MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Rank	Gene	Value Type	Hugo	Network Comparison Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 8914 to 8963 of 16578 in total

Value Type  : Ranked
Filtered  : 1

description	Rank	Hugo	Network Comparison Type	Interaction Map	red	network_comparison	green
n27c7-4 protein. [sptrembl;acc:q8wyq3]	3337	C22orf16	Subtracted	Low confidence	198.986	3.088	195.898
n33 protein. [swissprot;acc:q13454]	22	TUSC3	Divided		198	1.21472	163
	26		Subtracted			35
nad synthetase 1; glutamine-dependent nad synthetase. [refseq;acc:nm_018161]	3394	NADSYN1	Divided		200.316	1.01531	197.295
	3402		Subtracted			3.021
nad(p) dependent steroid dehydrogenase-like. [refseq;acc:nm_145168]	1957	no value			202.786	3.867	198.919
	2007		Divided			1.01944
nad(p)-dependent steroid dehydrogenase (ec 1.1.1.-) (h105e3 protein). [swissprot;acc:q15738]	1743	NSDHL			199.249	1.02038	195.27
	1763		Subtracted			3.979
nad-dependent malic enzyme, mitochondrial precursor (ec 1.1.1.38) (nad-me) (malic enzyme 2). [swissprot;acc:p23368]	2554	ME2	Divided		197.462	1.01806	193.959
	2634		Subtracted			3.503
nadh-cytochrome b5 reductase (ec 1.6.2.2) (b5r). [swissprot;acc:p00387]	1337	CYB5R3	Divided		200.614	1.02214	196.269
	1364		Subtracted			4.345
	1863		Divided	High confidence	210.856	1.01087	213.147
	1867		Subtracted			2.291
nadh-ubiquinone oxidoreductase 13 kda-a subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-a) (ci-13kd-a). [swissprot;acc:o75380]	1705	NDUFS6			233.45	2.855	230.595
	1762		Divided			1.01238
	2714		Subtracted	Low confidence	201.614	3.457	198.157
	2757		Divided			1.01745
nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718]	851	NDUFA5	Subtracted		203.141	5.073	198.068
	872		Divided			1.02561
	3005			High confidence	0.00001	1	0.00001
			Subtracted		0	0	0
nadh-ubiquinone oxidoreductase 18 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-18 kda) (ci-18 kda) (complex i- aqdq) (ci-aqdq). [swissprot;acc:o43181]	53	NDUFS4			318.982	59.978	259.004
	119		Divided			1.23157
	126		Subtracted	Low confidence	226.892	13.231	213.661
	146		Divided			1.06193
nadh-ubiquinone oxidoreductase 23 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-23kd) (ci-23kd) (tyky subunit). [swissprot;acc:o00217]	854	NDUFS8	Subtracted	High confidence	227.596	8.579	219.017
	885		Divided			1.03917
	3193		Subtracted	Low confidence	200.654	3.187	203.841
	3242		Divided			1.01588
nadh-ubiquinone oxidoreductase 24 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3). [swissprot;acc:p19404]	2795	NDUFV2		High confidence	0.00001	1	0.00001
			Subtracted		0	0	0
	3888			Low confidence	203.49	2.531	200.959
	3906		Divided			1.01259
nadh-ubiquinone oxidoreductase 30 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-30kd) (ci-30kd). [swissprot;acc:o75489]	852	PTPMT1	Subtracted		203.141	5.073	198.068
	873		Divided			1.02561
	3081			High confidence	0.00001	1	0.00001
			Subtracted		0	0	0
nadh-ubiquinone oxidoreductase 39 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-39kd) (ci-39kd). [swissprot;acc:q16795]	309	NDUFA9		Low confidence	205.75	8.266	197.484
	310		Divided			1.04186
	2954			High confidence	0.00001	1	0.00001
			Subtracted		0	0	0
nadh-ubiquinone oxidoreductase 42 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-42kd) (ci-42kd). [swissprot;acc:o95299]	4906	NDUFA10		Low confidence	203.146	0.382	202.764
	4909		Divided			1.00188
nadh-ubiquinone oxidoreductase 49 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-49kd) (ci-49kd). [swissprot;acc:o75306]	2438	NDUFS2	Subtracted		202.66	3.613	199.047
	2514		Divided			1.01815
	2878			High confidence	0.00001	1	0.00001
			Subtracted		0	0	0
nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-75kd) (ci-75kd). [swissprot;acc:p28331]	4027	NDUFS1		Low confidence	204.634	2.297	202.337

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.