MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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green	description	Value Type	Gene	Rank	Network Comparison Type	Interaction Map	Filtered	red	network_comparison

Results: HTML CSV LaTeX

Showing element 501 to 550 of 12912 in total

green  : 0.00001
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1
red  : 0.00001
network_comparison  : 1

description	Value Type	Rank
fibrillin 3. [refseq;acc:nm_032447]	Measured	2939
	Ranked
	Squared
	Rooted
flap endonuclease-1 (ec 3.-.-.-) (maturation factor 1) (mf1). [swissprot;acc:p39748]	Measured	2831
	Ranked
	Squared
	Rooted
fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075]	Measured	2907
	Ranked
	Squared
	Rooted
fructose-bisphosphate aldolase b (ec 4.1.2.13) (liver-type aldolase). [swissprot;acc:p05062]	Measured	2973
	Ranked
	Squared
	Rooted
fructose-bisphosphate aldolase c (ec 4.1.2.13) (brain-type aldolase). [swissprot;acc:p09972]	Measured	3087
	Ranked
	Squared
	Rooted
fyve-finger-containing rab5 effector protein rabenosyn-5. [refseq;acc:nm_022340]	Measured	2998
	Ranked
	Squared
	Rooted
g protein-coupled receptor 66. [refseq;acc:nm_006056]	Measured	2815
	Ranked
	Squared
	Rooted
gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284]	Measured	3101
	Ranked
	Squared
	Rooted
gdp-fucose protein o-fucosyltransferase 1 precursor (ec 2.4.1.221) (peptide o-fucosyltransferase) (o-fuct-1). [swissprot;acc:q9h488]	Measured	3125
	Ranked
	Squared
	Rooted
geranylgeranyl transferase type ii beta subunit (ec 2.5.1.-) (rab geranylgeranyltransferase beta subunit) (rab geranyl- geranyltransferase beta subunit) (rab gg transferase beta) (rab ggtase beta). [swissprot;acc:p53611]	Measured	2963
	Ranked
	Squared
	Rooted
glioma pathogenesis-related protein (glipr) (rtvp-1 protein). [swissprot;acc:p48060]	Measured	2953
	Ranked
	Squared
	Rooted
glioma tumor suppressor candidate region gene 2 protein (p60). [swissprot;acc:q9nzm5]	Measured	3104
	Ranked
	Squared
	Rooted
glioma-amplified sequence-41; numa binding protein 1. [refseq;acc:nm_006530]	Measured	3007
	Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.