MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Gene	Rank	Value Type	description	Filtered	Network Comparison Type	Interaction Map	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 101 to 150 of 1948 in total

Filtered  : 1
Network Comparison Type  : Subtracted
Interaction Map  : High confidence
red  : 0
network_comparison  : 0
green  : 0

Rank	Value Type	description
2767	Measured	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]
	Ranked
	Squared
	Rooted
2768	Measured	histone h2a.x (h2a/x). [swissprot;acc:p16104]
	Ranked
	Squared
	Rooted
2769	Measured	histone h2a.q (h2a/q) (h2a-gl101) (fragment). [swissprot;acc:q16777]
	Ranked
	Squared
	Rooted
2770	Measured	nipsnap1 protein. [swissprot;acc:q9bpw8]
	Ranked
	Squared
	Rooted
2771	Measured	t-box transcription factor tbx1 (t-box protein 1) (testis-specific t-box protein). [swissprot;acc:o43435]
	Ranked
	Squared
	Rooted
2772	Measured	uridine diphosphate glucose pyrophosphatase. [refseq;acc:nm_177533]
	Ranked
	Squared
	Rooted
2773	Measured	bone morphogenetic protein 8 precursor (bmp-8) (osteogenic protein 2) (op-2). [swissprot;acc:p34820]
	Ranked
	Squared
	Rooted
2774	Measured	dc12 protein. [refseq;acc:nm_020187]
	Ranked
	Squared
	Rooted
2775	Measured	jerky protein homolog like (hhmjg). [swissprot;acc:q9y4a0]
	Ranked
	Squared
	Rooted
2776	Measured	bcl-6 interacting corepressor isoform 1. [refseq;acc:nm_017745]
	Ranked
	Squared
	Rooted
2777	Measured	guanine nucleotide exchange factor mss4 (rab interacting factor). [swissprot;acc:p47224]
	Ranked
	Squared
	Rooted
2778	Measured	transcription factor mammalian mafa (pancreatic beta-cell specific transcriptional activator). [sptrembl;acc:q8nhw3]
	Ranked
	Squared
	Rooted
2779	Measured	caveolin-3 (m-caveolin). [swissprot;acc:p56539]
	Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.