MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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Rank	Gene	Hugo	description	Network Comparison Type	Value Type	Interaction Map	red	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 880 to 929 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
red  : 0
Filtered  : 1
green  : 0
network_comparison  : 0

Rank	Hugo	description	Value Type
2975	KCTD3	potassium channel tetramerisation domain containing 3; ny-ren-45 antigen. [refseq;acc:nm_016121]	Rooted
2976	CAB39	mo25 protein (cgi-66). [swissprot;acc:q9y376]	Measured
			Ranked
			Squared
			Rooted
2977	CYP27A1	cytochrome p450 27, mitochondrial precursor (ec 1.14.-.-) (cytochrome p-450c27/25) (sterol 26-hydroxylase) (sterol 27-hydroxylase) (vitamin d(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase). [swissprot;acc:q02318]	Measured
			Ranked
			Squared
			Rooted
2978	ITGA7	integrin alpha-7 precursor. [swissprot;acc:q13683]	Measured
			Ranked
			Squared
			Rooted
2979	UGT2B28	udp-glucuronosyltransferase 2b28 precursor, microsomal (ec 2.4.1.17). [swissprot;acc:q9by64]	Measured
			Ranked
			Squared
			Rooted
2980	TAOK3	ste20-like kinase; ste2-like kinase. [refseq;acc:nm_016281]	Measured
			Ranked
			Squared
			Rooted
2981	DZIP1	zinc finger daz interacting protein 1. [refseq;acc:nm_014934]	Measured
			Ranked
			Squared
			Rooted
2982	no value	serine/threonine protein kinase mask; ste20-like kinase mst4. [refseq;acc:nm_016542]	Measured
			Ranked
			Squared
			Rooted
2983	CCNH	cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946]	Measured
			Ranked
			Squared
			Rooted
2984	MED10	similar to cg5057 gene product. [sptrembl;acc:q9btt4]	Measured
			Ranked
			Squared
			Rooted
2985	MYH11	myosin heavy chain, smooth muscle isoform (smmhc). [swissprot;acc:p35749]	Measured
			Ranked
			Squared
			Rooted
2986	CSNK1G2	casein kinase i, gamma 2 isoform (ec 2.7.1.-) (cki-gamma 2). [swissprot;acc:p78368]	Measured
			Ranked
			Squared
			Rooted
2987	SPG20	spartin; trans-activated by hepatitis c virus core protein 1. [refseq;acc:nm_015087]	Measured
			Ranked
			Squared
			Rooted
2988	MYH10	myosin heavy chain, nonmuscle type b (cellular myosin heavy chain, type b) (nonmuscle myosin heavy chain-b) (nmmhc-b). [swissprot;acc:p35580]	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.