MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Value Type	Interaction Map	Filtered	Network Comparison Type	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1 to 50 of 19268 in total

Value Type  : Measured

description	Rank	Interaction Map	Filtered	Network Comparison Type	red	network_comparison	green
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	37	High confidence	0	Divided	334.401	2.79409	934.348
	45			Subtracted		599.947
	60		1	Divided	4489.19	1.6231	2765.82
	131	Low confidence	0		645.504	1.31954	851.77
	164	High confidence	1	Subtracted	4489.19	1723.37	2765.82
	273	Low confidence	0		645.504	206.266	851.77
	4909		1		7853.62	46.92	7900.54
	4914			Divided		1.00597
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	310	High confidence		Subtracted	7551.8	1078.26	8630.06
	509			Divided		1.14278
	780	Low confidence		Subtracted	8255.95	329.69	8585.64
	885			Divided		1.03993
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	307	High confidence		Subtracted	7556.75	1080.12	8636.87
	508			Divided		1.14293
	773	Low confidence		Subtracted	8256.68	330.35	8587.03
	880			Divided		1.04001
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	210			Subtracted	8530.51	550.78	9081.29
	237			Divided		1.06457
	319	High confidence		Subtracted	7477	1055.02	8532.02
	514			Divided		1.1411
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	230	Low confidence		Subtracted	8492.92	526.02	9018.94
	252			Divided		1.06194
	318	High confidence		Subtracted	7485.08	1058.58	8543.66
	513			Divided		1.14143
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]	1941	Low confidence		Subtracted	8065.05	257.99	8323.04
	2035			Divided		1.03199
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (ec 3.1.4.11) (phosphoinositide phospholipase c) (plc-beta-4) (phospholipase c-beta-4). [swissprot;acc:q15147]	2882				7948.01	1.02859	8175.27
	2902			Subtracted		227.26
	3126	High confidence		Divided	0.00001	1	0.00001
				Subtracted	0	0	0
10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984]	1136			Divided	5790.65	1.08864	6303.92
	1140			Subtracted		513.27
	2020	Low confidence			8130.62	255.96	8386.58
	2182			Divided		1.03148
10-formyltetrahydrofolate dehydrogenase (ec 1.5.1.6) (10-fthfdh). [swissprot;acc:o75891]	1693				7981.12	1.03323	8246.34
	1700			Subtracted		265.22
	2922	High confidence		Divided	0.00001	1	0.00001
				Subtracted	0	0	0
130 kda leucine-rich protein (lrp 130) (gp130) (leucine-rich ppr-motif containing protein). [swissprot;acc:p42704]	4071	Low confidence		Divided	7896.47	1.02166	8067.47
	4228			Subtracted		171
14-3-3 protein beta/alpha (protein kinase c inhibitor protein-1) (kcip-1) (protein 1054). [swissprot;acc:p31946]	490				8572.9	392.59	8965.49
	575			Divided		1.04579
	1411	High confidence			5812.02	1.07743	6262.07
	1422			Subtracted		450.05
14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655]	2941	Low confidence			8144.39	225.73	8370.12
	3088	High confidence		Divided	0.00001	1	0.00001
				Subtracted	0	0	0
	3095	Low confidence		Divided	8144.39	1.02772	8370.12
14-3-3 protein zeta/delta (protein kinase c inhibitor protein-1) (kcip-1) (factor activating exoenzyme s) (fas). [swissprot;acc:p29312]	498			Subtracted	8566.17	390.81	8956.98
	591			Divided		1.04562

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.