MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 651 to 700 of 8289 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1

Rank	description	Interaction Map	red	green	network_comparison
326	60s ribosomal protein l5. [swissprot;acc:p46777]	High confidence	241.899	265.924	1.09932
	dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kda subunit precursor (ec 2.4.1.119) (oligosaccharyl transferase 48 kda subunit) (ddost 48 kda subunit). [swissprot;acc:p39656]	Low confidence	199.343	191.59	1.04047
327	bet3 homolog. [swissprot;acc:o43617]		197.221	189.574	1.04034
	dna-directed rna polymerase ii largest subunit (ec 2.7.7.6) (rpb1). [swissprot;acc:p24928]	High confidence	243.817	267.962	1.09903
328	atp-dependent rna helicase ddx24 (dead-box protein 24). [swissprot;acc:q9gzr7]		258.437	235.183	1.09888
	splicing factor 3b subunit 2 (spliceosome associated protein 145) (sap 145) (sf3b150) (pre-mrna splicing factor sf3b 145 kda subunit). [swissprot;acc:q13435]	Low confidence	203.162	195.289	1.04031
329	exocyst complex component exo70. [swissprot;acc:q9upt5]		204.124	212.339	1.04025
	neurogenic differentiation factor 2 (neurod2). [swissprot;acc:q15784]	High confidence	312	284	1.09859
330	chromodomain helicase-dna-binding protein 3 (chd-3) (mi-2 autoantigen 240 kda protein) (mi2-alpha). [swissprot;acc:q12873]
	senescence marker protein-30 (smp-30) (regucalcin) (rc). [swissprot;acc:q15493]	Low confidence	221.437	212.889	1.04015
331	doc-1 related protein (doc-1r). [swissprot;acc:o75956]	High confidence	312	284	1.09859
	udp-glucose 4-epimerase (ec 5.1.3.2) (galactowaldenase) (udp- galactose 4-epimerase). [swissprot;acc:q14376]	Low confidence	200.249	192.535	1.04007
332	dynein intermediate chain 1, cytosolic (dh ic-1) (cytoplasmic dynein intermediate chain 1). [swissprot;acc:o14576]		209.495	201.474	1.03981
	neurogenic differentiation factor 6 (neurod6) (my051 protein). [swissprot;acc:q96nk8]	High confidence	312	284	1.09859
333	neurogenic differentiation factor 1 (neurod1) (neurod). [swissprot;acc:q13562]
	protein c20orf43 (hspc164/hspc169) (ad-007) (cda05). [swissprot;acc:q9by42]	Low confidence	200.482	208.446	1.03972
334	coiled-coil protein bicd2; homolog of drosophila bicaudal d. [refseq;acc:nm_015250]		202.616	194.878	1.03971
	neurogenic differentiation factor 4 (neurod4). [swissprot;acc:q9hd90]	High confidence	312	284	1.09859
335	bicaudal d homolog 1; bicaudal-d, drosophila, homolog of, 1. [refseq;acc:nm_001714]	Low confidence	202.616	194.878	1.03971
	chromodomain helicase dna binding protein 5. [refseq;acc:nm_015557]	High confidence	312	284	1.09859
336	cyclin-dependent kinase 2-associated protein 1 (cdk2-associated protein 1) (putative oral cancer suppressor) (deleted in oral cancer- 1) (doc-1). [swissprot;acc:o14519]
	tuftelin-interacting protein 11 (hspc006). [swissprot;acc:q9ubb9]	Low confidence	202.616	194.878	1.03971
337	60s ribosomal protein l12. [swissprot;acc:p30050]	High confidence	243.583	267.527	1.0983
	serine/threonine-protein kinase kkialre (ec 2.7.1.-) (cyclin-dependent kinase-like 1). [swissprot;acc:q00532]	Low confidence	201.873	194.181	1.03961
338	60s ribosomal protein l12 like protein. [sptrembl;acc:o60886]	High confidence	243.583	267.528	1.0983
	spliceosomal u5 snrnp-specific 15 kda protein (dim1 protein homolog) (thioredoxin-like u5 snrnp protein u5-15kd). [swissprot;acc:o14834]	Low confidence	202.572	194.86	1.03958
339	dj999l4.1 (novel protein similar to ribosomal protein l12 (rpl12)). [sptrembl;acc:q9nq02]	High confidence	243.583	267.527	1.0983
	geranylgeranyl pyrophosphate synthetase (ggpp synthetase) (ggppsase) (geranylgeranyl diphosphate synthase) [includes: dimethylallyltransferase (ec 2.5.1.1); geranyltranstransferase (ec 2.5.1.10); farnesyltranstransferase (ec 2.5.1.29)]. [swissprot;acc:o95749]	Low confidence	209.518	201.554	1.03951
340	blocked early in transport 1 homolog (s. cerevisiae) like; golgi snare 15 kda protein. [refseq;acc:nm_016526]		201.827	194.178	1.03939
	myelin gene expression factor 2. [refseq;acc:nm_016132]	High confidence	235.383	258.476	1.09811
341	60s ribosomal protein l9. [swissprot;acc:p32969]		240.243	263.798	1.09805
	kv channel interacting protein 1; vesicle apc-binding protein; a-type potassium channel modulatory protein 1. [refseq;acc:nm_014592]	Low confidence	214.027	222.415	1.03919
342	40s ribosomal protein s20. [swissprot;acc:p17075]	High confidence	243.5	267.21	1.09737
	tho complex 3. [refseq;acc:nm_032361]	Low confidence	186.383	179.374	1.03907
343	potassium channel-interacting protein 4 isoform 4; calsenilin-like protein. [refseq;acc:nm_147183]		213.982	222.326	1.03899
	protein arginine n-methyltransferase 3 (ec 2.1.1.-) (fragment). [swissprot;acc:o60678]	High confidence	241.625	265.136	1.0973
344	40s ribosomal protein s2 (s4) (llrep3 protein). [swissprot;acc:p15880]
	mitochondrial ribosomal protein l44. [refseq;acc:nm_022915]	Low confidence	216.283	208.173	1.03896
345	kv channel interacting protein 2 isoform 4; a-type potassium channel modulatory protein 2; cardiac voltage gated potassium channel modulatory subunit. [refseq;acc:nm_173193]		213.976	222.312
	ump-cmp kinase (ec 2.7.4.14) (cytidylate kinase) (deoxycytidylate kinase) (cytidine monophosphate kinase). [swissprot;acc:p30085]	High confidence	242.14	265.697	1.09729
346	40s ribosomal protein s3. [swissprot;acc:p23396]		241.612	265.119
	dynein intermediate chain 2, cytosolic (dh ic-2) (cytoplasmic dynein intermediate chain 2). [swissprot;acc:q13409]	Low confidence	209.221	201.38	1.03894
347	gtp:amp phosphotransferase mitochondrial (ec 2.7.4.10) (ak3) (adenylate kinase 3 alpha like 1). [swissprot;acc:q9uij7]	High confidence	242.14	265.697	1.09729
	nucleoside diphosphate kinase 7 (ec 2.7.4.6) (ndk 7) (ndp kinase 7) (nm23-h7). [swissprot;acc:q9y5b8]	Low confidence	210.796	202.935	1.03874
348	adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]	High confidence	242.14	265.696	1.09728
	spartin; trans-activated by hepatitis c virus core protein 1. [refseq;acc:nm_015087]	Low confidence	210.796	202.935	1.03874
349	adapter-related protein complex 2 alpha 2 subunit (alpha-adaptin c) (clathrin assembly protein complex 2 alpha-c large chain) (100 kda coated vesicle protein c) (plasma membrane adaptor ha2/ap2 adaptin alpha c subunit) (huntingtin-interacting protein hypj). [swissprot;acc:o94973]		204.762	197.135	1.03869
	surfeit locus protein 5. [swissprot;acc:q15528]	High confidence	242.14	265.696	1.09728
350	fuse-binding protein-interacting repressor isoform b; siah binding protein 1; pyrimidine tract binding splicing factor; ro ribonucleoprotein-binding protein 1; poly-u binding splicing factor puf60. [refseq;acc:nm_014281]	Low confidence	204.762	197.135	1.03869
	zinc finger protein 291. [swissprot;acc:q9by12]	High confidence	242.14	265.696	1.09728

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.