MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Value Type	Hugo	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 958 to 1007 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	Interaction Map	red	network_comparison	green
adaptor-related protein complex 1, mu 1 subunit (mu-adaptin 1) (adaptor protein complex ap-1 mu-1 subunit) (golgi adaptor ha1/ap1 adaptin mu-1 subunit) (clathrin assembly protein assembly protein complex 1 medium chain 1) (clathrin coat assembly protein ap47) (clathrin coat associated protein ap47) (ap-mu chain family member mu1a). [swissprot;acc:q9bxs5]	553	AP1M1	Divided	Low confidence	205.75	1.03158	199.452
	1759		Subtracted	High confidence	221.082	2.696	223.778
	1770		Divided			1.01219
adaptor-related protein complex 1, mu 2 subunit (mu-adaptin 2) (adaptor protein complex ap-1 mu-2 subunit) (golgi adaptor ha1/ap1 adaptin mu-2 subunit) (clathrin assembly protein assembly protein complex 1 medium chain 2) (ap-mu chain family member mu1b). [swissprot;acc:q9y6q5]	541	AP1M2	Subtracted	Low confidence	205.768	6.315	199.453
	551		Divided			1.03166
	1723		Subtracted	High confidence	221.185	2.785	223.97
	1751		Divided			1.01259
adenine phosphoribosyltransferase (ec 2.4.2.7) (aprt). [swissprot;acc:p07741]	1027	no value	Subtracted		211.449	6.549	217.998
	1049		Divided			1.03097
	2462			Low confidence	199.981	1.0183	196.388
	2472		Subtracted			3.593
adenomatous polyposis coli like. [refseq;acc:nm_005883]	128	APC2			222.34	13.207	235.547
	161		Divided			1.0594
adenomatous polyposis coli protein (apc protein). [swissprot;acc:p25054]	127	APC	Subtracted		222.31	13.228	235.538
	160		Divided			1.0595
adenosine deaminase (ec 3.5.4.4) (adenosine aminohydrolase). [swissprot;acc:p00813]	1070	no value	Subtracted		202.317	4.716	197.601
	1075		Divided			1.02387
adenosine kinase (ec 2.7.1.20) (ak) (adenosine 5'-phosphotransferase). [swissprot;acc:p55263]	2151	ADK			200.658	1.0191	196.898
	2154		Subtracted			3.76
	2563		Divided	High confidence	208.429	1.00168	208.779
	2564		Subtracted			0.35
adenosylhomocysteinase (ec 3.3.1.1) (s-adenosyl-l-homocysteine hydrolase) (adohcyase). [swissprot;acc:p23526]	1553	AHCY	Divided		215.389	1.01679	211.833
	1576		Subtracted			3.556
	1910			Low confidence	201.465	3.894	197.571
	1929		Divided			1.01971
adenovirus 5 e1a-binding protein (bs69 protein). [swissprot;acc:q15326]	2491	ZMYND11	Subtracted	High confidence	217.417	0.573	216.844
	2502		Divided			1.00264
	3388		Subtracted	Low confidence	202.077	3.036	199.041
	3417		Divided			1.01525
adenylate cyclase, type v (ec 4.6.1.1) (atp pyrophosphate-lyase) (adenylyl cyclase) (fragment). [swissprot;acc:o95622]	376	ADCY5	Subtracted	High confidence	248.152	19.074	267.226
	467		Divided			1.07686
	3745			Low confidence	201.897	1.01348	199.211
	3755		Subtracted			2.686
adenylate cyclase, type vi (ec 4.6.1.1) (atp pyrophosphate-lyase) (ca(2+)-inhibitable adenylyl cyclase). [swissprot;acc:o43306]	375	ADCY6		High confidence	248.152	19.074	267.226
	466		Divided			1.07686
	3744			Low confidence	201.897	1.01348	199.211
	3754		Subtracted			2.686
adenylate kinase isoenzyme 2, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p54819]	291	AK2		High confidence	241.509	22.654	264.163
	379		Divided			1.0938
	3201		Subtracted	Low confidence	201.971	3.181	198.79
	3213		Divided			1.016
adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]	259	no value	Subtracted	High confidence	242.14	23.556	265.696
	348		Divided			1.09728
	4280		Subtracted	Low confidence	208.138	1.879	210.017
	4467		Divided			1.00903
adenylosuccinate lyase (ec 4.3.2.2) (adenylosuccinase) (asl) (asase). [swissprot;acc:p30566]	1608	ADSL			199.691	1.02088	195.607
	1621		Subtracted			4.084
	2067		Divided	High confidence	193.226	1.00828	191.639
	2091		Subtracted			1.587
adenylosuccinate synthase-like 1. [refseq;acc:nm_152328]	1192	ADSSL1	Divided	Low confidence	199.02	1.02309	194.529

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.