MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	description	Value Type	Network Comparison Type	red	Filtered	Interaction Map	network_comparison	green

Results: HTML CSV LaTeX

Showing element 951 to 1000 of 9634 in total

Value Type  : Ranked
Network Comparison Type  : Divided

Rank	description	red	Filtered	Interaction Map	network_comparison	green
238	rd protein. [swissprot;acc:p18615]	227.357	1	High confidence	1.11785	254.15
	similar to zinc finger protein 85 (zinc finger protein hpf4) (htf1). [refseq;acc:nm_145287]	4256.39	0	Low confidence	1.14024	4853.29
239	dual oxidase 2 precursor; dual oxidase-like domains 2; nicotinamide adenine dinucleotide phosphate oxidase; flavoprotein nadph oxidase; nadph thyroid oxidase 2; nadh/nadph thyroid oxidase p138-tox; nadph oxidase/peroxidase duox2. [refseq;acc:nm_014080]	210.504	1		1.04684	201.086
	glutathione transferase omega 1 (ec 2.5.1.18) (gsto 1-1). [swissprot;acc:p78417]	227.357		High confidence	1.11785	254.15
	mto1 protein homolog (cgi-02). [swissprot;acc:q9y2z2]	8907.41	0		1.09969	9795.36
	similar to zinc finger protein 136. [refseq;acc:nm_145295]	4256.39		Low confidence	1.14024	4853.29
240	androgen-induced 1; cgi-103 protein; androgen induced protein. [refseq;acc:nm_016108]	227.357	1	High confidence	1.11785	254.15
	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	162.755		Low confidence	1.04682	155.476
	methyltransferase like 2. [refseq;acc:nm_018396]	17946	0	High confidence	1.09923	16326
	similar to dna-binding protein; zinc finger protein 253. [refseq;acc:nm_145297]	4256.39		Low confidence	1.14024	4853.29
241	atp synthase b chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p24539]	227.357	1	High confidence	1.11785	254.15
	homeobox protein hox-b4 (hox-2f) (hox-2.6). [swissprot;acc:p17483]	162.755		Low confidence	1.04682	155.476
	secreted modular calcium-binding protein 1. [refseq;acc:nm_022137]	14003.7	0	High confidence	1.09891	12743.3
	zinc finger protein 132. [swissprot;acc:p52740]	4256.15		Low confidence	1.14024	4853.03
242	1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	15260.6		High confidence	1.09822	13895.8
	homeobox protein hox-c5 (hox-3d) (cp11). [swissprot;acc:q00444]	162.755	1	Low confidence	1.04682	155.476
	j domain containing protein 1. [swissprot;acc:q9ukb3]	227.357		High confidence	1.11785	254.15
	zinc finger protein 84 (zinc finger protein hpf2). [swissprot;acc:p51523]	4256.39	0	Low confidence	1.14024	4853.29
243	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]	162.755	1		1.04682	155.476
	polyadenylate-binding protein 3 (poly(a)-binding protein 3) (pabp 3) (testis-specific poly(a)-binding protein). [swissprot;acc:q9h361]	1251	0	High confidence	1.09752	1373
	sorting nexin 13 (rgs domain- and phox domain-containing protein) (rgs-px1). [swissprot;acc:q9y5w8]	227.357	1		1.11785	254.15
	zinc finger protein 121 (zinc finger protein 20) (fragment). [swissprot;acc:p58317]	4256.71	0	Low confidence	1.14023	4853.62
244	ba127l20.1 (novel glutathione-s-transferase). [sptrembl;acc:q9h4y5]	227.357	1	High confidence	1.11785	254.15
	homeobox protein hox-d4 (hox-4b) (hox-5.1) (hho.c13). [swissprot;acc:p09016]	162.755		Low confidence	1.04682	155.476
	keratin associated protein 9.2. [refseq;acc:nm_031961]	10551.1	0	High confidence	1.09751	11579.9
	zinc finger protein af020591. [refseq;acc:nm_014480]	4256.94		Low confidence	1.14023	4853.87
245	cell division protein kinase 3 (ec 2.7.1.-). [swissprot;acc:q00526]	11867.6		High confidence	1.09702	13019
	homeobox protein hox-b5 (hox-2a) (hho.c10) (hu-1). [swissprot;acc:p09067]	162.755	1	Low confidence	1.04682	155.476
	small nuclear ribonucleoprotein sm d3 (snrnp core protein d3) (sm-d3). [swissprot;acc:p43331]	226.109		High confidence	1.11751	202.333
	zinc finger protein 20 (zinc finger protein kox13) (dkfzp572p0920). [swissprot;acc:p17024]	4256.94	0	Low confidence	1.14023	4853.87
246	eukaryotic translation initiation factor 4 gamma, 3. [refseq;acc:nm_003760]	237.312	1	High confidence	1.11748	212.363
	homeobox protein hox-a5 (hox-1c). [swissprot;acc:p20719]	162.755		Low confidence	1.04682	155.476
	keratin associated protein 4.3 (fragment). [sptrembl;acc:q9byr4]	10551.6	0	High confidence	1.09687	11573.7
	zinc finger protein 11b (fragment). [swissprot;acc:q06732]	4256.55		Low confidence	1.14023	4853.45
247	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]	162.755	1		1.04682	155.476
	keratin associated protein 2-4; keratin associated protein 2.4. [refseq;acc:nm_033184]	10551.6	0	High confidence	1.09687	11573.7
	rna-binding protein. [refseq;acc:nm_019027]	237.302	1		1.11719	212.41
	zinc finger protein 208. [swissprot;acc:o43345]	4256.94	0	Low confidence	1.14023	4853.87
248	apobec-1 complementation factor isoform 1; apobec-1 stimulating protein; apo-b rna editing protein. [refseq;acc:nm_014576]	237.302	1	High confidence	1.11719	212.41
	keratin associated protein 1.5. [refseq;acc:nm_031957]	10551.6	0		1.09687	11573.7
	retinal short-chain dehydrogenase/reductase 3. [refseq;acc:nm_016246]	162.755	1	Low confidence	1.04682	155.476
	zinc finger protein 136. [swissprot;acc:p52737]	4256.71	0		1.14023	4853.62
249	dual oxidase 1 precursor; nadph thyroid oxidase 1; flavoprotein nadph oxidase; nicotinamide adenine dinucleotide phosphate oxidase. [refseq;acc:nm_017434]	210.487	1		1.0468	201.076
	gonadotropin inducible transcription repressor-1 (giot-1). [swissprot;acc:q8taf7]	4257.1	0		1.14022	4854.04
	keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [swissprot;acc:p26371]	10551.6		High confidence	1.09687	11573.7
	ns1-associated protein 1. [refseq;acc:nm_006372]	237.302	1		1.11719	212.41
250	diacylglycerol o-acyltransferase 1 (ec 2.3.1.20) (diglyceride acyltransferase) (acat related gene product 1). [swissprot;acc:o75907]	210.443		Low confidence	1.04671	201.051
	heterogeneous nuclear ribonucleoprotein r (hnrnp r). [swissprot;acc:o43390]	237.302		High confidence	1.11719	212.41
	keratin associated protein 1-3; keratin associated protein 1.3. [refseq;acc:nm_030966]	10551.6	0		1.09687	11573.7
	zinc finger protein 85 (zinc finger protein hpf4) (htf1). [swissprot;acc:q03923]	4257.26		Low confidence	1.14022	4854.21

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.