MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Network Comparison Type	Gene	Value Type	Rank	Hugo	Interaction Map	red	Filtered	network_comparison	green

Results: HTML CSV LaTeX

Showing element 862 to 911 of 2060 in total

Network Comparison Type  : Subtracted
red  : 0
Filtered  : 1
network_comparison  : 0
green  : 0

description	Value Type	Rank	Hugo	Interaction Map
lyl-1 protein (lymphoblastic leukemia derived sequence 1). [swissprot;acc:p12980]	Ranked	3107	LYL1	High confidence
	Squared
	Rooted
lysosomal trafficking regulator (beige homolog). [swissprot;acc:q99698]	Measured	2929	LYST
	Ranked
	Squared
	Rooted
mab-21-like protein 1; mab-21-like 1. [refseq;acc:nm_005584]	Measured	2786	MAB21L1
	Ranked
	Squared
	Rooted
mab-21-like protein 2; mab-21-like 2. [refseq;acc:nm_006439]	Measured	2783	MAB21L2
	Ranked
	Squared
	Rooted
mago nashi protein homolog. [swissprot;acc:p50606]	Measured	2864	MAGOH
	Ranked
	Squared
	Rooted
major centromere autoantigen b (centromere protein b) (cenp-b). [swissprot;acc:p07199]	Measured	3013	CENPB
		5040		Low confidence
	Ranked	3013		High confidence
		5039		Low confidence
	Squared	3013		High confidence
		5040		Low confidence
	Rooted	3013		High confidence
		5040		Low confidence
malate dehydrogenase, cytoplasmic (ec 1.1.1.37). [swissprot;acc:p40925]	Measured	3213	MDH1	High confidence
	Ranked
	Squared
	Rooted
mam domain containing glycosylphosphatidylinositol anchor 1; glycosyl-phosphatidyl-inositol-mam. [refseq;acc:nm_153487]	Measured	3070	MDGA1
	Ranked
	Squared
	Rooted
membrane-bound transcription factor site 2 protease (ec 3.4.24.-) (site-2 protease) (sterol-regulatory element-binding proteins intramembrane protease). [swissprot;acc:o43462]	Measured	3215	MBTPS2
	Ranked
	Squared
	Rooted
microfibrillar-associated protein 1. [swissprot;acc:p55081]	Measured	2949	MFAP1
	Ranked
	Squared
	Rooted
microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]	Measured	2880	no value
	Ranked
	Squared
	Rooted
mitochondrial 28s ribosomal protein s30 (s30mt) (mrp-s30) (programmed cell death protein 9) (bm047). [swissprot;acc:q9np92]	Measured	3063	MRPS30
	Ranked
	Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.