MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Value Type	Filtered	Interaction Map	Network Comparison Type	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 3682 to 3731 of 19268 in total

Value Type  : Measured

description	Rank	Filtered	Interaction Map	Network Comparison Type	red	network_comparison	green
cop9 complex subunit 7a; cop9 (constitutive photomorphogenic, arabidopsis, homolog) subunit 7a. [refseq;acc:nm_016319]	3332	1	Low confidence	Divided	7996.92	1.0267	8210.43
cop9 constitutive photomorphogenic homolog subunit 3; cop9 complex subunit 3; jab1-containing signalosome subunit 3. [refseq;acc:nm_003653]	264		High confidence		4987.58	1.2181	4094.57
	448			Subtracted		893.01
	3176		Low confidence	Divided	7797.64	1.02737	8011.03
	3313			Subtracted		213.39
cop9 constitutive photomorphogenic homolog subunit 5; jun activation domain-binding protein. [refseq;acc:nm_006837]	2114		High confidence		6773.67	301.84	7075.51
	2206		Low confidence	Divided	7864.03	1.03139	8110.9
	2298			Subtracted		246.87
	2330		High confidence	Divided	6773.67	1.04456	7075.51
cop9 constitutive photomorphogenic homolog subunit 7b; likely ortholog of cop9 (constitutive photomorphogenic), subunit 7b (arabidopsis); cop9 (constitutive photomorphogenic, arabidopsis, homolog) subunit 7b. [refseq;acc:nm_022730]	3340		Low confidence	Subtracted	7997.29	212.86	8210.15
	3356			Divided		1.02662
cop9 signalosome complex subunit 1 (g protein pathway suppressor 1) (gps1 protein) (mfh protein). [swissprot;acc:q13098]	146	0	High confidence	Subtracted	17356	230	17126
	325		Low confidence		8820	152	8668
	456		High confidence	Divided	17356	1.01343	17126
	702		Low confidence		8820	1.01754	8668
	2827	1	High confidence		0.00001	1	0.00001
				Subtracted	0	0	0
	3174		Low confidence	Divided	7797.64	1.02737	8011.03
	3311			Subtracted		213.39
cop9 signalosome complex subunit 2 (signalosome subunit 2) (sgn2) (thyroid receptor interacting protein 15) (trip15). [swissprot;acc:q15647]	2841		High confidence	Divided	0.00001	1	0.00001
				Subtracted	0	0	0
	3175		Low confidence	Divided	7797.64	1.02737	8011.03
	3312			Subtracted		213.39
cop9 subunit 6 (mov34 homolog, 34 kd). [refseq;acc:nm_006833]	2108		High confidence		6773.67	301.84	7075.51
	2324			Divided		1.04456
	2423		Low confidence		7904.53	1.03061	8146.48
	2436			Subtracted		241.95
copper chaperone for superoxide dismutase (superoxide dismutase copper chaperone). [swissprot;acc:o14618]	2027			Divided	7780.94	1.03204	8030.23
	2217			Subtracted		249.29
copper-transporting atpase 1 (ec 3.6.3.4) (copper pump 1) (menkes disease-associated protein). [swissprot;acc:q04656]	610				8631.91	361.25	8993.16
	765			Divided		1.04185
	1711		High confidence	Subtracted	5941.29	398.64	6339.93
	1752			Divided		1.0671
copper-transporting atpase 2 (ec 3.6.3.4) (copper pump 2) (wilson disease-associated protein). [swissprot;acc:p35670]	584		Low confidence	Subtracted	8644.06	366.89	9010.95
	736			Divided		1.04244
	1712		High confidence	Subtracted	5941.83	398.49	6340.32
	1754			Divided		1.06707
coproporphyrinogen iii oxidase, mitochondrial precursor (ec 1.3.3.3) (coproporphyrinogenase) (coprogen oxidase) (cox). [swissprot;acc:p36551]	2686			Subtracted	7913.63	26.31	7939.94
	2734			Divided		1.00332
	3400		Low confidence	Subtracted	8072.49	210.54	8283.03
	3482			Divided		1.02608
core promoter element-binding protein (kruppel-like factor 6) (b-cell derived protein 1) (proto-oncogene bcd1) (transcription factor zf9) (gc-rich sites binding factor gbf). [swissprot;acc:q99612]	3964			Subtracted	9140.87	180.81	9321.68
	4246			Divided		1.01978
core-binding factor, beta subunit (cbf-beta) (polyomavirus enhancer binding protein 2 beta subunit) (pebp2-beta) (pea2-beta) (sl3-3 enhancer factor 1 beta subunit) (sl3/akv core-binding factor beta subunit). [swissprot;acc:q13951]	3183		High confidence		0.00001	1	0.00001
				Subtracted	0	0	0
	5059		Low confidence	Divided	0.00001	1	0.00001
				Subtracted	0	0	0
core1 udp-galactose:n-acetylgalactosamine-alpha-r beta 1,3-galac. [refseq;acc:nm_020156]	151				10492.4	687.67	9804.73
	214			Divided		1.07014
coronin 1b (coronin 2). [swissprot;acc:q9br76]	2595			Subtracted	7985.56	236.85	8222.41

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.