MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Value Type	Gene	description	Network Comparison Type	Filtered	Interaction Map	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 9634 in total

Value Type  : Ranked
Network Comparison Type  : Divided

Rank	description	Filtered	Interaction Map	red	green	network_comparison
13	protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8]	1	High confidence	288.754	212.554	1.3585
	sorbitol dehydrogenase (ec 1.1.1.14) (l-iditol 2-dehydrogenase). [swissprot;acc:q00796]	0	Low confidence	7435.56	12191.6	1.63963
14	cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936]	1	High confidence	56.6768	75.3531	1.32952
	dystrophin. [swissprot;acc:p11532]	0		10232.5	18054.8	1.76446
	ptd016 protein. [refseq;acc:nm_016125]		Low confidence	18050	11234	1.60673
	vitelliform macular dystrophy 2-like protein 1. [refseq;acc:nm_017682]	1		37.9984	29.1831	1.30207
15	adenomatous polyposis coli like. [refseq;acc:nm_005883]	0		12074.1	7597.61	1.5892
	microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8]	1	High confidence	56.7244	75.3948	1.32914
	protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8]		Low confidence	255.046	202.362	1.26035
	succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial precursor (cybs) (succinate-ubiquinone reductase membrane anchor subunit) (qps2) (cii-4) (succinate dehydrogenase complex subunit d) (succinate-ubiquinone oxidoreductase cytochrome b small subunit). [swissprot;acc:o14521]	0	High confidence	19403	11267	1.72211
16	beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938]		Low confidence	7395	11625	1.57201
	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]		High confidence	12170.7	20670.6	1.69839
	microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492]	1		56.7252	75.3954	1.32913
	thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]		Low confidence	305.472	247.246	1.2355
17	cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326]		High confidence	56.7841	75.447	1.32866
	fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402]	0		11543	6812	1.69451
	gbp protein isoform a. [refseq;acc:nm_017870]	1	Low confidence	305.399	247.213	1.23537
	leucine rich repeat (in flii) interacting protein 1. [refseq;acc:nm_004735]	0		8082.33	5266.67	1.53462
18	1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	1	High confidence	185.678	245.247	1.32082
	early hematopoietic zinc finger. [refseq;acc:nm_015461]	0	Low confidence	5850.23	8903.28	1.52187
	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]		High confidence	22286	13216	1.68629
	jumonji domain containing 1; zinc finger protein; testis-specific protein a. [refseq;acc:nm_018433]	1	Low confidence	305.303	247.169	1.2352
19	glycogen phosphorylase, brain form (ec 2.4.1.1). [swissprot;acc:p11216]		High confidence	185.678	245.247	1.32082
	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]	0		22286	13216	1.68629
	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]		Low confidence	3208.8	4871.6	1.5182
	trypsin iii precursor (ec 3.4.21.4) (brain trypsinogen) (mesotrypsinogen) (trypsin iv). [swissprot;acc:p35030]	1		304.548	246.824	1.23387
20	glycogen phosphorylase, liver form (ec 2.4.1.1). [swissprot;acc:p06737]		High confidence	185.678	245.247	1.32082
	guanine nucleotide-binding protein beta subunit-like protein 1 (g protein beta-subunit like protein 1) (wd40 repeat containing protein deleted in vcfs) (wdvcf protein) (fksg1 protein) (dgcrk3). [swissprot;acc:q9byb4]	0	Low confidence	22422	14964	1.4984
	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]		High confidence	22286	13216	1.68629
	trypsin i precursor (ec 3.4.21.4) (cationic trypsinogen). [swissprot;acc:p07477]	1	Low confidence	304.359	246.737	1.23354
21	acrc protein; putative nuclear protein. [refseq;acc:nm_052957]	0	High confidence	6313.38	10621.4	1.68236
	dj570f3.6 (novel protein similar to lysophospholipase ii (lypla2)). [sptrembl;acc:q9uge0]		Low confidence	3859	2582	1.49458
	myosin xv (unconventional myosin-15). [swissprot;acc:q9ukn7]	1	High confidence	185.678	245.247	1.32082
	phosphatidylinositol-glycan biosynthesis, class f protein (pig-f). [swissprot;acc:q07326]		Low confidence	198	163	1.21472
22	cathepsin z precursor (ec 3.4.22.-) (cathepsin x) (cathepsin p). [swissprot;acc:q9ubr2]	0		11515	7867	1.46371
	glycogen phosphorylase, muscle form (ec 2.4.1.1) (myophosphorylase). [swissprot;acc:p11217]	1	High confidence	185.678	245.247	1.32082
	n33 protein. [swissprot;acc:q13454]		Low confidence	198	163	1.21472
	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]	0	High confidence	20989	12479	1.68195
23	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	1		58	44	1.31818
	hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate. [refseq;acc:nm_004712]	0		15520.4	9285.44	1.67148
	implantation-associated protein. [refseq;acc:nm_032121]	1	Low confidence	198	163	1.21472
	serpin b12. [swissprot;acc:q96p63]	0		14604.2	21138.6	1.44743
24	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]		High confidence	13730.5	8257	1.66289
	histidine triad nucleotide-binding protein 1 (adenosine 5'- monophosphoramidase) (protein kinase c inhibitor 1) (protein kinase c- interacting protein 1) (pkci-1). [swissprot;acc:p49773]	1	Low confidence	188.298	228.509	1.21355
	hurpin (hacat uv-repressible serpin) (protease inhibitor 13) (headpin) (serpin b13). [swissprot;acc:q9uiv8]	0		14592	21113.7	1.44694
	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]	1	High confidence	58	44	1.31818
25	25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]		Low confidence	286.396	238.476	1.20094
	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]	0	High confidence	13730.5	8257	1.66289
	nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718]		Low confidence	9830	6909	1.42278
	pantothenate kinase 2, mitochondrial precursor (ec 2.7.1.33) (pantothenic acid kinase 2) (hpank2). [swissprot;acc:q9bz23]	1	High confidence	58	44	1.31818

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.