MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	green	Value Type	Filtered	Interaction Map	Network Comparison Type	network_comparison	red

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Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

description	Rank	green	Value Type	Filtered	Interaction Map	network_comparison	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	18	245.247	Ranked	1	High confidence	1.32082	185.678
	37	934.348	Measured	0		2.79409	334.401
		1034.13	Squared			10.2338	101.05
	53	18.0183	Rooted			1.5213	11.844
	60	2765.82	Measured	1		1.6231	4489.19
	64	47.2654	Rooted			1.35128	63.8686
	131	851.77	Measured	0	Low confidence	1.31954	645.504
	146	1268.51	Squared			1.63527	775.72
	242	13895.8	Ranked		High confidence	1.09822	15260.6
	245	6768.05	Squared	1		1.31131	8875.01
	537	17.0804	Rooted	0	Low confidence	1.04801	16.298
	629	13590.3	Ranked			1.02915	13205.3
	1119	41688.5	Squared	1		1.04654	43628.5
	4130	201.5	Ranked			1.01062	199.383
	4914	72.6287	Rooted			1.00944	71.9496
		7900.54	Measured			1.00597	7853.62
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	295	39351.7	Squared		High confidence	1.27733	30807.7
	509	8630.06	Measured			1.14278	7551.8
	805	79.1513	Rooted			1.0645	74.3557
	885	8585.64	Measured		Low confidence	1.03993	8255.95
	1038	181.041	Ranked		High confidence	1.03148	186.741
	1092	76.3375	Rooted		Low confidence	1.0386	73.5001
	1328	194.038	Ranked			1.02218	198.342
	4562	45736	Squared			1.01928	46617.7
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	294	39383.9			High confidence	1.2776	30826.5
	508	8636.87	Measured			1.14293	7556.75
	804	79.1931	Rooted			1.0646	74.3877
	880	8587.03	Measured		Low confidence	1.04001	8256.68
	1032	180.943	Ranked		High confidence	1.03162	186.664
	1084	76.3467	Rooted		Low confidence	1.03863	73.5068
	1322	194.014	Ranked			1.0222	198.322
	4569	45740.5	Squared			1.01914	46616.1
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	237	9081.29	Measured			1.06457	8530.51
	311	38866.5	Squared		High confidence	1.27154	30566.4
	378	79.5804	Rooted		Low confidence	1.04871	75.8843
	514	8532.02	Measured		High confidence	1.1411	7477
	588	185.859	Ranked		Low confidence	1.03039	191.507
	822	78.5795	Rooted		High confidence	1.06393	73.8577
	1048	182.308	Ranked			1.031	187.96
	4138	47372.8	Squared		Low confidence	1.02676	46138.2
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	252	9018.94	Measured			1.06194	8492.92
	308	38919.9	Squared		High confidence	1.27205	30596.2
	427	79.1997	Rooted		Low confidence	1.04731	75.6219
	513	8543.66	Measured		High confidence	1.14143	7485.08
	637	186.751	Ranked		Low confidence	1.029	192.166
	811	78.6514	Rooted		High confidence	1.06415	73.9102
	1043	182.137	Ranked			1.03128	187.834
	4418	47088.3	Squared		Low confidence	1.02256	46049.4
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]	2035	8323.04	Measured			1.03199	8065.05
	2766	74.9741	Rooted			1.03282	72.5914

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.