MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 980 to 1029 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
60s ribosomal protein l12. [swissprot;acc:p30050]	682	no value	Rooted	Subtracted	49.9858	45.4433	4.5425
	1931		Squared	Divided	12442.9	13606.9	1.09355
	2185		Measured		3586.32	3414.42	1.05035
	2431			Subtracted			171.9
	2486		Squared		12442.9	13606.9	1164
60s ribosomal protein l13, mitochondrial (l13mt). [swissprot;acc:q9byd1]	325	MRPL13	Ranked		241.828	263.62	21.792
	390			Divided			1.09011
	533		Rooted		50.8036	46.8198	1.08509
	829			Subtracted			3.9838
	1783		Squared	Divided	13244.1	14564.4	1.09969
	2406			Subtracted			1320.3
	2447		Measured	Divided	3730.53	3611.05	1.03309
	2527			Subtracted			119.48
60s ribosomal protein l13a (23 kda highly basic protein). [swissprot;acc:p40429]	327	RPL13A	Ranked		241.83	263.615	21.785
	392			Divided			1.09008
	535		Rooted		50.8041	46.8218	1.08505
	831			Subtracted			3.9823
	1782		Squared	Divided	13245.8	14566.6	1.09971
	2404			Subtracted			1320.8
	2449		Measured	Divided	3730.74	3611.45	1.03303
	2529			Subtracted			119.29
60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]	222	no value	Ranked		242.153	266.673	24.52
	306			Divided			1.10126
	387		Rooted		50.3345	45.6718	1.10209
	658			Subtracted			4.6627
	2003		Squared	Divided	12429.9	13562.6	1.09113
	2074		Measured		3614.91	3423.89	1.05579
	2392			Subtracted			191.02
	2504		Squared		12429.9	13562.6	1132.7
60s ribosomal protein l15. [swissprot;acc:p39030]	577	RPL15	Ranked		217.862	230.978	13.116
	604			Divided			1.0602
	1089		Squared		17766.4	20351.7	1.14552
	1546			Subtracted			2585.3
	2238		Rooted	Divided	59.1718	57.9477	1.02112
	2312			Subtracted			1.2241
	2530		Measured		4888.72	5006.1	117.38
	2532			Divided			1.02401
60s ribosomal protein l17 (l23). [swissprot;acc:p18621]	200	no value	Ranked	Subtracted	241.808	267.335	25.527
	281			Divided			1.10557
	343		Rooted		50.3169	45.4333	1.10749
	590			Subtracted			4.8836
	1894		Measured	Divided	3598.08	3384.59	1.06308
	2212		Squared		12360.4	13390.2	1.08331
	2362		Measured	Subtracted	3598.08	3384.59	213.49
	2538		Squared		12360.4	13390.2	1029.8
60s ribosomal protein l18. [swissprot;acc:q07020]	411	RPL18	Ranked		237.109	254.667	17.558
	485			Divided			1.07405
	969		Rooted		52.9804	50.0947	1.0576
	1188			Subtracted			2.8857
	1618		Squared	Divided	15399.5	17067.9	1.10834

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.