MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 101 to 150 of 8289 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1

Rank	description	Interaction Map	red	green	network_comparison
51	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	Low confidence	234.802	260.98	1.11149
	spermatogenesis associated 6. [refseq;acc:nm_019073]	High confidence	133	105	1.26667
52	amp deaminase 2 (ec 3.5.4.6) (amp deaminase isoform l). [swissprot;acc:q01433]
	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [swissprot;acc:o60906]	Low confidence	234.802	260.98	1.11149
53	db83 protein. [swissprot;acc:p57088]
	transcription factor jun-b. [swissprot;acc:p17275]	High confidence	201.144	158.868	1.26611
54	cytoplasmic polyadenylation element binding protein 3. [refseq;acc:nm_014912]	Low confidence	267.448	240.822	1.11056
	transcription factor jun-d. [swissprot;acc:p17535]	High confidence	200.941	158.941	1.26425
55	cytoplasmic polyadenylation element binding protein 4. [refseq;acc:nm_030627]	Low confidence	267.376	240.78	1.11046
	protein kinase, interferon-inducible double stranded rna dependent activator; protein activator of the interferon-induced protein kinase. [refseq;acc:nm_003690]	High confidence	320.927	254.434	1.26134
56	brachyury protein (t protein). [swissprot;acc:o15178]	Low confidence	224.922	202.592	1.11022
	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-7 subunit. [swissprot;acc:o60262]	High confidence	266.856	336.233	1.25998
57	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-12 subunit. [swissprot;acc:q9ubi6]
	proto-oncogene protein c-fos (cellular oncogene fos) (g0/g1 switch regulatory protein 7). [swissprot;acc:p01100]	Low confidence	202.802	182.73	1.10985
58	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150]	High confidence	266.863	336.191	1.25979
	jun dimerization protein. [refseq;acc:nm_130469]	Low confidence	202.802	182.73	1.10985
59	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-3 subunit. [swissprot;acc:p29798]	High confidence	266.863	336.19	1.25978
	nadh-ubiquinone oxidoreductase subunit b17.2 (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b17.2) (ci-b17.2) (cib17.2) (13 kda differentiation-associated protein). [swissprot;acc:q9ui09]	Low confidence	233.134	210.267	1.10875
60	fos-related antigen 2. [swissprot;acc:p15408]		202.793	182.961	1.10839
	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-8 subunit (gamma-9). [swissprot;acc:q9uk08]	High confidence	266.864	336.184	1.25976
61	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 subunit. [swissprot;acc:p30670]			336.182	1.25975
	protein fosb (g0/g1 switch regulatory protein 3). [swissprot;acc:p53539]	Low confidence	202.792	182.974	1.10831
62	fos-related antigen 1 (fra-1). [swissprot;acc:p15407]		202.79	183.017	1.10804
	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-10 subunit. [swissprot;acc:p50151]	High confidence	266.865	336.181	1.25974
63	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8]			336.178	1.25973
	putative rna-binding protein 7 (rna binding motif protein 7). [swissprot;acc:q9y580]	Low confidence	265.688	239.902	1.10749
64	guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-11 subunit. [swissprot;acc:p50152]	High confidence	266.868	336.159	1.25965
	transcription factor jun-d. [swissprot;acc:p17535]	Low confidence	202.709	183.361	1.10552
65	guanine nucleotide-binding protein g(q), alpha subunit. [swissprot;acc:p50148]	High confidence	267.136	336.077	1.25807
	transcription factor jun-b. [swissprot;acc:p17275]	Low confidence	202.728	183.388	1.10546
66	guanine nucleotide-binding protein g(y), alpha subunit (alpha-11). [swissprot;acc:p29992]	High confidence	267.136	336.077	1.25807
	mitochondrial tumor suppressor gene 1; transcription factor mtsg1; at2 receptor-interacting protein 1; erythroid differentiation-related gene. [refseq;acc:nm_020749]	Low confidence	221.902	200.783	1.10518
67	guanine nucleotide-binding protein g(t), alpha-2 subunit (transducin alpha-2 chain). [swissprot;acc:p19087]	High confidence	267.14	336.075	1.25805
	retinoblastoma-associated factor 600. [refseq;acc:nm_020765]	Low confidence	165.535	149.799	1.10505
68	60s ribosomal protein l37a. [swissprot;acc:p12751]		239.692	217.005	1.10455
	guanine nucleotide-binding protein g(z), alpha subunit (g(x) alpha chain) (gz-alpha). [swissprot;acc:p19086]	High confidence	267.139	336.075	1.25805
69	guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [swissprot;acc:p11488]		267.14
	testis-specific protein tex28. [swissprot;acc:o15482]	Low confidence	259.517	235.017	1.10425
70	27 kda golgi snare protein (golgi snap receptor complex member 2) (membrin). [swissprot;acc:o14653]
	guanine nucleotide-binding protein g(i), alpha-2 subunit (adenylate cyclase-inhibiting g alpha protein). [swissprot;acc:p04899]	High confidence	267.142	336.074	1.25804
71	cysteine-rich protein 1 (cysteine-rich intestinal protein) (crip) (cysteine-rich heart protein) (hcrhp). [swissprot;acc:p50238]	Low confidence	230.944	209.149	1.10421
	guanine nucleotide-binding protein g(i), alpha-1 subunit (adenylate cyclase-inhibiting g alpha protein). [swissprot;acc:p04898]	High confidence	267.144	336.073	1.25802
72	guanine nucleotide-binding protein g(k), alpha subunit (g(i) alpha-3). [swissprot;acc:p08754]
	set and mynd domain containing 2; hskm-b protein; zinc finger, mynd domain containing 14. [refseq;acc:nm_020197]	Low confidence	230.944	209.149	1.10421
73	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	High confidence	288	362	1.25694
	set and mynd domain containing protein 1. [sptrembl;acc:q8nb12]	Low confidence	230.944	209.149	1.10421
74	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	High confidence	288	362	1.25694
	putative adenosylhomocysteinase 2 (ec 3.3.1.1) (s-adenosyl-l- homocysteine hydrolase) (adohcyase). [swissprot;acc:o43865]	Low confidence	195.817	215.516	1.1006
75	nipsnap2 protein (glioblastoma amplified sequence). [swissprot;acc:o75323]		249.709	226.944	1.10031
	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [swissprot;acc:o60906]	High confidence	288	362	1.25694

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.