MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Network Comparison Type	Gene	Value Type	Hugo	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 912 to 961 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Network Comparison Type	Hugo	red	network_comparison	green
c-terminal binding protein 2 (ctbp2). [swissprot;acc:p56545]	1633	Subtracted	CTBP2	196.171	3.194	192.977
c-type lectin superfamily member 1 precursor (cartilage-derived c-type lectin). [swissprot;acc:o75596]	844	Divided	CLEC3A	178.033	1.04223	170.82
	953	Subtracted			7.213
c1 domain-containing phosphatase and tensin-like protein isoform 2; putative protein tyrosine phosphatase; c1 domain-containing phosphatase and tensin-like protein; tensin 2. [refseq;acc:nm_015319]	2465		TENC1	218.219	0.648	217.571
	2475	Divided			1.00298
c18b11 homolog (44.9kd). [refseq;acc:nm_152260]	1610	Subtracted	RPUSD2	217.446	3.246	214.2
	1625	Divided			1.01515
c316g12.2 (novel protein similar to predicted yeast, worm and archae- bacterial proteins) (similar to und313) (s. cervisiae) (hypothetical protein). [sptrembl;acc:q9ujk0]	1506		C16orf42	212.103	1.01807	208.339
	1520	Subtracted			3.764
c367g8.3 (novel protein similar to rpl23a (60s ribosomal protein l23a)) (60s ribosomal protein l23a like). [sptrembl;acc:q9br02]	242		no value	241.892	24.067	265.959
	321	Divided			1.09949
c439a6.1 (novel protein similar to heparan sulfate (glucosamine) 3-o- sulfotransferases) (fragment). [sptrembl;acc:q96qi5]	260		HS3ST6	219.421	1.11394	196.978
	293	Subtracted			22.443
ca2+-dependent endoplasmic reticulum nucleoside diphosphatase; apyrase; soluble calcium-activated nucleotidase scan-1. [refseq;acc:nm_138793]	2577	Divided	CANT1	192.625	1.00154	192.922
	2626	Subtracted			0.297
caax prenyl protease 1 homolog (ec 3.4.24.-) (prenyl protein-specific endoprotease 1) (farnesylated-proteins converting enzyme 1) (face-1) (zinc metalloproteinase ste24 homolog). [swissprot;acc:o75844]	1394		ZMPSTE24	226.532	4.415	222.117
	1448	Divided			1.01988
cab2. [refseq;acc:nm_033419]	750	Subtracted	PERLD1	210.946	10.279	221.225
	769	Divided			1.04873
cad protein [includes: glutamine-dependent carbamoyl-phosphate synthase (ec 6.3.5.5); aspartate carbamoyltransferase (ec 2.1.3.2); dihydroorotase (ec 3.5.2.3)]. [swissprot;acc:p27708]	1818	Subtracted	CAD	212.884	2.439	215.323
	1829	Divided			1.01146
cadherin-related tumor suppressor homolog precursor (fat protein homolog). [swissprot;acc:q14517]	1506	Subtracted	FAT	219.306	3.873	223.179
	1526	Divided			1.01766
calcipressin 1 (down syndrome critical region protein 1) (myocyte- enriched calcineurin interacting protein 1) (mcip1) (adapt78). [swissprot;acc:p53805]	1306	Subtracted	RCAN1	218.508	4.86	213.648
	1330	Divided			1.02275
calcipressin 2 (thyroid hormone-responsive protein zaki-4) (down syndrome candidate region 1-like 1) (myocyte-enriched calcineurin interacting protein 2) (mcip2). [swissprot;acc:q14206]	1305	Subtracted	RCAN2	218.509	4.86	213.649
	1328	Divided			1.02275
calcipressin 3 (down syndrome candidate region 1-like protein 2) (myocyte-enriched calcineurin interacting protein 3) (mcip3). [swissprot;acc:q9uka8]	1307	Subtracted	RCAN3		4.86
	1331	Divided			1.02275
calcium-binding mitochondrial carrier protein aralar1 (solute carrier family 25, member 12). [swissprot;acc:o75746]	2494		SLC25A12	194.527	1.00284	195.08
	2505	Subtracted			0.553
calcium-binding mitochondrial carrier protein aralar2 (solute carrier family 25, member 13) (citrin). [swissprot;acc:q9ujs0]	2497	Divided	SLC25A13		1.00284
	2508	Subtracted			0.553
calcium-dependent protease, small subunit (calpain regulatory subunit) (calcium-activated neutral proteinase) (canp). [swissprot;acc:p04632]	940	Divided	CAPNS1	212.442	1.03586	205.088
		Subtracted			7.354
calcium-transporting atpase type 2c, member 1 (ec 3.6.3.8) (atpase 2c1) (atp-dependent ca(2+) pump pmr1) (hussy-28). [swissprot;acc:p98194]	1082		ATP2C1	209.052	5.869	203.183
	1100	Divided			1.02889
calcium/calmodulin-dependent protein kinase type ii alpha chain (ec 2.7.1.123) (cam-kinase ii alpha chain) (cam kinase ii alpha subunit) (camk-ii alpha subunit). [swissprot;acc:q9uqm7]	2148	Subtracted	CAMK2A	215.925	1.444	214.481
	2172	Divided			1.00673
calcium/calmodulin-dependent protein kinase type ii beta chain (ec 2.7.1.123) (cam-kinase ii beta chain) (cam kinase ii beta subunit) (camk-ii beta subunit). [swissprot;acc:q13554]	2149	Subtracted	CAMK2B		1.444
	2173	Divided			1.00673
calcium/calmodulin-dependent protein kinase type ii delta chain (ec 2.7.1.123) (cam-kinase ii delta chain) (cam kinase ii delta subunit) (camk-ii delta subunit). [swissprot;acc:q13557]	2139	Subtracted	CAMK2D		1.444
	2162	Divided			1.00673
calcium/calmodulin-dependent protein kinase type ii gamma chain (ec 2.7.1.123) (cam-kinase ii gamma chain) (cam kinase ii gamma subunit) (camk-ii gamma subunit) (fragment). [swissprot;acc:q13555]	2138	Subtracted	CAMK2G		1.444
	2161	Divided			1.00673
calcyphosine. [swissprot;acc:q13938]	563		CAPS	220.744	1.06577	207.121
	565	Subtracted			13.623
calmegin precursor. [swissprot;acc:o14967]	1880		CLGN	217.48	2.224	215.256
	1909	Divided			1.01033
calmodulin. [swissprot;acc:p02593]	2928		no value	0.00001	1	0.00001

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.