MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	Hugo	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 601 to 650 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	Hugo	description	Network Comparison Type	red	green	network_comparison
301	ALG1	beta-1,4 mannosyltransferase. [refseq;acc:nm_019109]	Divided	150.982	166.372	1.10193
	MAGED4	melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801]	Subtracted	88.2482	110.265	22.0168
302	MAGEE2	hepatocellular carcinoma-associated protein hca3. [refseq;acc:nm_138703]
	RPL26	60s ribosomal protein l26. [swissprot;acc:q02877]	Divided	242.326	267.008	1.10185
303	no value	melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]	Subtracted	88.2482	110.265	22.0168
	RPL35	60s ribosomal protein l35. [swissprot;acc:p42766]	Divided	242.333	266.999	1.10179
304	no value	40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]		242.339	266.986	1.1017
	MAGEA11	melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]	Subtracted	88.2482	110.265	22.0168
305	MAGEA2B	melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]
	MRPL2	mitochondrial ribosomal protein l2. [refseq;acc:nm_015950]	Divided	242.339	266.986	1.1017
306	no value	60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]		242.153	266.673	1.10126
		hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]	Subtracted	88.2482	110.265	22.0168
307	MAGEA6	melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]
	SRR	serine racemase (ec 5.1.1.-). [swissprot;acc:q9gzt4]	Divided	242.153	266.673	1.10126
308	NDN	necdin. [swissprot;acc:q99608]	Subtracted	88.2482	110.265	22.0168
	RPL34	60s ribosomal protein l34. [swissprot;acc:p49207]	Divided	242.153	266.673	1.10126
309	MAGED1	melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]	Subtracted	88.2482	110.265	22.0168
	SEC61A2	protein transport protein sec61 alpha subunit isoform 2 (sec61 alpha- 2). [swissprot;acc:q9y2r3]	Divided	242.153	266.673	1.10126
310	MAGEF1	melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]	Subtracted	88.2482	110.265	22.0168
	SEC61A1	protein transport protein sec61 alpha subunit isoform 1 (sec61 alpha- 1). [swissprot;acc:p38378]	Divided	242.153	266.673	1.10126
311	EIF1B	protein translation factor sui1 homolog gc20. [swissprot;acc:o60739]		242.627	267.151	1.10108
	MAGEB6B	melanoma antigen, family b, 6. [refseq;acc:nm_173523]	Subtracted	88.2482	110.265	22.0168
312	no value	melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]
	RPL3L	60s ribosomal protein l3-like. [swissprot;acc:q92901]	Divided	242.195	266.663	1.10103
313	MAGEA9	melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]	Subtracted	88.2482	110.265	22.0168
	RRM2B	ribonucleotide reductase m2 b (tp53 inducible); p53-inducible ribonucleotide reductase small subunit 2 homolog. [refseq;acc:nm_015713]	Divided	232.473	211.207	1.10069
314	MAGEA8	melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]	Subtracted	88.2482	110.265	22.0168
	METAP1	methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582]	Divided	244.126	268.604	1.10027
315	MAGEC1	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]	Subtracted	88.2482	110.265	22.0168
	METAP2	methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579]	Divided	244.126	268.604	1.10027
316	EIF1	protein translation factor sui1 homolog (sui1iso1). [swissprot;acc:p41567]		242.694	267.017	1.10022
	MAGEA4	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]	Subtracted	88.2482	110.265	22.0168
317	no value	melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]
		splicing factor 3b subunit 3 (spliceosome associated protein 130) (sap 130) (sf3b130) (pre-mrna splicing factor sf3b 130 kda subunit). [swissprot;acc:q15393]	Divided	224.445	204.044	1.09998
318	MAGEA10	melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]	Subtracted	88.2482	110.265	22.0168
	MRPL3	mitochondrial 60s ribosomal protein l3 (l3mt). [swissprot;acc:p09001]	Divided	242.011	266.18	1.09987
319	MAGEB4	melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]	Subtracted	88.2482	110.265	22.0168
	RPL19	60s ribosomal protein l19. [swissprot;acc:p14118]	Divided	240.73	264.729	1.09969
320	CDH1	epithelial-cadherin precursor (e-cadherin) (uvomorulin) (cadherin-1) (cam 120/80). [swissprot;acc:p12830]		241.892	265.96	1.0995
	MAGED2	melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1]	Subtracted	88.2482	110.265	22.0168
321	no value	c367g8.3 (novel protein similar to rpl23a (60s ribosomal protein l23a)) (60s ribosomal protein l23a like). [sptrembl;acc:q9br02]	Divided	241.892	265.959	1.09949
	TRO	trophinin. [swissprot;acc:q12816]	Subtracted	88.2482	110.265	22.0168
322	DNASE2B	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]	Divided	86.7483	78.8995	1.09948
	RRM2	ribonucleoside-diphosphate reductase m2 chain (ec 1.17.4.1) (ribonucleotide reductase small chain). [swissprot;acc:p31350]	Subtracted	231.969	210.064	21.905
323	no value	60s ribosomal protein l23a. [swissprot;acc:p29316]	Divided	241.884	265.945	1.09947
	RPS14	40s ribosomal protein s14 (pro2640). [swissprot;acc:p06366]	Subtracted	242.238	264.11	21.872
324	no value	40s ribosomal protein s18 (ke-3) (ke3). [swissprot;acc:p25232]
	RPS23	40s ribosomal protein s23. [swissprot;acc:p39028]	Divided	243.944	268.195	1.09941
325	MRPL13	60s ribosomal protein l13, mitochondrial (l13mt). [swissprot;acc:q9byd1]	Subtracted	241.828	263.62	21.792
	MRPS12	28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235]	Divided	243.944	268.195	1.09941

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.