MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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green	description	Rank	Filtered	Gene	Value Type	Interaction Map	network_comparison	red	Network Comparison Type

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Showing element 451 to 500 of 38536 in total

green  : 0.00001
Filtered  : 1
network_comparison  : 1
red  : 0.00001
Network Comparison Type  : Divided

description	Rank	Value Type	Interaction Map
double-stranded rna-binding zinc finger protein jaz. [refseq;acc:nm_012279]	3054	Ranked	High confidence
		Squared
		Rooted
	5047	Ranked	Low confidence
	5048	Measured
		Squared
		Rooted
doublesex and mab-3 related transcription factor 3; testis-specific protein; dmrt-like family a3. [refseq;acc:nm_021240]	3187	Measured	High confidence
		Ranked
		Squared
		Rooted
dual specificity protein phosphatase 11 (ec 3.1.3.48) (rna/rnp complex-intereracting phosphatase) (phosphatase that interacts with rna/rnp complex 1). [swissprot;acc:o75319]	2926	Measured
		Ranked
		Squared
		Rooted
dynein 2 light intermediate chain. [refseq;acc:nm_016008]	2962	Measured
		Ranked
		Squared
		Rooted
dynein intermediate chain 1, axonemal (axonemal dynein intermediate chain 1). [swissprot;acc:q9ui46]	3029	Measured
		Ranked
		Squared
		Rooted
ecotropic virus integration 1 site protein. [swissprot;acc:q03112]	3170	Measured
		Ranked
		Squared
		Rooted
ell-associated factor 2; uncharacterized bone marrow protein bm040; testosterone regulated apoptosis inducer and tumor suppressor. [refseq;acc:nm_018456]	2921	Measured
		Ranked
		Squared
		Rooted
elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897]	3027	Measured
		Ranked
		Squared
		Rooted
endosome-associated fyve-domain protein. [refseq;acc:nm_014733]	3200	Measured
		Ranked
		Squared
		Rooted
enhancer of zeste homolog 1 (enx-2). [swissprot;acc:q92800]	3090	Measured
		Ranked
		Squared
		Rooted
enhancer of zeste homolog 2 (enx-1). [swissprot;acc:q15910]	3098	Measured
		Ranked
		Squared
		Rooted
ergic-53 protein precursor (er-golgi intermediate compartment 53 kda protein) (lectin, mannose-binding 1) (gp58) (intracellular mannose specific lectin mr60). [swissprot;acc:p49257]	3177	Measured
		Ranked
		Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.