MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 882 to 931 of 8289 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Interaction Map	red	green	network_comparison
atrophin-1 (dentatorubral-pallidoluysian atrophy protein). [swissprot;acc:p54259]	1384	ATN1	High confidence	218.471	213.876	1.02148
	1438		Low confidence	203.208	198.892	1.0217
atrophin-1 interacting protein 1; activin receptor interacting protein 1; likely ortholog of mouse activin receptor interacting protein 1; atrophin-1 interacting protein a; membrane associated guanylate kinase 2; activin receptor interacting p. [refseq;acc:nm_012301]	1035	MAGI2	High confidence	221.682	228.68	1.03157
	4843		Low confidence	204.687	204.018	1.00328
attractin precursor (mahogany homolog) (dppt-l). [swissprot;acc:o75882]	3593	ATRN		202.255	199.378	1.01443
au rna-binding protein/enoyl-coenzyme a hydratase precursor; au rna-binding protein/enoyl-coenzyme a hydratase; 3-methylglutaconyl-coa hydratase; mga type i. [refseq;acc:nm_001698]	2110	AUH		198.94	195.186	1.01923
	2913		High confidence	0.00001	0.00001	1
augmenter of liver regeneration (herv1 protein). [swissprot;acc:p55789]	3272	GFER	Low confidence	192.976	189.989	1.01572
autoantigen ngp-1. [swissprot;acc:q13823]	670	GNL2	High confidence	250.302	236.817	1.05694
	1493		Low confidence	201.398	197.173	1.02143
autoantigen. [refseq;acc:nm_014329]	1524	EDC4		204.696	200.423	1.02132
autophagy protein 12-like (apg12-like). [swissprot;acc:o94817]	1729	ATG12	High confidence	187.582	190.028	1.01304
	2426		Low confidence	199.194	195.591	1.01842
autophagy protein 5-like (apg5-like) (apoptosis-specific protein). [swissprot;acc:q9h1y0]	1540	ATG5	High confidence	240.077	236.015	1.01721
	1604		Low confidence	204.216	200.037	1.02089
axin 1 (axis inhibition protein 1) (haxin). [swissprot;acc:o15169]	4018	AXIN1		203.424	201.094	1.01159
axin 2 (axis inhibition protein 2) (conductin) (axin-like protein) (axil). [swissprot;acc:q9y2t1]	4016	AXIN2
axonemal dynein light intermediate polypeptide 1 (inner dynein arm light chain, axonemal) (hp28). [swissprot;acc:o14645]	189	DNALI1		214.779	204.039	1.05264
	2003		High confidence	208.315	206.41	1.00923
b(0,+)-type amino acid transporter 1 (b(0,+)at) (glycoprotein- associated amino acid transporter b0,+at1). [swissprot;acc:p82251]	100	SLC7A9	Low confidence	200.497	185.679	1.0798
b-cell cll/lymphoma 6, member b (zinc finger protein); zinc finger protein 62. [refseq;acc:nm_181844]	1559	BCL6B	High confidence	196.191	192.996	1.01655
	2972		Low confidence	193.996	190.784	1.01684
b-cell lymphoma 3-encoded protein (bcl-3 protein). [swissprot;acc:p20749]	1565	BCL3		199.975	195.839	1.02112
	2655		High confidence	201.445	201.667	1.0011
b-cell lymphoma 6 protein (bcl-6) (zinc finger protein 51) (laz-3 protein) (bcl-5). [swissprot;acc:p41182]	1556	BCL6		196.192	192.996	1.01656
	2973		Low confidence	193.996	190.784	1.01684
b-cell receptor-associated protein 29 (bcr-associated protein bap29). [swissprot;acc:q9uhq4]	3019	BCAP29		201.261	197.953	1.01671
b-cell receptor-associated protein 31 (bcr-associated protein bap31) (p28 bap31) (cdm protein) (6c6-ag tumor-associated antigen) (dxs1357e). [swissprot;acc:p51572]	3011	BCAP31
b-lymphocyte activation-related protein. [sptrembl;acc:q96pn3]	4286	no value		197.793	195.963	1.00934
b-raf proto-oncogene serine/threonine-protein kinase (ec 2.7.1.-) (p94) (v-raf murine sarcoma viral oncogene homolog b1). [swissprot;acc:p15056]	980	BRAF	High confidence	130.289	134.713	1.03396
	4824		Low confidence	184.583	183.88	1.00382
b/k protein. [refseq;acc:nm_016524]	2533	SYT17		200.555	196.985	1.01812
b24o18.3 (pom121 membrane glycoprotein (rat homolog)-like 2). [sptrembl;acc:q96kw2]	3359	POM121L2		203.07	199.966	1.01552
b9 protein; likely ortholog of mouse endothelial precursor protein b9. [refseq;acc:nm_015681]	125	B9D1		213.243	227.616	1.0674
	181		High confidence	229.818	267.265	1.16294
ba127l20.1 (novel glutathione-s-transferase). [sptrembl;acc:q9h4y5]	41	GSTO2	Low confidence	228.147	200.55	1.13761
	244		High confidence	227.357	254.15	1.11785
ba138e2.1.2 (formin-binding protein 17 (fbp17), isoform 2). [sptrembl;acc:q96lh6]	464	FNBP1		210.578	226.764	1.07686
	983		Low confidence	201.215	196.378	1.02463
ba161i19.3 (similar to ribosomal protein l36). [sptrembl;acc:q8wx03]	608	no value		205.117	211.213	1.02972
ba203i16.1 (hypothetical protein kiaa0970). [sptrembl;acc:q9h1w1]	3117	FNDC3A	High confidence	0.00001	0.00001	1
	3814		Low confidence	205.397	202.717	1.01322
ba207c16.2 (fragment). [sptrembl;acc:q9nql7]	2599	KIAA1432	High confidence	211.662	211.361	1.00142
	3146		Low confidence	201.676	198.45	1.01626
ba271b5.1 (similar to ribosomal protein s7). [sptrembl;acc:q9h1s9]	1596	no value		205.496	201.273	1.02098
	2148		High confidence	217.871	219.366	1.00686
ba304i5.1 (novel lipase) (fragment). [sptrembl;acc:q96lg2]	2115	LIPM		214.632	213.14	1.007
	2524		Low confidence	196.878	193.373	1.01813
ba305p22.3 (breast carcinoma amplified sequence 4). [sptrembl;acc:q8ndy6]	931	BHLHB4	High confidence	159.13	164.917	1.03637
	4976		Low confidence	197.195	197.038	1.0008

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.