MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Proteome Analysis

Below the proteome analysis is presented. The analysis methods are presented in the paper Propagating Differential Gene Expression in Protein Interaction Networks. If you are interested in the most reliable results choose the

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description	Gene	Rank	Hugo	Network Comparison Type	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 751 to 800 of 12912 in total

Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

description	Rank	Hugo	Value Type	red	green	network_comparison
acyl-coenzyme a oxidase 1, peroxisomal (ec 1.3.3.6) (palmitoyl-coa oxidase) (aox). [swissprot;acc:q15067]	2355	ACOX1	Rooted	70.7786	72.0362	1.01777
	2643		Ranked	194.097	194.328	1.00119
acyl-coenzyme a oxidase 2, peroxisomal (ec 1.3.3.6) (branched-chain acyl-coa oxidase) (brcacox) (trihydroxycoprostanoyl-coa oxidase) (thccox) (thca-coa oxidase). [swissprot;acc:q99424]	905	ACOX2	Squared	27382	31722.9	1.15853
	2154		Measured	6884.69	7247.36	1.05268
	2404		Ranked	193.389	194.105	1.0037
	2424		Rooted	70.8372	71.869	1.01457
ad24 protein. [refseq;acc:nm_022451]	348	NOC3L		49.2558	54.5235	1.10695
	445		Measured	3753.71	4315.95	1.14978
	505		Ranked	251.334	234.672	1.071
	1305		Squared	14354.8	16210.8	1.12929
adamts-9 precursor (ec 3.4.24.-) (a disintegrin and metalloproteinase with thrombospondin motifs 9) (adam-ts 9) (adam-ts9). [swissprot;acc:q9p2n4]	1530	ADAMTS9	Measured	5916.05	6350.53	1.07344
	1685		Squared	27060.6	29916.8	1.10555
	1855		Rooted	62.7784	64.64	1.02965
	2516		Ranked	215.835	216.341	1.00234
adapter-related protein complex 1 beta 1 subunit (beta-adaptin 1) (adaptor protein complex ap-1 beta-1 subunit) (golgi adaptor ha1/ap1 adaptin beta subunit) (clathrin assembly protein complex 1 beta large chain). [swissprot;acc:q10567]	1586	AP1B1		222.166	225.79	1.01631
	2064		Measured	5548.79	5861.31	1.05632
	2079		Squared	25451.6	27731.3	1.08957
	2443		Rooted	60.3943	61.2421	1.01404
adapter-related protein complex 1 gamma 1 subunit (gamma-adaptin) (adaptor protein complex ap-1 gamma-1 subunit) (golgi adaptor ha1/ap1 adaptin gamma-1 subunit) (clathrin assembly protein complex 1 gamma-1 large chain). [swissprot;acc:o43747]	1596	AP1G1	Ranked	222.134	225.731	1.01619
	2059		Measured	5552.69	5865.84	1.0564
	2081		Squared	25481.8	27764	1.08956
	2439		Rooted	60.4127	61.2677	1.01415
adapter-related protein complex 1 gamma 2 subunit (gamma2-adaptin) (adaptor protein complex ap-1 gamma-2 subunit) (g2ad). [swissprot;acc:o75843]	1594	JPH4	Ranked	222.133	225.731	1.0162
	2062		Measured	5552.7	5865.85	1.0564
	2080		Squared	25481.8	27764.1	1.08957
	2442		Rooted	60.4127	61.2677	1.01415
adapter-related protein complex 1 sigma 1a subunit (sigma-adaptin 1a) (adaptor protein complex ap-1 sigma-1a subunit) (golgi adaptor ha1/ap1 adaptin sigma-1a subunit) (clathrin assembly protein complex 1 sigma- 1a small chain) (clathrin coat assembly protein ap19) (ha1 19 kda subunit) (sigma 1a subunit of ap-1 clathrin). [swissprot;acc:q00382]	1598	AP1S1	Ranked	222.134	225.731	1.01619
	2061		Measured	5552.69	5865.84	1.0564
	2078		Squared	25481.8	27764.1	1.08957
	2441		Rooted	60.4127	61.2677	1.01415
adapter-related protein complex 1 sigma 1b subunit (sigma-adaptin 1b) (adaptor protein complex ap-1 sigma-1b subunit) (golgi adaptor ha1/ap1 adaptin sigma-1b subunit) (clathrin assembly protein complex 1 sigma- 1b small chain) (sigma 1b subunit of ap-1 clathrin) (dc22). [swissprot;acc:p56377]	1595	no value	Ranked	222.134	225.731	1.01619
	2058		Measured	5552.69	5865.84	1.0564
	2076		Squared	25481.8	27764.1	1.08957
	2438		Rooted	60.4127	61.2677	1.01415
adapter-related protein complex 1 sigma 1c subunit (sigma-adaptin 1c) (adaptor protein complex ap-1 sigma-1c subunit) (golgi adaptor ha1/ap1 adaptin sigma-1c subunit) (clathrin assembly protein complex 1 sigma- 1c small chain) (sigma 1c subunit of ap-1 clathrin). [swissprot;acc:q96pc3]	1597	AP1S3	Ranked	222.134	225.731	1.01619
	2060		Measured	5552.69	5865.84	1.0564
	2077		Squared	25481.8	27764.1	1.08957
	2440		Rooted	60.4127	61.2677	1.01415
adapter-related protein complex 2 beta 1 subunit (beta-adaptin) (plasma membrane adaptor ha2/ap2 adaptin beta subunit) (clathrin assembly protein complex 2 beta large chain) (ap105b). [swissprot;acc:p21851]	1600	AP2B1	Ranked	222.103	225.675	1.01608
	2050		Measured	5556.36	5870.11	1.05647
	2082		Squared	25510.2	27794.9	1.08956
	2429		Rooted	60.43	61.2917	1.01426
adapter-related protein complex 3 beta 1 subunit (beta-adaptin 3a) (ap-3 complex beta-3a subunit) (beta-3a-adaptin). [swissprot;acc:o00203]	2044	AP3B1	Ranked	199.928	198.24	1.00851
	2376		Rooted	68.9441	70.0808	1.01649
	2623		Measured	6815.24	6916.14	1.01481
	2726		Squared	30233.2	29898.1	1.01121
adapter-related protein complex 3 beta 2 subunit (beta-adaptin 3b) (ap-3 complex beta-3b subunit) (beta-3b-adaptin) (neuron-specific vesicle coat protein beta-nap). [swissprot;acc:q13367]	2046	no value	Ranked	199.928	198.24	1.00851
	2378		Rooted	68.9441	70.0808	1.01649
	2625		Measured	6815.24	6916.14	1.01481
	2728		Squared	30233.2	29898.1	1.01121

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.