MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Value Type	Hugo	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 980 to 1029 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	Interaction Map	red	network_comparison	green
adenosylhomocysteinase (ec 3.3.1.1) (s-adenosyl-l-homocysteine hydrolase) (adohcyase). [swissprot;acc:p23526]	1576	AHCY	Subtracted	High confidence	215.389	3.556	211.833
	1910			Low confidence	201.465	3.894	197.571
	1929		Divided			1.01971
adenovirus 5 e1a-binding protein (bs69 protein). [swissprot;acc:q15326]	2491	ZMYND11	Subtracted	High confidence	217.417	0.573	216.844
	2502		Divided			1.00264
	3388		Subtracted	Low confidence	202.077	3.036	199.041
	3417		Divided			1.01525
adenylate cyclase, type v (ec 4.6.1.1) (atp pyrophosphate-lyase) (adenylyl cyclase) (fragment). [swissprot;acc:o95622]	376	ADCY5	Subtracted	High confidence	248.152	19.074	267.226
	467		Divided			1.07686
	3745			Low confidence	201.897	1.01348	199.211
	3755		Subtracted			2.686
adenylate cyclase, type vi (ec 4.6.1.1) (atp pyrophosphate-lyase) (ca(2+)-inhibitable adenylyl cyclase). [swissprot;acc:o43306]	375	ADCY6		High confidence	248.152	19.074	267.226
	466		Divided			1.07686
	3744			Low confidence	201.897	1.01348	199.211
	3754		Subtracted			2.686
adenylate kinase isoenzyme 2, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p54819]	291	AK2		High confidence	241.509	22.654	264.163
	379		Divided			1.0938
	3201		Subtracted	Low confidence	201.971	3.181	198.79
	3213		Divided			1.016
adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]	259	no value	Subtracted	High confidence	242.14	23.556	265.696
	348		Divided			1.09728
	4280		Subtracted	Low confidence	208.138	1.879	210.017
	4467		Divided			1.00903
adenylosuccinate lyase (ec 4.3.2.2) (adenylosuccinase) (asl) (asase). [swissprot;acc:p30566]	1608	ADSL			199.691	1.02088	195.607
	1621		Subtracted			4.084
	2067		Divided	High confidence	193.226	1.00828	191.639
	2091		Subtracted			1.587
adenylosuccinate synthase-like 1. [refseq;acc:nm_152328]	1192	ADSSL1	Divided	Low confidence	199.02	1.02309	194.529
	1219		Subtracted			4.491
	1661		Divided	High confidence	204.437	1.01432	201.551
	1698		Subtracted			2.886
adenylosuccinate synthetase (ec 6.3.4.4) (imp--aspartate ligase) (adss) (ampsase). [swissprot;acc:p30520]	1200	ADSS	Divided	Low confidence	198.973	1.02303	194.493
	1230		Subtracted			4.48
	1665		Divided	High confidence	204.433	1.01423	201.564
	1700		Subtracted			2.869
adenylyl cyclase-associated protein 1 (cap 1). [swissprot;acc:q01518]	1670	CAP1		Low confidence	201.46	4.057	197.403
	1701		Divided			1.02055
	1850			High confidence	215.931	1.01097	213.587
	1852		Subtracted			2.344
adenylyl cyclase-associated protein 2 (cap 2). [swissprot;acc:p40123]	1668	CAP2		Low confidence	201.425	4.058	197.367
	1699		Divided			1.02056
	1886		Subtracted	High confidence	215.853	2.214	213.639
	1895		Divided			1.01036
adhesion regulating molecule 1 precursor (110 kda cell membrane glycoprotein) (gp110). [swissprot;acc:q16186]	2356	ADRM1	Subtracted		218.555	0.879	219.434
	2369		Divided			1.00402
	2427		Subtracted	Low confidence	203.221	3.619	199.602
	2525		Divided			1.01813
adipocyte plasma membrane-associated protein (bscv protein). [swissprot;acc:q9hdc9]	801	C20orf3	Subtracted	High confidence	212.386	9.399	221.785
	813		Divided			1.04425
	3832		Subtracted	Low confidence	201.394	2.601	198.793

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.