MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 891 to 940 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	Network Comparison Type	red	green	network_comparison
60 kda heat shock protein, mitochondrial precursor (hsp60) (60 kda chaperonin) (cpn60) (heat shock protein 60) (hsp-60) (mitochondrial matrix protein p1) (p60 lymphocyte protein) (hucha60). [swissprot;acc:p10809]	1313	HSPD1	Measured	Divided	5457.14	5899.85	1.08112
	1461			Subtracted			442.71
	1830		Rooted	Divided	60.2038	62.0316	1.03036
	1918			Subtracted			1.8278
	2574		Ranked		222.305	222.64	0.335
	2588			Divided			1.00151
60 kda tat interactive protein (tip60) (hiv-1 tat interactive protein) (cpla(2) interacting protein). [swissprot;acc:q92993]	808	HTATIP		Subtracted	223.186	213.912	9.274
	821		Rooted	Divided	61.3164	65.2371	1.06394
	826		Ranked		223.186	213.912	1.04335
	849		Rooted	Subtracted	61.3164	65.2371	3.9207
	1682		Measured		6011.57	6414.98	403.41
	1751			Divided			1.06711
	2558		Squared	Subtracted	31749.4	30796.3	953.1
	2621			Divided			1.03095
60s acidic ribosomal protein p0 (l10e). [swissprot;acc:p05388]	1022	RPLP0	Ranked	Subtracted	226.203	232.855	6.652
	1092			Divided			1.02941
	2112		Squared	Subtracted	22719.3	24581.5	1862.2
	2254			Divided			1.08197
	2258		Measured		5150.31	5388.05	1.04616
	2317			Subtracted			237.74
	2720		Rooted	Divided	58.3416	58.4068	1.00112
	2730			Subtracted			0.0652
60s acidic ribosomal protein p1. [swissprot;acc:p05386]	831	no value	Ranked		229.171	238.048	8.877
	898			Divided			1.03874
	2296		Squared	Subtracted	20706.1	22261.9	1555.8
	2326			Divided			1.07514
	2409		Measured	Subtracted	4857.03	5039.78	182.75
	2418			Divided			1.03763
	2564		Rooted		56.832	56.3214	1.00907
	2591			Subtracted			0.5106
60s acidic ribosomal protein p2. [swissprot;acc:p05387]	621	RPLP2	Ranked		231.92	244.435	12.515
	720			Divided			1.05396
	1708		Rooted		56.1247	54.3497	1.03266
	1974			Subtracted			1.775
	2743		Measured	Divided	4824.49	4813.92	1.0022
	2744			Subtracted			10.57
	2745		Squared	Divided	21770.6	21696.3	1.00342
	2746			Subtracted			74.3
60s ribosomal protein l10 (qm protein) (tumor suppressor qm) (laminin receptor homolog). [swissprot;acc:p27635]	267	no value	Ranked		243.12	266.661	23.541
	357			Divided			1.09683
	444		Rooted		50.1636	45.7275	1.09701
	716			Subtracted			4.4361
	1895		Squared	Divided	12581.2	13765.5	1.09413
	2233		Measured		3614.08	3450.07	1.04754
	2452			Subtracted			164.01
	2472		Squared		12581.2	13765.5	1184.3
60s ribosomal protein l10a (csa-19). [swissprot;acc:p53025]	264		Ranked		243.24	266.796	23.556
	356			Divided			1.09684
	443		Rooted		50.1766	45.7369	1.09707
	715			Subtracted			4.4397

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.