MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	Hugo	Network Comparison Type	Value Type	description	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1 to 8 of 8 in total

Hugo  : PSCD4
Network Comparison Type  : Divided
description  : cytohesin 4. [swissprot;acc:q9uia0]
Filtered  : 1

Rank	Value Type	Interaction Map	red	network_comparison	green
5	Ranked	High confidence	15	1.86667	28
62	Squared	Low confidence	92262.9	1.29219	71400.2
106		High confidence	407289	1.54656	263351
174	Measured	Low confidence	12315	1.08115	11390.6
223		High confidence	41482.5	1.24361	33356.5
304	Rooted		203.673	1.11517	182.638
4867		Low confidence	88.8786	1.01242	87.7882
4997	Ranked		177.9	1.00031	177.845

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.