk gamma-1 chain) (ampkg). [swissprot;acc:p54619]	686		6920.69	7747.63
5'-amp-activated protein kinase, gamma-2 subunit (ampk gamma-2 chain) (ampk gamma2) (h91620p). [swissprot;acc:q9ugj0]	692
5'-amp-activated protein kinase, gamma-3 subunit (ampk gamma-3 chain) (ampk gamma3). [swissprot;acc:q9ugi9]	690
5'-methylthioadenosine phosphorylase (ec 2.4.2.28) (mta phosphorylase) (mtapase). [swissprot;acc:q13126]	1606		5232.99	5606.53	1.07138
5,6-dihydroxyindole-2-carboxylic acid oxidase precursor (ec 1.14.18.-) (dhica oxidase) (tyrosinase-related protein 1) (trp-1) (trp1) (trp) (catalase b) (glycoprotein-75) (melanoma antigen gp75). [swissprot;acc:p17643]	57	0	270.264	142.417	1.89769
	1229	1	5998.69	6509.74	1.08519
5-aminolevulinic acid synthase, erythroid-specific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-e). [swissprot;acc:p22557]	1910		6858.84	7287.27	1.06246
5-aminolevulinic acid synthase, nonspecific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-h). [swissprot;acc:p13196]	287	0	726.245	808.929	1.11385
	1915	1	6858.84	7287.27	1.06246
5-formyltetrahydrofolate cyclo-ligase (ec 6.3.3.2) (5,10-methenyl- tetrahydrofolate synthetase) (methenyl-thf synthetase) (mthfs). [swissprot;acc:p49914]	1833		6175.23	6572.85	1.06439
5-methyltetrahydrofolate--homocysteine methyltransferase (ec 2.1.1.13) (methionine synthase, vitamin-b12 dependent) (ms). [swissprot;acc:q99707]	1115		5795.13	6314.19	1.08957
54 kda nuclear rna- and dna-binding protein (p54(nrb)) (p54nrb) (55 kda nuclear protein) (nmt55) (non-pou domain-containing octamer- binding protein) (dna-binding p52/p100 complex, 52 kda subunit). [swissprot;acc:q15233]	2028		10243.4	9686.82	1.05746
6-phosphofructokinase, liver type (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme b) (pfk-b). [swissprot;acc:p17858]	764		4250.18	4729.12	1.11269
6-phosphofructokinase, muscle type (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme a) (pfk-a) (phosphofructokinase-m). [swissprot;acc:p08237]	763		4250.54	4729.67	1.11272
6-phosphofructokinase, type c (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme c) (pfk-c) (6-phosphofructokinase, platelet type). [swissprot;acc:q01813]	759		4254.62	4736.03	1.11315
6-phosphogluconate dehydrogenase, decarboxylating (ec 1.1.1.44). [swissprot;acc:p52209]	1339		5988.06	6464.94	1.07964
6-phosphogluconolactonase (ec 3.1.1.31) (6pgl). [swissprot;acc:o95336]	1627		6038.46	6463.9	1.07046
6-pyruvoyl tetrahydrobiopterin synthase (ec 4.2.3.12) (ptps) (ptp synthase). [swissprot;acc:q03393]	2904		0.00001	0.00001	1
60 kda heat shock protein, mitochondrial precursor (hsp60) (60 kda chaperonin) (cpn60) (heat shock protein 60) (hsp-60) (mitochondrial matrix protein p1) (p60 lymphocyte protein) (hucha60). [swissprot;acc:p10809]	1313		5457.14	5899.85	1.08112
60 kda tat interactive protein (tip60) (hiv-1 tat interactive protein) (cpla(2) interacting protein). [swissprot;acc:q92993]	1751		6011.57	6414.98	1.06711
60s acidic ribosomal protein p0 (l10e). [swissprot;acc:p05388]	2258		5150.31	5388.05	1.04616
60s acidic ribosomal protein p1. [swissprot;acc:p05386]	313	0	6131.07	6739.34	1.09921
	2418	1	4857.03	5039.78	1.03763
60s acidic ribosomal protein p2. [swissprot;acc:p05387]	2743		4824.49	4813.92	1.0022
60s ribosomal protein l10 (qm protein) (tumor suppressor qm) (laminin receptor homolog). [swissprot;acc:p27635]	269	0	1217.92	1367.83	1.12309
	2233	1	3614.08	3450.07	1.04754
60s ribosomal protein l10a (csa-19). [swissprot;acc:p53025]	322	0	1621.1	1771.04	1.09249
	2255	1	3624.59	3463.37	1.04655
60s ribosomal protein l11, mitochondrial precursor (l11mt) (cgi-113). [swissprot;acc:q9y3b7]	2417		3598.55	3467.65	1.03775
60s ribosomal protein l11. [swissprot;acc:p39026]	1834		3593.24	3375.93	1.06437
60s ribosomal protein l12 like protein. [sptrembl;acc:o60886]	330	0	1658.23	1805.52	1.08882
	2186	1	3586.3	3414.4	1.05035
60s ribosomal protein l12, mitochondrial precursor (l12mt) (5c5-2). [swissprot;acc:p52815]	2372		3677.53	3526.65	1.04278
60s ribosomal protein l12. [swissprot;acc:p30050]	328	0	1657.78	1805.05	1.08884
	2185	1	3586.32	3414.42	1.05035
60s ribosomal protein l13, mitochondrial (l13mt). [swissprot;acc:q9byd1]	2447		3730.53	3611.05	1.03309
60s ribosomal protein l13a (23 kda highly basic protein). [swissprot;acc:p40429]	2449		3730.74	3611.45	1.03303

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.