MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	red	Network Comparison Type	Gene	Rank	Hugo	network_comparison	Value Type	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 808 to 857 of 2060 in total

red  : 0
Network Comparison Type  : Subtracted
network_comparison  : 0
Filtered  : 1
green  : 0

description	Rank	Hugo	Value Type	Interaction Map
lactamase, beta 2. [refseq;acc:nm_016027]	2914	LACTB2	Rooted	High confidence
langerhans cell specific c-type lectin. [refseq;acc:nm_015717]	3046	CD207	Measured
			Ranked
			Squared
			Rooted
	5044		Ranked	Low confidence
	5045		Measured
			Squared
			Rooted
late endosomal/lysosomal mp1 interacting protein (p14) (hspc003). [swissprot;acc:q9y2q5]	3044	no value	Measured	High confidence
			Ranked
			Squared
			Rooted
	5043		Ranked	Low confidence
	5044		Measured
			Squared
			Rooted
leucine rich repeat (in flii) interacting protein 1. [refseq;acc:nm_004735]	3017	LRRFIP1	Measured	High confidence
			Ranked
			Squared
			Rooted
	5040		Ranked	Low confidence
	5041		Measured
			Squared
			Rooted
leucine rich repeat (in flii) interacting protein 2. [refseq;acc:nm_006309]	3153	LRRFIP2	Measured	High confidence
			Ranked
			Squared
			Rooted
	5057		Measured	Low confidence
			Ranked
			Squared
			Rooted
likely ortholog of mouse c-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 13; c-type lectin 13; likely ortholog of rat kupffer cell c-type lectin receptor. [refseq;acc:nm_173535]	2898	CLEC4F	Measured	High confidence
			Ranked
			Squared
			Rooted
	5028		Ranked	Low confidence
	5029		Measured
			Squared
			Rooted
lipin 1. [swissprot;acc:q14693]	5035	LPIN1	Ranked
	5036		Measured
			Squared
			Rooted
lipin 2. [swissprot;acc:q92539]	5050	LPIN2	Measured
			Ranked
			Squared
			Rooted
lipin 3 (lipin 3-like) (fragments). [swissprot;acc:q9bqk8]	5036	LPIN3	Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.