MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	green	Interaction Map	Value Type	Network Comparison Type	red	Filtered	network_comparison

Results: HTML CSV LaTeX

Showing element 101 to 150 of 1892 in total

green  : 0
Interaction Map  : High confidence
Network Comparison Type  : Subtracted
red  : 0
Filtered  : 1
network_comparison  : 0

Rank	description	Value Type
2781	exocyst complex component exo70. [swissprot;acc:q9upt5]	Measured
		Ranked
		Squared
		Rooted
2782	vacuolar atp synthase membrane sector associated protein m8-9 (v-atpase m8.9 subunit). [swissprot;acc:o75787]	Measured
		Ranked
		Squared
		Rooted
2783	mab-21-like protein 2; mab-21-like 2. [refseq;acc:nm_006439]	Measured
		Ranked
		Squared
		Rooted
2784	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]	Measured
		Ranked
		Squared
		Rooted
2785	nucleophosmin (npm) (nucleolar phosphoprotein b23) (numatrin) (nucleolar protein no38). [swissprot;acc:p06748]	Measured
		Ranked
		Squared
		Rooted
2786	mab-21-like protein 1; mab-21-like 1. [refseq;acc:nm_005584]	Measured
		Ranked
		Squared
		Rooted
2787	high mobility group protein 4-like (hmg-4l). [swissprot;acc:q9uj13]	Measured
		Ranked
		Squared
		Rooted
2788	a-kinase anchor protein 5 (a-kinase anchor protein 79 kda) (akap 79) (camp-dependent protein kinase regulatory subunit ii high affinity binding protein) (h21). [swissprot;acc:p24588]	Measured
		Ranked
		Squared
		Rooted
2789	protein-tyrosine phosphatase, non-receptor type 11 (ec 3.1.3.48) (protein-tyrosine phosphatase 2c) (ptp-2c) (ptp-1d) (sh-ptp3) (sh- ptp2) (shp-2). [swissprot;acc:q06124]	Measured
		Ranked
		Squared
		Rooted
2790	transcription factor mafb (v-maf musculoaponeurotic fibrosarcoma oncogene homolog b). [swissprot;acc:q9y5q3]	Measured
		Ranked
		Squared
		Rooted
2791	cytochrome c oxidase polypeptide va, mitochondrial precursor (ec 1.9.3.1). [swissprot;acc:p20674]	Measured
		Ranked
		Squared
		Rooted
2792	transcription factor maf (proto-oncogene c-maf). [swissprot;acc:o75444]	Measured
		Ranked
		Squared
		Rooted
2793	udp-glucuronosyltransferase 2b17 precursor, microsomal (ec 2.4.1.17) (udpgt) (c19-steroid specific udp-glucuronosyltransferase). [swissprot;acc:o75795]	Measured
		Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.